PA11060
Phospho-IRS1 (Tyr1179) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA11060-Each-of-1 | In Stock | ₹ 42,566.10 |
PA11060 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,566.10
GST (18%): ₹ 7,661.898
Total Price: ₹ 50,227.998
Antigen
Phospho-IRS1 (Tyr1179)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRS1
Gene Alias
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16367, 3667
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P35568, P35569
Gene Symbols
IRS1
Immunogen
Synthetic phosphopeptide corresponding to residues L(1173) E N G L N (pY) I D L D L V K(1186) of human IRS-1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-1060 detects phosphorylated IRS-1 (Tyr1173) in mouse and human cells
- PA1-1060 has been successfully used in Western blot procedures
- By Western blot, this antibody detects a ∽170 kDa protein representing phospho-IRS-1 (Tyr1173) from 3T3 L1 cells treated with insulin
- The PA1-1060 immunogen is a synthetic phosphopeptide corresponding to residues L(1173) E N G L N (pY) I D L D L V K(1186) of human IRS-1
- This immunogenic sequence is 100% conserved in humans and chickens and 85% and 87% conserved in rat and mouse, respectively
- The conserved phosphorylation site corresponds to residue Y1179 in human, Y1177 in chicken, Y1173 in mouse, and Y1172 in rat
- This peptide (Cat
- # PEP-205) is available for use in neutralization and control experiments
- IRS-1, a major substrate of the insulin receptor, is phosphorylated in response to stimulation of cells by insulin, insulin-like growth factor 1 (IGF-1) and interleukin 4 (IL-4)
- IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues
- An insulin-sensitive serine/threonine kinase casein kinase II mediates a portion of the insulin-stimulated serine/threonine phosphorylation of overexpressed IRS-1 in vivo
- Thr 502 is identified as the major casein kinase II-catalyzed phosphorylation site in rat IRS-1, and Ser 99 is an additional phosphorylation site catalyzed by casein kinase II
- Thus, casein kinase II-catalyzed phosphorylation of IRS-1 may be a component of the intracellular insulin signaling cascade
- IRS-1 contains three putative binding sites for 14-3-3 (Ser 270, Ser 374 and Ser 641) and the motif around Ser 270 is located in the phosphortyrosine binding domain of IRS-1, which is responsible for the interaction with the insulin receptor.
Compare Similar Items
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Antigen: Phospho-IRS1 (Tyr1179)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRS1
Gene Alias: G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16367, 3667
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P35568, P35569
Gene Symbols: IRS1
Immunogen: Synthetic phosphopeptide corresponding to residues L(1173) E N G L N (pY) I D L D L V K(1186) of human IRS-1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-IRS1 (Tyr1179)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRS1
Gene Alias:
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16367, 3667
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P35568, P35569
Gene Symbols:
IRS1
Immunogen:
Synthetic phosphopeptide corresponding to residues L(1173) E N G L N (pY) I D L D L V K(1186) of human IRS-1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Androgen Receptor
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AR
Gene Alias: AIS; Andr; androgen nuclear receptor variant 2; androgen receptor; androgen receptor (Testicular feminization), same as Tfm; androgen receptor splice variant 4b; Ar; AR8; AR-A; AW320017; DHTR; dihydrotestosterone receptor; HUMARA; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; RP11-383C12.1; SBMA; SMAX1; TFM; Variant AR45
Host Species: Rabbit
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 11835, 24208, 367
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum diluted in PBS with 0.05% sodium azide
Gene Accession No.: P10275, P15207, P19091
Gene Symbols: AR
Immunogen: Fusion protein containing residues 331-572 of human androgen receptor.
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Androgen Receptor
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AR
Gene Alias:
AIS; Andr; androgen nuclear receptor variant 2; androgen receptor; androgen receptor (Testicular feminization), same as Tfm; androgen receptor splice variant 4b; Ar; AR8; AR-A; AW320017; DHTR; dihydrotestosterone receptor; HUMARA; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; RP11-383C12.1; SBMA; SMAX1; TFM; Variant AR45
Host Species:
Rabbit
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
11835, 24208, 367
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum diluted in PBS with 0.05% sodium azide
Gene Accession No.:
P10275, P15207, P19091
Gene Symbols:
AR
Immunogen:
Fusion protein containing residues 331-572 of human androgen receptor.
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CPEB1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CPEB1
Gene Alias: AU024112; CEBP; Cpeb; CPEB1; CPEB-1; CPE-binding protein 1; CPE-BP1; cytoplasmic polyadenylation element binding protein 1; cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; h-CPEB; hCPEB-1; mCPEB; mCPEB-1; MGC34136; MGC60106
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12877, 293056, 64506
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P0C279, P70166, Q9BZB8
Gene Symbols: CPEB1
Immunogen: Synthetic peptide corresponding to residues C H(545) S M E G L R H H S P L M R N Q K N(562) of human CPEB.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CPEB1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CPEB1
Gene Alias:
AU024112; CEBP; Cpeb; CPEB1; CPEB-1; CPE-binding protein 1; CPE-BP1; cytoplasmic polyadenylation element binding protein 1; cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; h-CPEB; hCPEB-1; mCPEB; mCPEB-1; MGC34136; MGC60106
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12877, 293056, 64506
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P0C279, P70166, Q9BZB8
Gene Symbols:
CPEB1
Immunogen:
Synthetic peptide corresponding to residues C H(545) S M E G L R H H S P L M R N Q K N(562) of human CPEB.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GnRH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GNRH1
Gene Alias: Gnrh; Gnrh1; Gnrh2; Gnrha; GnRH-associated peptide 1; GnRH-associated peptide I; GnRH-I; Gonadoliberin I; Gonadoliberin-1; Gonadorelin; gonadotropin releasing hormone 1; gonadotropin releasing hormone 2; gonadotropin-releasing hormone 1 (luteinizing-releasing hormone); gonadotropin-releasing hormone 1 variant A; gonadotropin-releasing hormone 1 variant B; Gonadotropin-releasing hormone I; GRH; hpg; hypogonadal; leuteinizing-releasing hormone; LHRH; LH-RH I; Lhrh1; LNRH; Luliberin I; luteinizing hormone releasing hormone; luteinizing hormone-releasing hormone; luteinizing hormone-releasing hormone I; Lutropin; Progonadoliberin I; progonadoliberin-1; prolactin release-inhibiting factor; Prolactin release-inhibiting factor 1; Prolactin release-inhibiting factor I; Rgnrhg1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14714
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P13562
Gene Symbols: GNRH1
Immunogen: Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Amphibian, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
GnRH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GNRH1
Gene Alias:
Gnrh; Gnrh1; Gnrh2; Gnrha; GnRH-associated peptide 1; GnRH-associated peptide I; GnRH-I; Gonadoliberin I; Gonadoliberin-1; Gonadorelin; gonadotropin releasing hormone 1; gonadotropin releasing hormone 2; gonadotropin-releasing hormone 1 (luteinizing-releasing hormone); gonadotropin-releasing hormone 1 variant A; gonadotropin-releasing hormone 1 variant B; Gonadotropin-releasing hormone I; GRH; hpg; hypogonadal; leuteinizing-releasing hormone; LHRH; LH-RH I; Lhrh1; LNRH; Luliberin I; luteinizing hormone releasing hormone; luteinizing hormone-releasing hormone; luteinizing hormone-releasing hormone I; Lutropin; Progonadoliberin I; progonadoliberin-1; prolactin release-inhibiting factor; Prolactin release-inhibiting factor 1; Prolactin release-inhibiting factor I; Rgnrhg1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14714
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P13562
Gene Symbols:
GNRH1
Immunogen:
Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Amphibian, Mouse
Product Type:
Antibody
Isotype:
IgG