PA14123

Cyclin E Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA14123-Each-of-1 In Stock ₹ 44,705.10

PA14123 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Cyclin E

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CCNE1

Gene Alias

AW538188; Ccne; Ccne1; CycE1; CYCLE; cyclin E; cyclin E1; cyclin Es; cyclin Et; E-S; G1/S-specific cyclin-E1; pCCNE1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

898

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P24864

Gene Symbols

CCNE1

Immunogen

Synthetic peptide corresponding to residues G(43) S Q P W D N N A V C(52) of Cyclin E1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-4123 detects Cyclin E1 in human samples
  • PA1-4123 has been successfully used in Western blot procedure
  • By Western blot this antibody detects a ∽40 kDa protein representing Cyclin E1 in transfected 293T cells
  • The PA1-4123 immunogen is a synthetic peptide corresponding to residues G(43) S Q P W D N N A V C(52) of Cyclin E1
  • Cyclin E belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle
  • Cyclins function as regulators of CDK kinases
  • Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event
  • Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition
  • This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase
  • Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis
  • This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB
  • Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described
  • Two additional splice variants were reported but detailed nucleotide sequence information is not yet available.

Compare Similar Items

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Thermo Scientific

PA14123

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Antigen:
Cyclin E

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCNE1

Gene Alias:
AW538188; Ccne; Ccne1; CycE1; CYCLE; cyclin E; cyclin E1; cyclin Es; cyclin Et; E-S; G1/S-specific cyclin-E1; pCCNE1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
898

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P24864

Gene Symbols:
CCNE1

Immunogen:
Synthetic peptide corresponding to residues G(43) S Q P W D N N A V C(52) of Cyclin E1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PA14129

--


Antigen:
Bcl-10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCL10

Gene Alias:
AI132454; B cell CLL/lymphoma 10; B cell leukemia/lymphoma 10; B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; B-cell lymphoma/leukemia 10; BCL10; Bcl-10; BCL10 immune signaling adaptor; C81403; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CARD-like apoptotic protein; CARMEN; caspase-recruiting domain-containing protein; cCARMEN; cE10; c-E10; CED-3/ICH-1 prodomain homologous E10-like regulator; cellular homolog of vCARMEN; Cellular-E10; CIPER; Clap; hCLAP; IMD37; Mamm; mammalian CARD-containing adapter molecule E10; mCIPER; mCLAP; mE10; OTTHUMP00000011647; OTTHUMP00000036080; RCD; RP11-234D19.2; R-RCD1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8915

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O95999

Gene Symbols:
BCL10

Immunogen:
Synthetic peptide corresponding to residues E(220) M F L P L R S R T V S R Q(233) C of Bcl10.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA14130

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Antigen:
CUG-BP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CELF2

Gene Alias:
B230218O03; B230345P09Rik; BRUNOL3; Bruno-like protein 3; C88023; cb906; CELF 2; Celf2; CELF-2; CUG triplet repeat RNA-binding protein 2; CUG triplet repeat, RNA binding protein 2; CUG-BP- and ETR-3-like factor 2; Cugbp- and Etr3-like factor 2; CUGBP Elav-like family member 2; CUGBP, Elav-like family member 2; Cugbp2; CUG-BP2; cugbp2 protein; D230046B21Rik; elav-type ribonucleoprotein-3; elav-type RNA-binding protein 3; ETR3; ETR-3; fj87b07; hNAPOR; mETR-3; mNapor; NAPOR; napor protein isoform; napor protein long isoform; napor protein short isoform; Napor-2; neur; neuroblastoma apoptosis-related RNA-binding protein; RNA-binding protein; RNA-binding protein Brunol3; RNA-binding protein BRUNOL-3; rNapor; RP23-124P7.1; wu:fj87b07

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10659, 14007

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O95319, Q9Z0H4

Gene Symbols:
CELF2

Immunogen:
Synthetic peptide corresponding to the C-terminal residues V(478) Q L K R S K N D S K P Y C(490) of human ETR3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PA14132

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Antigen:
RAD17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rad17

Gene Alias:
CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5884

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O75943

Gene Symbols:
Rad17

Immunogen:
Synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG