MA1510
Glucocorticoid Receptor Monoclonal Antibody (BuGR2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA1510-Each-of-1 | In Stock | ₹ 47,614.14 |
MA1510 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
Glucocorticoid Receptor
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide; pH 7.2
Gene Accession No.
P04150, P06536, P06537, P35547, P49115, P59667
Gene Symbols
Nr3c1
Immunogen
Partially purified rat GR.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Guinea Pig, Human, Mouse, Ovine, Rabbit, Rat, Yeast
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone
BuGR2
Conjugate
Unconjugated
Gene
Nr3c1
Gene Alias
cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
100008890, 100135583, 14815, 24413, 2908, 443412
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Related Products
Description
- MA1-510 detects glucocorticoid receptor (GR) from human, mouse, rat, guinea pig, rabbit, sheep and yeast samples
- This antibody does not react with primate, avian or amphibian GR
- MA1-510 has been successfully used in Western blot, immunofluorescence, immunocytochemistry, flow cytometry, immunohistochemistry, immunoprecipitation, and gel shift procedures
- By Western blot, this antibody detects a 97 kDa protein representing GR in L929 cell extract
- Immunocytochemical staining of GR in L929 cells with MA1-510 results in staining of both the cytoplasm and nucleus, even in the presence of hormone
- Using enzymatic digestion analysis, MA1-510 reacts with the undigested 97 kDa GR, a 17 kDa DNA-binding trypsin fragment, and a 45 kDa steroid- and DNA-binding chymotrypsin fragment
- The MA1-510 immunogen is partially purified rat GR
- Reconstitute with 100 μL distilled water
- Glucocorticoid Receptor (NR3C1) is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors
- Glucocorticoid Receptor can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins
- The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus
- Glucocorticoid Receptor is expressed in the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart
- Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined
- Mutations in the Glucocorticoid Receptor gene are a cause of glucocorticoid resistance, or cortisol, resistance
- Studies have shown that glucocorticoid receptor (GR) must be associated with a complex of chaperone proteins for ligand activation
- GR binds to known steroids such as dexamethasone with nanomolar affinity
Compare Similar Items
Show Difference
Antigen: Glucocorticoid Receptor
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide; pH 7.2
Gene Accession No.: P04150, P06536, P06537, P35547, P49115, P59667
Gene Symbols: Nr3c1
Immunogen: Partially purified rat GR.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Guinea Pig, Human, Mouse, Ovine, Rabbit, Rat, Yeast
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone: BuGR2
Conjugate: Unconjugated
Gene: Nr3c1
Gene Alias: cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 100008890, 100135583, 14815, 24413, 2908, 443412
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Antigen:
Glucocorticoid Receptor
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide; pH 7.2
Gene Accession No.:
P04150, P06536, P06537, P35547, P49115, P59667
Gene Symbols:
Nr3c1
Immunogen:
Partially purified rat GR.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Guinea Pig, Human, Mouse, Ovine, Rabbit, Rat, Yeast
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone:
BuGR2
Conjugate:
Unconjugated
Gene:
Nr3c1
Gene Alias:
cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
100008890, 100135583, 14815, 24413, 2908, 443412
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Antigen: AHR
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: antibody with 0.05% sodium azide
Gene Accession No.: P30561, P35869, P41738
Gene Symbols: AHR
Immunogen: Synthetic peptide corresponding to residues R(12) K R R K P(17) V(22) K P I P A E G I K(31) of mouse AhR.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG3 κ
Applications: ChIP Assay, Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: RPT9
Conjugate: Unconjugated
Gene: AHR
Gene Alias: Ah; Ah receptor; Ahh; Ahr; Ahre; AH-receptor; aromatic hydrocarbon receptor; aryl hydrocarbon receptor; aryl-hydrocarbon receptor; bHLHe76; Class E basic helix-loop-helix protein 76; dioxin receptor; In
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11622, 196, 25690
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
AHR
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
antibody with 0.05% sodium azide
Gene Accession No.:
P30561, P35869, P41738
Gene Symbols:
AHR
Immunogen:
Synthetic peptide corresponding to residues R(12) K R R K P(17) V(22) K P I P A E G I K(31) of mouse AhR.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG3 κ
Applications:
ChIP Assay, Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
RPT9
Conjugate:
Unconjugated
Gene:
AHR
Gene Alias:
Ah; Ah receptor; Ahh; Ahr; Ahre; AH-receptor; aromatic hydrocarbon receptor; aryl hydrocarbon receptor; aryl-hydrocarbon receptor; bHLHe76; Class E basic helix-loop-helix protein 76; dioxin receptor; In
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11622, 196, 25690
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Mist1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: Q7RTS1, Q9QYC3
Gene Symbols: Bhlha15
Immunogen: Mouse Mist1, C-terminus residues 175-197.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: 6E8/A12/C11P1
Conjugate: Unconjugated
Gene: Bhlha15
Gene Alias: 1810009C13Rik; basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix family member a15; basic helix-loop-helix family, member a15; Basic helix-loop-helix transcription factor (bHlH); bHlH; BHLHA15; BHLHB8; Class A basic helix-loop-helix protein 15; class B basic helix-loop-helix protein 8; class II bHLH protein MIST1; MIST1; MIST-1; Muscle, intestine and stomach expression 1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 168620, 17341
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Mist1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
Q7RTS1, Q9QYC3
Gene Symbols:
Bhlha15
Immunogen:
Mouse Mist1, C-terminus residues 175-197.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
6E8/A12/C11P1
Conjugate:
Unconjugated
Gene:
Bhlha15
Gene Alias:
1810009C13Rik; basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix family member a15; basic helix-loop-helix family, member a15; Basic helix-loop-helix transcription factor (bHlH); bHlH; BHLHA15; BHLHB8; Class A basic helix-loop-helix protein 15; class B basic helix-loop-helix protein 8; class II bHLH protein MIST1; MIST1; MIST-1; Muscle, intestine and stomach expression 1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
168620, 17341
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: RT1.D
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P18211
Gene Symbols: RT1-Db1
Immunogen: Rat spleen membrane glycoproteins depleted of Ia-A antigens
Quantity: 250 μg
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: OX-17
Conjugate: Unconjugated
Gene: RT1-Db1
Gene Alias: Db1; MHC class II RT1D beta1 chain antigen; rano class II histocompatibility antigen, D-1 beta chain; rat class I D; RT1 class II histocompatibility antigen, D-1 beta chain; RT1 class II, locus Db1; RT1-D beta; RT1-Db; RT1-Db1; RT1-Db1n
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 294270
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RT1.D
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P18211
Gene Symbols:
RT1-Db1
Immunogen:
Rat spleen membrane glycoproteins depleted of Ia-A antigens
Quantity:
250 μg
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
OX-17
Conjugate:
Unconjugated
Gene:
RT1-Db1
Gene Alias:
Db1; MHC class II RT1D beta1 chain antigen; rano class II histocompatibility antigen, D-1 beta chain; rat class I D; RT1 class II histocompatibility antigen, D-1 beta chain; RT1 class II, locus Db1; RT1-D beta; RT1-Db; RT1-Db1; RT1-Db1n
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
294270
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid