PA3514

Glucocorticoid Receptor beta Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA3514-Each-of-1 In Stock ₹ 44,619.54

PA3514 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

Glucocorticoid Receptor beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NR3C1

Gene Alias

GCCR; GCR; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; GR; GR Beta; GRL; NR3C1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Host Species

Rabbit

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum diluted in PBS with 0.05% sodium azide

Gene Accession No.

P04150

Gene Symbols

NR3C1

Immunogen

Synthetic Peptide: N(728) V M W L K P E S T S H T L I(742) C

Regulatory Status

RUO

Gene ID (Entrez)

2908

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • PA3-514 detects glucocorticoid receptor (GR) beta from human cells
  • PA3-514 has been successfully used in Western blot, immunocytochemistry and immunoprecipitation procedures
  • By Western blot, this antibody detects a ∽90 kDa protein representing GR beta from HeLa cell lysate
  • Immunocytochemical staining of GR beta in HeLa cells with PA3-514 results in nuclear staining
  • PA3-514 immunizing peptide corresponds to amino acid residues 728-742 from human GR beta
  • This peptide (Cat
  • # PEP-222) is available for use in neutralization and control experiments
  • Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism, and the immune and inflammatory responses
  • These compounds exert their effect through their interaction with the glucocorticoid receptor (GR) and that complex's subsequent association with DNA
  • All normal mammalian tissues examined to date have been shown to contain GR
  • The human GR exists in two forms, alpha and beta, which are thought to be the result of alternative splicing of a single gene
  • Sequence analysis indicates that the alpha and beta forms of human GR are 777 and 742 amino acids long, respectively
  • They are identical up to residue 727, after which they diverge
  • After ligand binding, the 94 kDa GR alpha isoform has been observed to translocate from the cytoplasm to the nucleus where it regulates gene expression
  • In contrast, the 90 kDa GR beta isoform does not appear to bind either glucocorticoid agonists or antagonists, and has been localized predominantly in the nucleus independent of hormone treatment in some human cell lines
  • Studies suggest that human GR beta might function as a dominant negative inhibitor of GR alpha activity.

Compare Similar Items

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Thermo Scientific

PA3514

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Antigen:
Glucocorticoid Receptor beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NR3C1

Gene Alias:
GCCR; GCR; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; GR; GR Beta; GRL; NR3C1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum diluted in PBS with 0.05% sodium azide

Gene Accession No.:
P04150

Gene Symbols:
NR3C1

Immunogen:
Synthetic Peptide: N(728) V M W L K P E S T S H T L I(742) C

Regulatory Status:
RUO

Gene ID (Entrez):
2908

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA3753

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Antigen:
PRDX4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRDX4

Gene Alias:
Antioxidant enzyme AOE372; AOE372; AOE37-2; EC 1.11.1.15; epididymis secretory sperm binding protein Li 97n; HEL-S-97n; peroxiredoxin 4; peroxiredoxin IV; Peroxiredoxin-4; Prdx4; Prx 4; Prx IV; Prx4; PRX-4; prx-IV; Rno2CysPrx04; Thioredoxin dependent peroxide reductase A0372; thioredoxin peroxidase (antioxidant enzyme); thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372; TRANK

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q13162

Gene Symbols:
PRDX4

Immunogen:
Purified human recombinant Peroxiredoxin 4.

Regulatory Status:
RUO

Gene ID (Entrez):
10549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA3821A

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Antigen:
PPAR gamma

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPARG

Gene Alias:
CIMT1; GLM1; HUMPPARG; NR1C3; nuclear hormone receptor; nuclear hormone receptor; PPARG; Nuclear receptor subfamily 1 group C member 3; nuclear receptor transcription factor; OTTHUMP00000185032; OTTHUMP00000185036; peroxisome proliferative activated receptor, gamma; peroxisome proliferative activated receptor, gamma-2; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor gamma; peroxisome proliferator activated receptor gamma 1; peroxisome proliferator activated receptor gamma 2; peroxisome proliferator activated receptor gamma 4; peroxisome proliferator activated receptor gamma-1; peroxisome proliferator activated receptor gamma-2; peroxisome proliferator activatived receptor gamma; peroxisome proliferator activator receptor, gamma; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor; peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma 1; peroxisome proliferator-activated receptor gamma 1a; peroxisome proliferator-activated receptor gamma 1-a; peroxisome proliferator-activated receptor gamma 1b; peroxisome proliferator-activated receptor gamma 1-b; peroxisome proliferator-activated receptor gamma 1c; peroxisome proliferator-activated receptor gamma 1d; peroxisome proliferator-activated receptor gamma 2; peroxisome proliferator-activated receptor-gamma; peroxisome proliferator-activated receptor-gamma 2; peroxisome proliferator-cctivated receptor gamma 1; PPAR gamma; PPAR gamma 1; PPAR gamma 3; Pparg; PPARG1; PPARG2; PPARgamma; PPAR-gamma; PPARgamma2; PPAR-gamma2; PPARy; proliferator activated gamma; transcription factor

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
O88275, P37231, P37238

Gene Symbols:
PPARG

Immunogen:
Synthetic peptide corresponding to residues M(284) M G E D K I K F K H I T P L(298) of mouse PPAR gamma 2.

Regulatory Status:
RUO

Gene ID (Entrez):
19016, 25664, 5468

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA3840

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Antigen:
mDIC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC25A10

Gene Alias:
DIC; dicarboxylate ion carrier; dicarboxylate transporter), member 10; mitochondrial dicarboxylate carrier; Slc25a10; solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 10; solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10; solute carrier family 25 member 10

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q9QZD8, Q9UBX3

Gene Symbols:
SLC25A10

Immunogen:
Synthetic peptide corresponding to the C-terminal residues L(276) R K H F G I K V P T T(287) of mDIC.

Regulatory Status:
RUO

Gene ID (Entrez):
1468, 27376

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid