PA129465

APE1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA129465-Each-of-1 In Stock ₹ 47,015.22

PA129465 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

APE1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APEX1

Gene Alias

AP endonuclease 1; AP endonuclease class I; AP lyase; Ape; APE1; APEN; Apex; APEX nuclease; APEX nuclease (multifunctional DNA repair enzyme) 1; APEX nuclease 1; Apex1; apurinic/a; Apurinic/apy; apurinic/apyrimidinic (abasic) endonuclease; apurinic/apyrimidinic endodeoxyribonuclease 1; apurinic/apyrimidinic endonuclease; apurinic/apyrimidinic endonuclease 1; Apurinic-apyrimidinic endonuclease 1; APX; BAP 1; BAP1; deoxyribonuclease (apurinic or apyrimidinic); DNA-(apurinic or apyrimidinic site) endonuclease; DNA-(apurinic or apyrimidinic site) lyase; DNA-(apurinic or apyrimidinic site) lyase, mitochondrial; HAP1; protein REF-1; redox factor 1; redox factor-1; REF1; REF-1

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

328

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P27695

Gene Symbols

APEX1

Immunogen

KLH conjugated synthetic peptides corresponding to amino acids 36-52 and 216-232 of human APE.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-29465 detects APE from human samples
  • Mammalian apurinic/apyrimidinic endonuclease (APE/ref-1) is a multifunctional, bipartite enzyme that plays an important role in numerous, cellular functions
  • APE is responsible for repairing abasic sites in DNA and in regulating the redox state of other proteins that play roles in oxidative signaling, transcription factor regulation (Fos, Jun, NF-kB, Myb, HIF-1 alpha, CREB, Pax), cell cycle control (p53), and apoptosis
  • The most common form of DNA damage is the creation of abasic sites which are brought about through spontaneous loss or oxidative DNA damage, through chemically initiated hydrolysis (chemotherapy), ionizing radiation, UV irradiation, oxidizing agents, and removal of modified bases by DNA glycosylases
  • APE is differentially expressed during development and in different tissues
  • This protein has diverse subcellular localization patterns which support the possibility of its interaction with numerous, other cellular proteins in addition to DNA repair within the nucleus
  • Regulation of APE by phosphorylation is mediated, at least in part, by casein kinase II
  • Increases in APE message and protein levels are observed upon the reintroduction of oxygen to hypoxic cells, and in some malignant tissue relative to normal tissue
  • Decreases in APE expression have been associated with the induction of cellular apoptosis.

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Show Difference

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Thermo Scientific

PA129465

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Antigen:
APE1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APEX1

Gene Alias:
AP endonuclease 1; AP endonuclease class I; AP lyase; Ape; APE1; APEN; Apex; APEX nuclease; APEX nuclease (multifunctional DNA repair enzyme) 1; APEX nuclease 1; Apex1; apurinic/a; Apurinic/apy; apurinic/apyrimidinic (abasic) endonuclease; apurinic/apyrimidinic endodeoxyribonuclease 1; apurinic/apyrimidinic endonuclease; apurinic/apyrimidinic endonuclease 1; Apurinic-apyrimidinic endonuclease 1; APX; BAP 1; BAP1; deoxyribonuclease (apurinic or apyrimidinic); DNA-(apurinic or apyrimidinic site) endonuclease; DNA-(apurinic or apyrimidinic site) lyase; DNA-(apurinic or apyrimidinic site) lyase, mitochondrial; HAP1; protein REF-1; redox factor 1; redox factor-1; REF1; REF-1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
328

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P27695

Gene Symbols:
APEX1

Immunogen:
KLH conjugated synthetic peptides corresponding to amino acids 36-52 and 216-232 of human APE.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA129491

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Antigen:
LHX3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LHX3

Gene Alias:
bLhx3b; CPHD3; DKFZp762A2013; Homeobox protein LIM-3; homeobox protein P-LIM; lhx3; Lhx3b; LIM homeo box protein 3; LIM homeobox 3; LIM homeobox protein; LIM homeobox protein 3; LIM homeodomain 3; LIM homeodomain 3 protein b isoform; LIM homeodomain box protein 3; LIM homeodomain protein 3b; LIM/homeobox protein Lhx3; LIM/homeodomain protein LHX3; lim3; Lim-3; LOW QUALITY PROTEIN: LIM/homeobox protein Lhx3; M2-LHX3; mLIM3; mLim-3; Plim; P-LIM

Host Species:
Rabbit

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
16871, 170671, 8022

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Free Floating), Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.6

Gene Accession No.:
P50481, Q9UBR4

Gene Symbols:
LHX3

Immunogen:
C-terminal portion of mouse LHX3 protein.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Amphibian, Fish, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA129680

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Antigen:
Lysozyme

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LYZ

Gene Alias:
1,4-beta-N-acetylmuramidase C; 1700038F02Rik; 4-beta-N-acetylmuramidase C; AI326280; Allergen Gal d IV; bA534G20.1; c-type lysozyme; dystrophin; egg white lysozyme; Gal d 4; KAAG648; LYC2; Lys; Lysm; lysozyme; lysozyme (renal amyloidosis); lysozyme 1; lysozyme 2; lysozyme C; Lysozyme C type M; lysozyme C type P; Lysozyme C, spleen isozyme; lysozyme C-1; Lysozyme C-2; lysozyme C-3; lysozyme d1; lysozyme F1; lysozyme like 1; lysozyme-like 1; lysozyme-like protein 1; lysozyme-like protein 2; Lysz; LYZ; Lyz1; Lyz2; LYZC; LYZD1; LYZF1; LYZL1; Lyzs; Lzm; Lzm-s1; Lzp; Lzp-s; P lysozyme structural; PRO1278; renal amyloidosis; RGD1559869; unnamed protein product; UNQ648/PRO1278

Host Species:
Rabbit

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
4069

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P61626

Gene Symbols:
LYZ

Immunogen:
Purified human lysozyme from urine of patients with monocystic leukemia.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA129715

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Antigen:
Complement C3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3d; complement C3; Complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3; complement component C3 alpha-chain; complement component C3a; complement component C3b; complement component C3d; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; I79_008227; LOC100060539; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3; Unknown (protein for MGC:134562)

Host Species:
Goat

Purification Method:
Purified

Regulatory Status:
RUO

Gene ID (Entrez):
100009121, 100060539, 100135462, 100763958, 12266, 24232, 397072, 718

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunoelectrophoresis, Western Blot

Concentration:
94 mg/mL

Formulation:
0.05M tris HCl with 500mM NaCl and 0.1% sodium azide; pH 7.5

Gene Accession No.:
P01024, P01025, P01026, P01027, P12247, P12387

Gene Symbols:
C3, LOC100060539

Immunogen:
Human complement C3

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Baboon, Equine, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG