PA1-059

Adiponectin Receptor 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1-059-Each-of-1 In Stock ₹ 46,074.06

PA1-059 - Each of 1

₹ 46,074.06

In Stock

Quantity

1

Base Price: ₹ 46,074.06

GST (18%): ₹ 8,293.331

Total Price: ₹ 54,367.391

Antigen

Adiponectin Receptor 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ADIPOR1

Gene Alias

2810031L11Rik; ACDCR1; adiponectin receptor 1; adiponectin receptor protein 1; Adipor1; CGI45; CGI-45; PAQR1; Parq1; Progestin and adipoQ receptor family member 1; Progestin and adipoQ receptor family member I; TESBP1A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

289036, 51094

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

Q96A54

Gene Symbols

ADIPOR1

Immunogen

Synthetic peptide corresponding to residues R(20) E A D T V E L A E L G P L L E E K(37) of human Adiponectin Receptor 1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-059 detects human and rat adiponectin receptor 1
  • PA1-059 has been successfully used in Western blot procedures
  • By Western blot, this antibody detects an ∽42 kDa protein corresponding to human adiponectin receptor 1 from transfected hepatocytes
  • The PA1-059 immunogen is a synthetic peptide corresponding to residues R(20) E A D T V E L A E L G P L L E E K(37) of human Adiponectin Receptor 1
  • Adiponectin (also known as 30- kDa adipocyte complement-related protein; Acrp30) is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine
  • Levels of adiponectin in the blood are decreased under conditions of obesity, insulin resistance and type 2 diabetes
  • Administration of adiponectin causes glucose-lowering effects and ameliorates insulin resistance in mice
  • Conversely, adiponectin-deficient mice exhibit insulin resistance and diabetes
  • This insulin-sensitizing effect of adiponectin seems to be mediated by an increase in fatty-acid oxidation through activation of AMP kinase and PPAR-
  • Here we report the cloning of complementary DNAs encoding adiponectin receptors 1 and 2 (AdipoR1 and AdipoR2) by expression cloning
  • AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver
  • These two adiponectin receptors are predicted to contain seven transmembrane domains, but are structurally and functionally distinct from G-protein-coupled receptors
  • Expression of AdipoR1/R2 or suppression of AdipoR1/R2 expression by small-interfering RNA supports our conclusion that they serve as receptors for globular and full-length adiponectin, and that they mediate increased AMP kinase and PPAR- ligand activities, as well as fatty-acid oxidation and glucose uptake by adiponectin.

Compare Similar Items

Show Difference

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Thermo Scientific

PA1-059

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Antigen:
Adiponectin Receptor 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADIPOR1

Gene Alias:
2810031L11Rik; ACDCR1; adiponectin receptor 1; adiponectin receptor protein 1; Adipor1; CGI45; CGI-45; PAQR1; Parq1; Progestin and adipoQ receptor family member 1; Progestin and adipoQ receptor family member I; TESBP1A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
289036, 51094

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q96A54

Gene Symbols:
ADIPOR1

Immunogen:
Synthetic peptide corresponding to residues R(20) E A D T V E L A E L G P L L E E K(37) of human Adiponectin Receptor 1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PA1-1046

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Antigen:
Ghrelin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GHRL

Gene Alias:
2210006E23Rik; AMCBX1; Appetite-regulating hormone; appetite-regulating hormone; uncharacterized protein LOC58991; exon 2- and 3-deleted preproghrelin; exon 2-deleted preproghrelin; FIP3; FIP-3; Fip3p; Ghr; Ghrelin; ghrelin 27; ghrelin 28; ghrelin and obestatin prepropeptide; ghrelin precursor; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin; ghrelin/obestatin preprohormone; ghrelin/obestatin prepropeptide; Ghrelin-27; Ghrelin-28; ghrelin-like protein; GHRL; Growth hormone secretagogue; growth hormone-releasing peptide; IKK-gamma; In2c-preproghrelin; IP; IP1; IP2; IPD2; m46; Motilin-related peptide; MTLRP; MTLRPAP; NEMO; Obestatin; Obestatin-13; Obestatin-23; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; prepro-appetite regulatory hormone; preproghrelin; proghrelin; Protein M46; UNQ524/PRO1066

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51738

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q9UBU3

Gene Symbols:
GHRL

Immunogen:
Synthetic peptide corresponding to residues G(1) S S F L S P E H Q R V Q Q R K E S K K P P A K L P Q R(28) of human GHRL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA1-1110

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Antigen:
EGFR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EGFR

Gene Alias:
2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13649, 1956, 24329

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P00533, Q01279

Gene Symbols:
EGFR

Immunogen:
Synthetic peptide corresponding to residues C L(1198) R V A P Q S S E F I G A(1210) of human EGFR.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PA1-2010

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Antigen:
APH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APH1A

Gene Alias:
6530402N02Rik; anterior pharynx defective 1 homolog A; anterior pharynx defective 1a homolog; anterior pharynx defective 1a homolog (C. elegans); APH1; APH-1; aph-1 homolog A, gamma secretase subunit; aph-1 homolog A, gamma-secretase subunit; Aph1a; APH-1a; APH1A gamma secretase subunit; Aph-1alpha; CGI-78; Gamma-secretase subunit APH-1A; hypothetical protein LOC539247; presenilin-stabilization factor; PSF; RGD1311546; RP4-790G17.3; UNQ579/PRO1141

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
226548, 51107

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
0.69 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.005% sodium azide

Gene Accession No.:
Q8BVF7, Q96BI3

Gene Symbols:
APH1A

Immunogen:
Synthetic peptide, KLH conjugated, corresponding to residues C (245) R R Q E D S R V M V Y S A L R I P P E D (265) of human APH-1aL/CT.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG