PA1330

LXR alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA1330-Each-of-1 In Stock ₹ 44,619.54

PA1330 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

LXR alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NR1H3

Gene Alias

AU018371; liver X nuclear receptor alpha variant 1; liver X receptor alpha; LXR; LXR alpha; Lxra; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10062

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

Q13133

Gene Symbols

NR1H3

Immunogen

Synthetic peptide corresponding to residues C D(318) F S Y N R E D F A K A(329) of human LXR alpha.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-330 detects recombinant human liver X receptor (LXR) alpha
  • This antibody does not detect human recombinant LXR beta protein
  • PA1-330 has been successfully used in ICC/IF and Western blot procedures
  • By Western blot, this antibody detects an ∽64 kDa protein representing recombinant human LXR alpha
  • The PA1-330 immunogen is a synthetic peptide corresponding to residues C D(318) F S Y N R E D F A K A(329) of human LXR alpha
  • The PA1-330 immunizing peptide (Cat
  • # PEP-114) is available for use in neutralization and control experiments
  • NR1H3 (oxysterols receptor LXR-alpha) is a nuclear receptor that exhibits a ligand-dependent transcriptional activation activity
  • Its interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES
  • LXRES are DR4-type response elements characterized by direct repeats of two similar hexanucleotide half-sites spaced by four nucleotides
  • NR1H3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR, and LRP8
  • It also interplays functionally with RORA for the regulation of genes involves in liver metabolism.

Compare Similar Items

Show Difference

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Thermo Scientific

PA1330

--


Antigen:
LXR alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NR1H3

Gene Alias:
AU018371; liver X nuclear receptor alpha variant 1; liver X receptor alpha; LXR; LXR alpha; Lxra; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10062

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q13133

Gene Symbols:
NR1H3

Immunogen:
Synthetic peptide corresponding to residues C D(318) F S Y N R E D F A K A(329) of human LXR alpha.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA133133

--


Antigen:
T7 Tag

Classification:
Polyclonal

Conjugate:
HRP

Gene:
__

Gene Alias:
MASMTGGQQMG; T7 cleavage

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
50mM HEPES with 0.002% thimerosal; pH 7.0

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
T7 epitope tag conjugated to KLH.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Tag

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA133156

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Antigen:
GPR56

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADGRG1

Gene Alias:
7-transmembrane protein with no EGF-like N-terminal domains-1; Adgrg1; ADGRG1 CT; ADGRG1 C-terminal fragment; ADGRG1 NT; ADGRG1 N-terminal fragment; ADGRG1-CT; adhesion G protein-coupled receptor G1; adhesion G-protein coupled receptor G1; BFPP; BPPR; Cyt28; DKFZp781L1398; G protein-coupled receptor 56; Gpr56; GPR56 7TM; GPR56 CT; GPR56 C-terminal fragment; GPR56 extracellular subunit; GPR56 NT; GPR56 N-terminal fragment; GPR56 seven-transmembrane subunit; GPR56 subunit alpha; GPR56 subunit beta; G-protein coupled receptor 56; Protein TM7XN1; secretin receptor; serpentine receptor cyt28; testicular tissue protein Li 77; TM7LN4; TM7XN1; UNQ540/PRO1083

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9289

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q9Y653

Gene Symbols:
ADGRG1

Immunogen:
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GPR56

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PA133173

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Antigen:
GPRC5D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GPRC5D

Gene Alias:
G protein-coupled receptor class C group 5 member D; G protein-coupled receptor, class C, group 5, member D; G protein-coupled receptor, family C, group 5, member D; Gprc5d; G-protein coupled receptor family C group 5 member D; MGC129713; MGC129714; orphan G-protein coupled receptor; RGD1563887

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55507

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q9NZD1

Gene Symbols:
GPRC5D

Immunogen:
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human GPRC5D

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG