PA130399

p21 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA130399-Each-of-1 In Stock ₹ 50,822.64

PA130399 - Each of 1

₹ 50,822.64

In Stock

Quantity

1

Base Price: ₹ 50,822.64

GST (18%): ₹ 9,148.075

Total Price: ₹ 59,970.715

Antigen

p21

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDKN1A

Gene Alias

Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1026, 114851, 12575

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 0.2% gelatin and 0.1% sodium azide

Gene Accession No.

P38936, P39689

Gene Symbols

CDKN1A

Immunogen

Synthetic peptide (Human) (C terminal).

Quantity

1 mL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

MA3001

--

Img

Thermo Scientific

PA128462

--

Img

Thermo Scientific

PA130315

--

Img

Thermo Scientific

MA172519

--

Img

Thermo Scientific

MA1826

--

Img

Thermo Scientific

MA181489

--

Img

Thermo Scientific

PA139454

--

Img

Thermo Scientific

MA12023

--

Description

  • Recommended positive controls: C32
  • Protein p21 is a tumor suppressor protein which is an inhibitor of Cyclin-dependent kinases (CDK) and is transcriptionally activated by p53
  • P21 is important in the response of cells to genotoxic stress and a major transcriptional target of p53 protein
  • The occurrence of p21 in the nucleus executes binding and inhibition activity of cyclin dependent kinases Cdk1 and Cdk2, and blocks the transition from G1 phase into S phase or from G2 phase into mitosis after DNA damage, which enables the repair of damaged DNA
  • In the cytoplasm, p21 protein has an anti-apoptotic effect
  • P21 is able to bind to and inhibit caspase 3, as well as the apoptotic kinases ASK1 and JNK
  • P21 exhibits a dual function in carcinogenesis, and acts as a tumor suppressor, prevents apoptosis, and acts as an oncogene.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PA130399

--


Antigen:
p21

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDKN1A

Gene Alias:
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1026, 114851, 12575

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.1% sodium azide

Gene Accession No.:
P38936, P39689

Gene Symbols:
CDKN1A

Immunogen:
Synthetic peptide (Human) (C terminal).

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA130411

--


Antigen:
Bcl-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12043, 24224, 596

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.1% sodium azide

Gene Accession No.:
P10415, P10417, P49950

Gene Symbols:
Bcl2

Immunogen:
Synthetic peptide (Human) (N terminal).

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA130493

--


Antigen:
ENO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ENO1

Gene Alias:
0610008I15; 2-phospho-D-glycerate hydrolase; 2-phospho-D-glycerate hydro-lyase; AL022784; alpha enolase; alpha enolase like 1; alpha-enolase; alpha-enolase; c-myc promoter-binding protein-1; c-Myc promoter binding protein; C-myc promoter-binding protein; Eno1; Eno-1; ENO1L1; enoa; Enolase 1; enolase 1, (alpha); enolase 1, alpha non-neuron; enolase-alpha; epididymis secretory protein Li 17; HEL-S-17; MBP-1; MBPB1; MPB1; MPB-1; MYC promoter-binding protein 1; NNE; Non-neural enolase; phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2023

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P06733

Gene Symbols:
ENO1

Immunogen:
Full-length human non-neuronal Enolase.

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA130595

--


Antigen:
Biotin

Classification:
Polyclonal

Conjugate:
HRP

Gene:
__

Gene Alias:
Vitamin B4

Host Species:
Goat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
50mM HEPES with proprietary stabilizer and 0.002% thimerosal

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Goats were immunized with biotinylated protein carrier in Freunds adjuvant.

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG