PA14661

GLRA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14661-Each-of-1 In Stock ₹ 47,186.34

PA14661 - Each of 1

₹ 47,186.34

In Stock

Quantity

1

Base Price: ₹ 47,186.34

GST (18%): ₹ 8,493.541

Total Price: ₹ 55,679.881

Antigen

GLRA1

Classification

Polyclonal

Formulation

5mM Ammonium bicarbonate with no preservative; pH 7.4

Gene Accession No.

P07727, P23415, Q64018

Gene Symbols

GLRA1

Immunogen

Synthetic peptide corresponding to the N-terminal region of rat GLRA1 conjugated to KLH

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Gene

GLRA1

Gene Alias

GLRA; Glra1; Glra2; glycine receptor; Glycine receptor 48 kDa subunit; glycine receptor alpha 1; glycine receptor strychnine-binding subunit; Glycine receptor subunit alpha-1; glycine receptor, alpha 1; glycine receptor, alpha 1 subunit; Glyr; GLYRA1; gra1; HKPX1; nmf11; oscillator; ot; spasmodic; spd; STHE

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14654, 25674, 2741

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

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Description

  • This antibody is specific for the ∽48 kDa alpha 1 and alpha 2 subunits of the Glycine Receptor in Western blots of rat spinal cord and brain stem and in cell extracts, and does not recognize other Glycine Receptor subunits
  • Immunolabeling is blocked by preadsorption of antibody with the peptide immunogen
  • Reconstitute with 100 μL PBS
  • GLRA1 is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system
  • Defects in GLRA1 are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome
  • Multiple transcript variants encoding different isoforms have been found for GLRA1
  • Glycine receptors (GlyR) that include GLRA1 are members of the cys-loop family of ligand-gated ion channels, responsible for mediating the inhibitory effects of glycine
  • GLRA1 are widely distributed throughout the CNS, particularly within the hippocampus, spinal cord and brain stem
  • Diseases associated with GLRA1 include Hyperekplexia, Hereditary 1 and Hyperekplexia.

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Img

Thermo Scientific

PA14661

--


Antigen:
GLRA1

Classification:
Polyclonal

Formulation:
5mM Ammonium bicarbonate with no preservative; pH 7.4

Gene Accession No.:
P07727, P23415, Q64018

Gene Symbols:
GLRA1

Immunogen:
Synthetic peptide corresponding to the N-terminal region of rat GLRA1 conjugated to KLH

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
GLRA1

Gene Alias:
GLRA; Glra1; Glra2; glycine receptor; Glycine receptor 48 kDa subunit; glycine receptor alpha 1; glycine receptor strychnine-binding subunit; Glycine receptor subunit alpha-1; glycine receptor, alpha 1; glycine receptor, alpha 1 subunit; Glyr; GLYRA1; gra1; HKPX1; nmf11; oscillator; ot; spasmodic; spd; STHE

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14654, 25674, 2741

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Img

Thermo Scientific

PA14662

--


Antigen:
GRASP1

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q8VD04, Q9JHZ4

Gene Symbols:
GRIPAP1

Immunogen:
Synthetic peptide corresponding to the C-terminal region of rat GRIPAP1 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
GRIPAP1

Gene Alias:
30kDa C-terminus form; AI854681; DXImx47e; Grasp1; GRASP-1; GRASP-1 C-terminal chain; GRIP1; GRIP-1; GRIP1 associated protein 1; GRIP1-associated protein 1; Gripap1; GRIP-associated protein 1; HCMV-interacting protein; Kiaa1167; mKIAA1167; MPMGp800B12492Q3; Sfc10

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116493, 54645

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA14663

--


Antigen:
mGluR1/mGluR5

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P23385, P31424, P97772, Q3UVX5

Gene Symbols:
Grm1, Grm5

Immunogen:
Synthetic peptide corresponding to the C-terminal region of rat GRM5 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
Grm5

Gene Alias:
4930455H15Rik; 6430542K11Rik; AI850523; ENSMUSG00000075319; G protein coupled receptor family C group 1 member A; G protein coupled receptor, family C, group 1, member A; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member A; G protein-coupled receptor, family C, group 1, member E; Glu5R; glutamate metabotropic receptor 1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 1; glutamate receptor, metabotropic 5; Gm10828; GPRC1A; Gprc1e; Grm1; GRM5; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 1; Metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGLU1; mGlu5; mGluR1; mGluR5; mGluR5b; mGlurR1a; nmf373; PPP1R85; PPP1R86; protein phosphatase 1, regulatory subunit 85; protein phosphatase 1, regulatory subunit 86; rcw; SCAR13; wobl

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108071, 14816, 24414, 24418

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA14667

--


Antigen:
PSD-95

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P31016, Q62108

Gene Symbols:
DLG4

Immunogen:
Synthetic peptide corresponding to the N-terminal region of rat DLG4 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
DLG4

Gene Alias:
discs large homolog 4; discs large MAGUK scaffold protein 4; discs, large homolog 4; discs, large homolog 4 (Drosophila); disks large homolog 4; Dlg4; Dlgh4; FLJ97752; FLJ98574; post synaptic density; postsynaptic density protein 95; post-synaptic density protein 95; PSD95; PSD-95; PSD-95 alpha 2b; PSD-95 beta; Sap90; SAP-90; SAP90A; Synapse-associated protein 90; synapse-associated protein SAP90; Tax interaction protein 15

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13385, 29495

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid