PA146021
p14ARF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA146021-Each-of-1 | In Stock | ₹ 50,309.28 |
PA146021 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,309.28
GST (18%): ₹ 9,055.67
Total Price: ₹ 59,364.95
Antigen
p14ARF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDKN2A
Gene Alias
Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor sup
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1029
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
Western Blot
Concentration
2.5 mg/mL
Formulation
tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No.
P42771
Gene Symbols
CDKN2A
Immunogen
A synthetic peptide made to a region within residues 100-173 of the human CDKN2A protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- By Western blot, PA1-46021 is specific for the ∽16 kDa CDKN2A protein (CDKN2A tends to run slightly higher than the theoretical MW of 14 kDa)
- Additional non-specific bands may be seen at ∽25 and 47 kDa
- Suggested positive control: BT549 cells or HeLa whole cell extract, antigen standard for CDKN2A (transient overexpression lysate)
- The INK4a locus on chromosome 9p21 is frequently affected in human tumors
- It encodes two structurally distinct tumor suppressor proteins, p16INK4a and the alternative reading frame protein, ARF (p14ARF in human and P19ARF in mouse)
- These two proteins interact with the upstream proteins: retinoblastoma protein and p53 tumor suppressors, respectively
- Each of these proteins has a role in the senescence of primary cells, activates pathways for cell cycle control and tumor suppression
- The p14ARF (or P19ARF in mouse) proteins can induce both G1 and G2 phase arrest in a manner that depends on functional p53
- The mouse and human ARF proteins have different functions in tumor suppression; this distinction may contribute to the different levels of tumor proneness of these species.
Compare Similar Items
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Antigen: p14ARF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDKN2A
Gene Alias: Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor sup
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1029
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: Western Blot
Concentration: 2.5 mg/mL
Formulation: tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No.: P42771
Gene Symbols: CDKN2A
Immunogen: A synthetic peptide made to a region within residues 100-173 of the human CDKN2A protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
p14ARF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDKN2A
Gene Alias:
Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor sup
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1029
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
Western Blot
Concentration:
2.5 mg/mL
Formulation:
tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No.:
P42771
Gene Symbols:
CDKN2A
Immunogen:
A synthetic peptide made to a region within residues 100-173 of the human CDKN2A protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PTGDS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTGDS
Gene Alias: 21kDa; Beta-trace protein; cerebrin-28; Glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin D synthase; lipocalin-type prostaglandin-D synthase; LPGDS; L-PGDS; PDS; PGD2; PGD2 synthase; PGDS; PGDS2; PH2DISO; Prostaglandin D synthase; prostaglandin D2 synthase; prostaglandin D2 synthase (21 kDa, brain); prostaglandin D2 synthase (brain); prostaglandin D2 synthase 21kDa (brain); prostaglandin-D2 synthase; Prostaglandin-H2 D-isomerase; Ptgds; Ptgs3; testis tissue sperm-binding protein Li 63n
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100067921, 19215, 25526, 286858, 397456, 493852, 5730
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 30% glycerol and 0.1% sodium azide
Gene Accession No.: O02853, O09114, O97921, P22057, P41222, Q29095, Q29487
Gene Symbols: PTGDS
Immunogen: A synthetic peptide made to a region within residues 25-100 of the human PTGDS protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Equine, Feline, Fish, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PTGDS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTGDS
Gene Alias:
21kDa; Beta-trace protein; cerebrin-28; Glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin D synthase; lipocalin-type prostaglandin-D synthase; LPGDS; L-PGDS; PDS; PGD2; PGD2 synthase; PGDS; PGDS2; PH2DISO; Prostaglandin D synthase; prostaglandin D2 synthase; prostaglandin D2 synthase (21 kDa, brain); prostaglandin D2 synthase (brain); prostaglandin D2 synthase 21kDa (brain); prostaglandin-D2 synthase; Prostaglandin-H2 D-isomerase; Ptgds; Ptgs3; testis tissue sperm-binding protein Li 63n
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100067921, 19215, 25526, 286858, 397456, 493852, 5730
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 30% glycerol and 0.1% sodium azide
Gene Accession No.:
O02853, O09114, O97921, P22057, P41222, Q29095, Q29487
Gene Symbols:
PTGDS
Immunogen:
A synthetic peptide made to a region within residues 25-100 of the human PTGDS protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Equine, Feline, Fish, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Synapsin 1 (Ser9)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SYN1
Gene Alias: Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20964, 24949, 570672
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: O88935, P09951
Gene Symbols: SYN1
Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser9 of rat SYN1 conjugated to KLH
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat, Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Synapsin 1 (Ser9)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SYN1
Gene Alias:
Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20964, 24949, 570672
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
__
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
O88935, P09951
Gene Symbols:
SYN1
Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser9 of rat SYN1 conjugated to KLH
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat, Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Synapsin 1 (Ser603)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SYN1
Gene Alias: Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20964, 24949, 6853
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: O88935, P09951, P17600
Gene Symbols: SYN1
Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser603 of rat SYN1 conjugated to KLH
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Synapsin 1 (Ser603)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SYN1
Gene Alias:
Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20964, 24949, 6853
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
O88935, P09951, P17600
Gene Symbols:
SYN1
Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser603 of rat SYN1 conjugated to KLH
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG