MA1-413

Phospho-Progesterone Receptor (Ser190) Monoclonal Antibody (1154), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA1-413-Each-of-1 In Stock ₹ 45,902.94

MA1-413 - Each of 1

₹ 45,902.94

In Stock

Quantity

1

Base Price: ₹ 45,902.94

GST (18%): ₹ 8,262.529

Total Price: ₹ 54,165.469

Antigen

Phospho-Progesterone Receptor (Ser190)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

antibody with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P06401

Gene Symbols

PGR

Immunogen

Synthetic phosphopeptide corresponding to residues V(184) L P R G L S(p) P A R Q L L(196) of human Progesterone Receptor.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

1154

Conjugate

Unconjugated

Gene

PGR

Gene Alias

9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

5241

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-413 detects phospho-progesterone receptor (pSer190) from human samples
  • MA1-413 has been successfully used in Western blot, immunohistochemistry, ELISA, immunofluorescence, and immunoprecipitation procedures
  • By Western blot, this antibody detects ∽81 and ∽116 kDa proteins representing phospho-progesterone receptor (pSer190) A and B from T47D cell and human breast carcinoma extracts
  • Immunohistochemical staining of phospho-progesterone receptor (pSer190) (paraffin samples) can be performed using MA1-413
  • The MA1-413 immunogen is a synthetic peptide corresponding to residues V(184) L P R G L S(p) P A R Q L L(196) of human Progesterone Receptor
  • The progesterone receptor (PR) is a member of the steroid family of nuclear receptors
  • The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy
  • PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites
  • PR-B is the transcriptionally active form and is responsible for activating genes for the maintenance of the endometrium, maintenance of pregnancy, and inhibition of ovulation
  • PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus
  • This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity
  • In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins
  • Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription
  • A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.

Compare Similar Items

Show Difference

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Thermo Scientific

MA1-413

--


Antigen:
Phospho-Progesterone Receptor (Ser190)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
antibody with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Synthetic phosphopeptide corresponding to residues V(184) L P R G L S(p) P A R Q L L(196) of human Progesterone Receptor.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
1154

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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MA1-752

--


Antigen:
Presenilin 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P49768, P49769, P97887

Gene Symbols:
PSEN1

Immunogen:
Synthetic peptide corresponding to residues C S(313) K Y N A E S T E R E S Q D T V A E N D D G(334) of humen PS1.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
APS 18

Conjugate:
Unconjugated

Gene:
PSEN1

Gene Alias:
AD3; Ad3h; Alzheimer Disease 3; FAD; Minilin; presenilin 1; presenilin 1 (Alzheimer disease 3); presenilin1; presenilin-1; Presenilin-1 CTF subunit; Presenilin-1 CTF12; Presenilin-1 NTF subunit; Protein S182; PS1; PS-1; PS1-CTF12; PSEN1; Psnl1; S182; S182 protein; Senilin 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
19164, 29192, 5663

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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MA1-754

--


Antigen:
PSEN2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
O88777, P49810, Q61144

Gene Symbols:
PSEN2

Immunogen:
Synthetic peptide corresponding to residues C L(317) P Y D P E M E E D S Y D S F G E P(334) of human PS2.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
APS 26

Conjugate:
Unconjugated

Gene:
PSEN2

Gene Alias:
AD3L; AD3LP; AD4; Ad4h; AD5; Alg3; ALG-3; Alzheimer disease 4; CMD1V; E5-1; presenilin 2; presenilin-2; Presenilin-2 CTF subunit; Presenilin-2 NTF subunit; PS2; Ps-2; PSEN 2; PSEN2; Psnl2; STM2; STM-2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
19165, 5664, 81751

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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MA1-861

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Antigen:
ErbB4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q15303, Q61527

Gene Symbols:
ERBB4

Immunogen:
Synthetic Peptide: C R(1250) S T L Q H P D Y L Q E Y S T(1264)

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
HFR1

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; Her4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13869, 2066

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid