P133GBT50
RANKL (soluble) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | P133GBT50-Each-of-1 | In Stock | ₹ 24,812.40 |
P133GBT50 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,812.40
GST (18%): ₹ 4,466.232
Total Price: ₹ 29,278.632
Antigen
RANKL (soluble)
Classification
Polyclonal
Conjugate
Biotin
Gene Alias
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Immunogen
E.coli-derived, 20.0 kDa Recombinant Human sRANK Ligand
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Applications
ELISA, Western Blot
Concentration
0.1-1.0 mg/mL
Formulation
PBS with no preservative
Gene Symbols
TNFSF11
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8600
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MEKAMVDGSW LDLAKRSKLE AQPFAHLTIN ATDIPSGSHK VSLSSWYHDR GWAKISNMTF SNGKLIVNQD GFYYLYANIC FRHHETSGDL ATEYLQLMVY VTKTSIKIPS SHTLMKGGST KYWSGNSEFH FYSINVGGFF KLRSGEEISI EVSNPSLLDP DQDATYFGAF KVRDID
- Preparation: Produced from sera of goats immunized with highly pure Recombinant Human sRANK Ligand
- Anti-Human sRANK Ligand-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Human sRANK Ligand by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human sRANK Ligand (500-P133G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human sRANK Ligand
- Western Blot: To detect hsRANKL by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant hsRANKL is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P133GBT-1MG will be provided as 2 x 500 μg This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation
- This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response
- T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss
- This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis
- Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts
- The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy
- Two alternatively spliced transcript variants have been found.
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Antigen: RANKL (soluble)
Classification: Polyclonal
Conjugate: Biotin
Gene Alias: CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Immunogen: E.coli-derived, 20.0 kDa Recombinant Human sRANK Ligand
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Applications: ELISA, Western Blot
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Symbols: TNFSF11
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8600
Content And Storage: -20°C
Antigen:
RANKL (soluble)
Classification:
Polyclonal
Conjugate:
Biotin
Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Immunogen:
E.coli-derived, 20.0 kDa Recombinant Human sRANK Ligand
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Applications:
ELISA, Western Blot
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Symbols:
TNFSF11
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8600
Content And Storage:
-20°C
Antigen: __
Classification: __
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Antigen: TWEAK
Classification: Polyclonal
Conjugate: Biotin
Gene Alias: APO3 ligand; APO3/DR3 ligand; APO3L; Dr3l; Dr3lg; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 12; MGC129581; MGC20669; TNF superfamily member 12; TNF-related weak inducer of apoptosis; TNFSF12; TNLG4A; tumor necrosis factor (ligand) superfamily member 12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form; tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207; zgc:153941
Immunogen: E.coli-derived, 17.0 kDa Recombinant Human TWEAK
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Human
Applications: ELISA, Western Blot
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Symbols: Tnfsf12
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8742
Content And Storage: -20°C
Antigen:
TWEAK
Classification:
Polyclonal
Conjugate:
Biotin
Gene Alias:
APO3 ligand; APO3/DR3 ligand; APO3L; Dr3l; Dr3lg; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 12; MGC129581; MGC20669; TNF superfamily member 12; TNF-related weak inducer of apoptosis; TNFSF12; TNLG4A; tumor necrosis factor (ligand) superfamily member 12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form; tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207; zgc:153941
Immunogen:
E.coli-derived, 17.0 kDa Recombinant Human TWEAK
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Human
Applications:
ELISA, Western Blot
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Symbols:
Tnfsf12
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8742
Content And Storage:
-20°C