PA14658

GABRA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14658-Each-of-1 In Stock ₹ 49,496.46

PA14658 - Each of 1

₹ 49,496.46

In Stock

Quantity

1

Base Price: ₹ 49,496.46

GST (18%): ₹ 8,909.363

Total Price: ₹ 58,405.823

Antigen

GABRA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GABRA1

Gene Alias

ECA4, EIEE19, EJM, EJM5, GABA alpha subunit, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABAA alpha 1, GABAAR alpha1, GABRA 1, GABRA1, Gabra-1, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1, gamma-aminobutyric acid A receptor alpha 1 variant 1, gamma-aminobutyric acid A receptor alpha 1 variant 2, gamma-aminobutyric acid A receptor alpha 1 variant 3, gamma-aminobutyric acid A receptor alpha 1 variant 4, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, gamma-aminobutyric acid receptor subunit alpha-1-like, gamma-aminobutyric acid type A receptor alpha1 subunit, gamma-aminobutyric acid type A receptor subunit alpha1, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14394, 29705

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

∽0.15 mg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P62812, P62813

Gene Symbols

GABRA1

Immunogen

Fusion protein from the cytoplasmic loop of the alpha 1 subunit of rat GABRA1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine, canine, human and non-human primate based on 100% sequence homology
  • This antibody is specific for the ∽51 kDa alpha1-subunit of the GABAA Receptor in Western blots of rat brain
  • Gamma -aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA Receptor (GABAA-R) subtype
  • GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse
  • The GABAA-R is a multimeric subunit complex
  • To date aix alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified
  • Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-R sensitive to GABA
  • However, coexpression of a gamma-subunit is required for benzodiazepine modulation
  • The various effects of the benzodiazepines in brain may also be mediated via different alpha-subunits of the receptor
  • Lastly, phosphorylation of beta-subunits of the receptor has been shown to modulate GABAA-R function.

Compare Similar Items

Show Difference

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Thermo Scientific

PA14658

--


Antigen:
GABRA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GABRA1

Gene Alias:
ECA4, EIEE19, EJM, EJM5, GABA alpha subunit, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABAA alpha 1, GABAAR alpha1, GABRA 1, GABRA1, Gabra-1, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1, gamma-aminobutyric acid A receptor alpha 1 variant 1, gamma-aminobutyric acid A receptor alpha 1 variant 2, gamma-aminobutyric acid A receptor alpha 1 variant 3, gamma-aminobutyric acid A receptor alpha 1 variant 4, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, gamma-aminobutyric acid receptor subunit alpha-1-like, gamma-aminobutyric acid type A receptor alpha1 subunit, gamma-aminobutyric acid type A receptor subunit alpha1, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14394, 29705

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
∽0.15 mg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P62812, P62813

Gene Symbols:
GABRA1

Immunogen:
Fusion protein from the cytoplasmic loop of the alpha 1 subunit of rat GABRA1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA14659

--


Antigen:
GluR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gria2

Gene Alias:
AMPA selective glutamate receptor; AMPA-selective glutamate receptor 2; GluA2; Glur2; GluR-2; GLURB; GluR-B; GluR-K2; glutamate ionotropic receptor AMPA type subunit 2; glutamate receptor; glutamate receptor 2; glutamate receptor B; glutamate receptor B flip isoform; glutamate receptor ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA2 (alpha 2); GRIA2; HBGR2; OTTHUMP00000165324; OTTHUMP00000220942; OTTHUMP00000220943

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29627

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P19491

Gene Symbols:
Gria2

Immunogen:
Synthetic peptide corresponding to amino acid residues specific to rat GluR2 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA14661

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Antigen:
GLRA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLRA1

Gene Alias:
GLRA; Glra1; Glra2; glycine receptor; Glycine receptor 48 kDa subunit; glycine receptor alpha 1; glycine receptor strychnine-binding subunit; Glycine receptor subunit alpha-1; glycine receptor, alpha 1; glycine receptor, alpha 1 subunit; Glyr; GLYRA1; gra1; HKPX1; nmf11; oscillator; ot; spasmodic; spd; STHE

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14654, 25674, 2741

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry, Western Blot

Concentration:
__

Formulation:
5mM Ammonium bicarbonate with no preservative; pH 7.4

Gene Accession No.:
P07727, P23415, Q64018

Gene Symbols:
GLRA1

Immunogen:
Synthetic peptide corresponding to the N-terminal region of rat GLRA1 conjugated to KLH

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA14662

--


Antigen:
GRASP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRIPAP1

Gene Alias:
30kDa C-terminus form; AI854681; DXImx47e; Grasp1; GRASP-1; GRASP-1 C-terminal chain; GRIP1; GRIP-1; GRIP1 associated protein 1; GRIP1-associated protein 1; Gripap1; GRIP-associated protein 1; HCMV-interacting protein; Kiaa1167; mKIAA1167; MPMGp800B12492Q3; Sfc10

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116493, 54645

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q8VD04, Q9JHZ4

Gene Symbols:
GRIPAP1

Immunogen:
Synthetic peptide corresponding to the C-terminal region of rat GRIPAP1 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG