PA130411

Bcl-2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA130411-Each-of-1 In Stock ₹ 55,357.32

PA130411 - Each of 1

₹ 55,357.32

In Stock

Quantity

1

Base Price: ₹ 55,357.32

GST (18%): ₹ 9,964.318

Total Price: ₹ 65,321.638

Antigen

Bcl-2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Bcl2

Gene Alias

apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12043, 24224, 596

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 0.2% gelatin and 0.1% sodium azide

Gene Accession No.

P10415, P10417, P49950

Gene Symbols

Bcl2

Immunogen

Synthetic peptide (Human) (N terminal).

Quantity

1 mL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Suggested positive controls for this product are HL-60 and Jurkat
  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Compare Similar Items

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Thermo Scientific

PA130411

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Antigen:
Bcl-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12043, 24224, 596

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.1% sodium azide

Gene Accession No.:
P10415, P10417, P49950

Gene Symbols:
Bcl2

Immunogen:
Synthetic peptide (Human) (N terminal).

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PA130493

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Antigen:
ENO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ENO1

Gene Alias:
0610008I15; 2-phospho-D-glycerate hydrolase; 2-phospho-D-glycerate hydro-lyase; AL022784; alpha enolase; alpha enolase like 1; alpha-enolase; alpha-enolase; c-myc promoter-binding protein-1; c-Myc promoter binding protein; C-myc promoter-binding protein; Eno1; Eno-1; ENO1L1; enoa; Enolase 1; enolase 1, (alpha); enolase 1, alpha non-neuron; enolase-alpha; epididymis secretory protein Li 17; HEL-S-17; MBP-1; MBPB1; MPB1; MPB-1; MYC promoter-binding protein 1; NNE; Non-neural enolase; phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2023

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P06733

Gene Symbols:
ENO1

Immunogen:
Full-length human non-neuronal Enolase.

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA130595

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Antigen:
Biotin

Classification:
Polyclonal

Conjugate:
HRP

Gene:
__

Gene Alias:
Vitamin B4

Host Species:
Goat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
50mM HEPES with proprietary stabilizer and 0.002% thimerosal

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Goats were immunized with biotinylated protein carrier in Freunds adjuvant.

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA130601

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Antigen:
Complement C3a

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3r1; Complement C3; complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3 alpha-chain; complement component C3a; complement component C3b; CPAMD1; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; Plp; prepro-C3

Host Species:
Chicken

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12266

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P01027

Gene Symbols:
C3

Immunogen:
Mouse C3 alpha peptide aa 678-692

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgY