PA1110

Androgen Receptor Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1110-Each-of-1 In Stock ₹ 50,822.64

PA1110 - Each of 1

₹ 50,822.64

In Stock

Quantity

1

Base Price: ₹ 50,822.64

GST (18%): ₹ 9,148.075

Total Price: ₹ 59,970.715

Antigen

Androgen Receptor

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AR

Gene Alias

AIS; Andr; androgen nuclear receptor variant 2; androgen receptor; androgen receptor (Testicular feminization), same as Tfm; androgen receptor splice variant 4b; Ar; AR8; AR-A; AW320017; DHTR; dihydrotestosterone receptor; HUMARA; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; RP11-383C12.1; SBMA; SMAX1; TFM; Variant AR45

Host Species

Rabbit

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum diluted in PBS with 0.05% sodium azide

Gene Accession No.

P10275, P15207, P19091

Gene Symbols

AR

Immunogen

Fusion protein containing residues 331-572 of human androgen receptor.

Regulatory Status

RUO

Gene ID (Entrez)

11835, 24208, 367

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • PA1-110 detects androgen receptor (AR) from human, primate, rat, and mouse tissues
  • This antibody does not detect estrogen, progesterone, or glucocorticoid receptors
  • PA1-110 has been successfully used in Western blot, immunocytochemistry, immunohistochemistry and immunoprecipitation procedures
  • By Western blot, this antibody detects an ∽110 kDa protein representing AR from rat brain homogenate
  • Immunohistochemical staining of AR in rat brain with PA1-110 results in intense nuclear staining
  • For fixation of frozen sections, 2% paraformaldehyde + 15% picric acid solution in phosphate buffer, pH 7.4 is recommended
  • The PA1-110 immunogen is a fusion protein containing residues 331-572 of human androgen receptor
  • The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors
  • The receptor is more than 90 kDa and has three major functional domains: the N-terminal domain, DNA-binding domain, and the androgen-binding domain
  • The androgen receptor is a ligand-activated transcription factor that binds active testosterone (T) and dihydrotestosterone (DHT)
  • Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes
  • The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis
  • AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and brain
  • Androgen Receptor is a phosphoprotein, and also regulates mitogen-activated protein kinase (MAP kinase)
  • The inhibition of the MEK1/2 pathway correlates directly with a change in phosphorylation state of the androgen receptor
  • Abnormalities in the AR signaling pathway have been linked to a number of diseases, including prostate cancer, Kennedy's disease, and male infertility
  • Mutations in this gene are associated with complete androgen insensitivity (CAIS).

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Show Difference

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PA1110

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Antigen:
Androgen Receptor

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AR

Gene Alias:
AIS; Andr; androgen nuclear receptor variant 2; androgen receptor; androgen receptor (Testicular feminization), same as Tfm; androgen receptor splice variant 4b; Ar; AR8; AR-A; AW320017; DHTR; dihydrotestosterone receptor; HUMARA; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; RP11-383C12.1; SBMA; SMAX1; TFM; Variant AR45

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum diluted in PBS with 0.05% sodium azide

Gene Accession No.:
P10275, P15207, P19091

Gene Symbols:
AR

Immunogen:
Fusion protein containing residues 331-572 of human androgen receptor.

Regulatory Status:
RUO

Gene ID (Entrez):
11835, 24208, 367

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PA11100

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Antigen:
CPEB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CPEB1

Gene Alias:
AU024112; CEBP; Cpeb; CPEB1; CPEB-1; CPE-binding protein 1; CPE-BP1; cytoplasmic polyadenylation element binding protein 1; cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; h-CPEB; hCPEB-1; mCPEB; mCPEB-1; MGC34136; MGC60106

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P0C279, P70166, Q9BZB8

Gene Symbols:
CPEB1

Immunogen:
Synthetic peptide corresponding to residues C H(545) S M E G L R H H S P L M R N Q K N(562) of human CPEB.

Regulatory Status:
RUO

Gene ID (Entrez):
12877, 293056, 64506

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PA1121

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Antigen:
GnRH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GNRH1

Gene Alias:
Gnrh; Gnrh1; Gnrh2; Gnrha; GnRH-associated peptide 1; GnRH-associated peptide I; GnRH-I; Gonadoliberin I; Gonadoliberin-1; Gonadorelin; gonadotropin releasing hormone 1; gonadotropin releasing hormone 2; gonadotropin-releasing hormone 1 (luteinizing-releasing hormone); gonadotropin-releasing hormone 1 variant A; gonadotropin-releasing hormone 1 variant B; Gonadotropin-releasing hormone I; GRH; hpg; hypogonadal; leuteinizing-releasing hormone; LHRH; LH-RH I; Lhrh1; LNRH; Luliberin I; luteinizing hormone releasing hormone; luteinizing hormone-releasing hormone; luteinizing hormone-releasing hormone I; Lutropin; Progonadoliberin I; progonadoliberin-1; prolactin release-inhibiting factor; Prolactin release-inhibiting factor 1; Prolactin release-inhibiting factor I; Rgnrhg1

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Amphibian, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P13562

Gene Symbols:
GNRH1

Immunogen:
Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH.

Regulatory Status:
RUO

Gene ID (Entrez):
14714

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PA1122

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Antigen:
GnRH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GNRH1

Gene Alias:
Gnrh; Gnrh1; Gnrh2; Gnrha; GnRH-associated peptide 1; GnRH-associated peptide I; GnRH-I; Gonadoliberin I; Gonadoliberin-1; Gonadorelin; gonadotropin releasing hormone 1; gonadotropin releasing hormone 2; gonadotropin-releasing hormone 1 (luteinizing-releasing hormone); gonadotropin-releasing hormone 1 variant A; gonadotropin-releasing hormone 1 variant B; Gonadotropin-releasing hormone I; GRH; hpg; hypogonadal; leuteinizing-releasing hormone; LHRH; LH-RH I; Lhrh1; LNRH; Luliberin I; luteinizing hormone releasing hormone; luteinizing hormone-releasing hormone; luteinizing hormone-releasing hormone I; Lutropin; Progonadoliberin I; progonadoliberin-1; prolactin release-inhibiting factor; Prolactin release-inhibiting factor 1; Prolactin release-inhibiting factor I; Rgnrhg1

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Frozen)

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P13562

Gene Symbols:
GNRH1

Immunogen:
Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH.

Regulatory Status:
RUO

Gene ID (Entrez):
14714

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid