PA1512
Glucocorticoid Receptor Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1512-Each-of-1 | In Stock | ₹ 48,726.42 |
PA1512 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,726.42
GST (18%): ₹ 8,770.756
Total Price: ₹ 57,497.176
Antigen
Glucocorticoid Receptor
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Nr3c1
Gene Alias
cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14815, 24413, 2908
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
ChIP Assay, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
antibody with no preservative
Gene Accession No.
P04150, P06536, P06537
Gene Symbols
Nr3c1
Immunogen
Synthetic peptide corresponding to residues C(245) K P L I L P D T K P K I K D(259) of human GR.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-512 detects glucocorticoid receptor (GR) from human, mouse and rat tissues
- PA1-512 has been successfully used in Western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunofluorescence, ChIP and gel shift procedures
- By Western blot, this antibody detects an ∽97 kDa protein representing GR as well as two other unidentified proteins at ∽135 to ∽145 kDa from rat liver extract
- These cross reacting proteins are not believed to be GR or GR precursors as they do not bind [3H]dexamethasone mesylate
- Immunohistochemical staining of GR in rat hippocampus using PA1-512 results in staining primarily in the nucleus
- PA1-512 does not disrupt receptor-DNA interactions
- The PA1-512 immunogen is a synthetic peptide corresponding to residues C(245) K P L I L P D T K P K I K D(259) of human GR
- The PA1-512 immunizing peptide (Cat
- # PEP-002) is available for use in for neutralization and control experiments
- Reconstitute in 50 μL PBS to create a stock of 1 mg/mL
- Glucocorticoid Receptor (NR3C1) is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors
- Glucocorticoid Receptor can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins
- The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus
- Glucocorticoid Receptor is expressed in the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart
- Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined
- Mutations in the Glucocorticoid Receptor gene are a cause of glucocorticoid resistance, or cortisol, resistance
- Studies have shown that glucocorticoid receptor (GR) must be associated with a complex of chaperone proteins for ligand activation
- GR binds to known steroids such as dexamethasone with nanomolar affinity
Compare Similar Items
Show Difference
Antigen: Glucocorticoid Receptor
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Nr3c1
Gene Alias: cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14815, 24413, 2908
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: ChIP Assay, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: antibody with no preservative
Gene Accession No.: P04150, P06536, P06537
Gene Symbols: Nr3c1
Immunogen: Synthetic peptide corresponding to residues C(245) K P L I L P D T K P K I K D(259) of human GR.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Glucocorticoid Receptor
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Nr3c1
Gene Alias:
cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14815, 24413, 2908
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
ChIP Assay, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
antibody with no preservative
Gene Accession No.:
P04150, P06536, P06537
Gene Symbols:
Nr3c1
Immunogen:
Synthetic peptide corresponding to residues C(245) K P L I L P D T K P K I K D(259) of human GR.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: AIP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Aip
Gene Alias: AA408703; AH receptor-interacting protein; AIP; ARA9; aryl hydrocarbon receptor interacting protein; aryl-hydrocarbon receptor-interacting protein; AW476050; D19Bwg1412e; FKBP16; FKBP37; HBV X-associated protein 2; HBV-X associated protein; immunophilin homolog ARA9; Immunophilin XAP2; SMTPHN; XAP2; XAP-2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11632, 9049
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: O00170, O08915
Gene Symbols: Aip
Immunogen: Full length, bacterially expressed mouse recombinant AIP.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
AIP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Aip
Gene Alias:
AA408703; AH receptor-interacting protein; AIP; ARA9; aryl hydrocarbon receptor interacting protein; aryl-hydrocarbon receptor-interacting protein; AW476050; D19Bwg1412e; FKBP16; FKBP37; HBV X-associated protein 2; HBV-X associated protein; immunophilin homolog ARA9; Immunophilin XAP2; SMTPHN; XAP2; XAP-2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11632, 9049
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
O00170, O08915
Gene Symbols:
Aip
Immunogen:
Full length, bacterially expressed mouse recombinant AIP.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CLOCK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CLOCK
Gene Alias: 5330400M04Rik; bHLHe8; circadian locomoter output cycles kaput; circadian locomoter output cycles kaput protein; circadian locomoter output cycles protein kaput; circadian locomotor output cycles kaput; class E basic helix-loop-helix protein 8; CLOCK; clock circadian regulator; clock homolog; hCLOCK; I79_020252; KAT13D; KIAA0334; mCLOCK; rCLOCK
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100770092, 12753, 60447, 9575
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: O08785, O15516, Q9WVS9
Gene Symbols: CLOCK
Immunogen: Synthetic Peptide: S(11) S I V D R D D S S I F D G L V E E D D(30) C
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Hamster, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CLOCK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CLOCK
Gene Alias:
5330400M04Rik; bHLHe8; circadian locomoter output cycles kaput; circadian locomoter output cycles kaput protein; circadian locomoter output cycles protein kaput; circadian locomotor output cycles kaput; class E basic helix-loop-helix protein 8; CLOCK; clock circadian regulator; clock homolog; hCLOCK; I79_020252; KAT13D; KIAA0334; mCLOCK; rCLOCK
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100770092, 12753, 60447, 9575
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
O08785, O15516, Q9WVS9
Gene Symbols:
CLOCK
Immunogen:
Synthetic Peptide: S(11) S I V D R D D S S I F D G L V E E D D(30) C
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Hamster, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BMAL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Arntl
Gene Alias: Arnt3; ARNTL; ARNT-like protein 1, brain and muscle; aryl hydrocarbon receptor nuclear translocator like; aryl hydrocarbon receptor nuclear translocator-like; aryl hydrocarbon receptor nuclear translocator-like protein 1; basic-helix-loop-helix-PAS orphan MOP3; basic-helix-loop-helix-PAS protein MOP3; bHLHe5; bHLH-PAS protein JAP3; BMAL1; Bmal1 protein; BMAL1b; bmal1b'; BMAL1c; Brain and muscle ARNT-like 1; brain and muscle Arnt-like protein 1; CG8727 PA; class E basic helix-loop-helix protein 5; cycle; JAP3; LOW QUALITY PROTEIN: aryl hydrocarbon receptor nuclear translocator-like protein 1; member of PAS protein 3; member of PAS superfamily 3; MGC47515; MOP3; PAS domain-containing protein 3; PASD3; testis tissue sperm-binding protein Li 50e; tic
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100755141, 11865, 29657, 406
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: O00327, Q9EPW1, Q9WTL8
Gene Symbols: Arntl
Immunogen: Synthetic Peptide: C D(582) M I D N D Q G S S S P S(594)
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Hamster, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BMAL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Arntl
Gene Alias:
Arnt3; ARNTL; ARNT-like protein 1, brain and muscle; aryl hydrocarbon receptor nuclear translocator like; aryl hydrocarbon receptor nuclear translocator-like; aryl hydrocarbon receptor nuclear translocator-like protein 1; basic-helix-loop-helix-PAS orphan MOP3; basic-helix-loop-helix-PAS protein MOP3; bHLHe5; bHLH-PAS protein JAP3; BMAL1; Bmal1 protein; BMAL1b; bmal1b'; BMAL1c; Brain and muscle ARNT-like 1; brain and muscle Arnt-like protein 1; CG8727 PA; class E basic helix-loop-helix protein 5; cycle; JAP3; LOW QUALITY PROTEIN: aryl hydrocarbon receptor nuclear translocator-like protein 1; member of PAS protein 3; member of PAS superfamily 3; MGC47515; MOP3; PAS domain-containing protein 3; PASD3; testis tissue sperm-binding protein Li 50e; tic
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100755141, 11865, 29657, 406
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
O00327, Q9EPW1, Q9WTL8
Gene Symbols:
Arntl
Immunogen:
Synthetic Peptide: C D(582) M I D N D Q G S S S P S(594)
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Hamster, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG