MA1412

Progesterone Receptor Monoclonal Antibody (alpha PR-22), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA1412-Each-of-1 In Stock ₹ 44,448.42

MA1412 - Each of 1

₹ 44,448.42

In Stock

Quantity

1

Base Price: ₹ 44,448.42

GST (18%): ₹ 8,000.716

Total Price: ₹ 52,449.136

Antigen

Progesterone Receptor

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P06401, P07812

Gene Symbols

PGR

Immunogen

Progesterone receptor purified from chick oviduct cytosol.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Chicken, Human, Reptile

Product Type

Antibody

Isotype

IgG2b

Applications

Gel Shift, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

alpha PR-22

Conjugate

Unconjugated

Gene

PGR

Gene Alias

9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

396198, 5241

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

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Description

  • MA1-412 detects the A and B forms of progesterone receptor from chicken and some species of turtles
  • This antibody does not cross-react with estrogen receptor or glucocorticoid receptor
  • MA1-412 has been successfully used in Western blot and immunoprecipitation procedures
  • By Western blot, this antibody detects a 78 kDa protein representing the A form and a 110 kDa protein representing the B form of PR
  • The proportion of receptor bound by this product is significantly greater than catalog number MA1-411 due to the binding of both the A and B form of PR
  • Protein A can effectively be used with this product in immunoprecipitation experiments
  • MA1-412 detects the A and B forms of progesterone receptor from human, chicken and some species of turtles
  • This antibody does not cross-react with estrogen receptor or glucocorticoid receptor
  • The MA1-412 immunogen is progesterone receptor purified from chick oviduct cytosol
  • Reconstitute with PBS
  • The progesterone receptor (PR) is a member of the steroid family of nuclear receptors
  • The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy
  • PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites
  • PR-B is the transcriptionally active form and is responsible for activating genes for the maintenance of the endometrium, maintenance of pregnancy, and inhibition of ovulation
  • PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus
  • This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity
  • In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins
  • Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription
  • A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.

Compare Similar Items

Show Difference

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Thermo Scientific

MA1412

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Antigen:
Progesterone Receptor

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P06401, P07812

Gene Symbols:
PGR

Immunogen:
Progesterone receptor purified from chick oviduct cytosol.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Reptile

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Gel Shift, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
alpha PR-22

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
396198, 5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

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MA143011

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Antigen:
Factor VII

Classification:
Monoclonal

Concentration:
14.1 mg/mL

Formulation:
50% water with 50% glycerol and no preservative

Gene Accession No.:
P08709

Gene Symbols:
F7

Immunogen:
Human factor VII/VIIa.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Radioimmune Assays (RIA), Western Blot

Clone:
5031

Conjugate:
Unconjugated

Gene:
F7

Gene Alias:
AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA

Host Species:
Mouse

Purification Method:
Ammonium sulfate precipitation, Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2155

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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MA143012

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Antigen:
Factor IX

Classification:
Monoclonal

Concentration:
9.5 mg/mL

Formulation:
50% water with 50% glycerol and no preservative

Gene Accession No.:
P00740

Gene Symbols:
F9

Immunogen:
Heavy chain of human factor IX and Ixa.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry, Radioimmune Assays (RIA), Western Blot

Clone:
5041

Conjugate:
Unconjugated

Gene:
F9

Gene Alias:
AW111646; Cf9; Cf-9; Christmas factor; coagulation factor 9; coagulation factor IX; coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B); Coagulation factor IXa heavy chain; Coagulation factor IXa light chain; EC 3.4.21.22; F9; F9 p22; factor 9; factor IX (Christmas factor) precursor; factor IX F9; Factor9; FIX; FIX F9; HEMB; P19; plasma thromboplastic component; plasma thromboplastin component; PTC; RP6-88D7.1; serine protease; THPH8

Host Species:
Mouse

Purification Method:
Affinity chromatography, Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
2158

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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MA143013

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Antigen:
Factor X/Xa

Classification:
Monoclonal

Concentration:
7.6 mg/mL

Formulation:
50% water with 50% glycerol and no preservative

Gene Accession No.:
P00742

Gene Symbols:
F10

Immunogen:
Purified human Factor X

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Affinity Purification, ELISA, Inhibition Assays, Radioimmune Assays (RIA), Western Blot

Clone:
5050

Conjugate:
Unconjugated

Gene:
F10

Gene Alias:
Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
2159

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid