PA132503

CXCR3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA132503-Each-of-1 In Stock ₹ 50,908.20

PA132503 - Each of 1

₹ 50,908.20

In Stock

Quantity

1

Base Price: ₹ 50,908.20

GST (18%): ₹ 9,163.476

Total Price: ₹ 60,071.676

Antigen

CXCR3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CXCR3

Gene Alias

an; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; CKR-L2; Cmkar3; CXC; C-X-C chemokine receptor type 3; CXC motif chemokine; C-X-C motif chemokine receptor 3; Cxcr3; CXC-R3; CXCR-3; G protein-coupled receptor 9; GPR9; Interferon-inducible protein 10 receptor; IP10; IP10 receptor; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2833

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P49682

Gene Symbols

CXCR3

Immunogen

Synthetic 17 amino acid peptide from C-terminus of human CXCR3

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PA121627

--

Img

Thermo Scientific

PA128839

--

Img

Thermo Scientific

MA124668

--

Img

Thermo Scientific

PA121615

--

Img

Thermo Scientific

PA131217

--

Img

Thermo Scientific

OPA115292

--

Img

Thermo Scientific

PA122486

--

Img

Thermo Scientific

OPA115619

--

Description

  • PA1-32503 detects CXCR3 from human samples
  • This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed IP10 (interferon-g-inducible 10 kDa protein), Mig (monokine induced by interferon-g) and I-TAC (interferon-inducible T cell a-chemoattractant)
  • IP10, Mig and I-TAC belong to the structural subfamily of CXC chemokines, in which a single amino acid residue separates the first two of four highly conserved Cys residues
  • Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration
  • Inhibition by Bordetella pertussis toxin suggests that heterotrimeric G protein of the Gi-subclass couple to this protein
  • Signal transduction has not been further analyzed but may include the same enzymes that were identified in the signaling cascade induced by other chemokine receptors
  • As a consequence of chemokine-induced cellular desensitization (phosphorylation-dependent receptor internalization), cellular responses are typically rapid and short in duration
  • Cellular responsiveness is restored after dephosphorylation of intracellular receptors and subsequent recycling to the cell surface
  • This gene is prominently expressed in in vitro cultured effector/memory T cells, and in T cells present in many types of inflamed tissues
  • In addition, IP10, Mig and I-TAC are commonly produced by local cells in inflammatory lesion, suggesting that this gene and its chemokines participate in the recruitment of inflammatory cells
  • Therefore, this protein is a target for the development of small molecular weight antagonists, which may be used in the treatment of diverse inflammatory diseases
  • Multiple transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PA132503

--


Antigen:
CXCR3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CXCR3

Gene Alias:
an; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; CKR-L2; Cmkar3; CXC; C-X-C chemokine receptor type 3; CXC motif chemokine; C-X-C motif chemokine receptor 3; Cxcr3; CXC-R3; CXCR-3; G protein-coupled receptor 9; GPR9; Interferon-inducible protein 10 receptor; IP10; IP10 receptor; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2833

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P49682

Gene Symbols:
CXCR3

Immunogen:
Synthetic 17 amino acid peptide from C-terminus of human CXCR3

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA132780

--


Antigen:
FZD6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FZD6

Gene Alias:
frizzled 6; frizzled 6, seven transmembrane spanning receptor; frizzled class receptor 6; frizzled family receptor 6; frizzled homolog 6; frizzled homolog 6 (Drosophila); Frizzled6; frizzled-6; FZ6; Fz-6; Fzd6; FZD-6; HFZ6; mFz6; NDNC10; seven transmembrane helix receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8323

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
O60353

Gene Symbols:
FZD6

Immunogen:
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human Frizzled 6

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA1330

--


Antigen:
LXR alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NR1H3

Gene Alias:
AU018371; liver X nuclear receptor alpha variant 1; liver X receptor alpha; LXR; LXR alpha; Lxra; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10062

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q13133

Gene Symbols:
NR1H3

Immunogen:
Synthetic peptide corresponding to residues C D(318) F S Y N R E D F A K A(329) of human LXR alpha.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA133133

--


Antigen:
T7 Tag

Classification:
Polyclonal

Conjugate:
HRP

Gene:
__

Gene Alias:
MASMTGGQQMG; T7 cleavage

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
50mM HEPES with 0.002% thimerosal; pH 7.0

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
T7 epitope tag conjugated to KLH.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Tag

Product Type:
Antibody

Isotype:
IgG