PIMA532133
p16INK4a Recombinant Rabbit Monoclonal Antibody (SU0702), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532133-Each-of-1 | In Stock | ₹ 51,036.54 |
PIMA532133 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,036.54
GST (18%): ₹ 9,186.577
Total Price: ₹ 60,223.117
Antigen
p16INK4a
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P42771
Gene Symbols
CDKN2A
Immunogen
Synthetic peptide within Human p16INK4A aa 107-156
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SU0702
Conjugate
Unconjugated
Gene
CDKN2A
Gene Alias
Alternative reading frame, Arf, ARF-INK4a, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, Cdkn2a, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, Cyclin dependent kinase 4 inhibitor A, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, HGNC:1787, inhibits CDK4, INK4, INK4A, Ink4a/Arf, INK4a-ARF, isoforms 1/2/3, Melanoma p16 inhibits CDK4, mitochondrial smARF, MLM, MTS1, MTS-1, Multiple tumor suppressor 1, P14, P14 P16, P14ARF, p16, p16(INK4a), p16Cdkn2a, P16INK4, p16-INK4, p16INK4a, p16-INK4a, P19, P19 TP16, p19<ARF>, P19ARF, Pctr1, RGD:2323}, TP16, Tumor suppressor ARF
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1029
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This gene generates several transcript variants which differ in their first exons
- At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase
- The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants
- This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53
- In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control
- This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.
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Antigen: p16INK4a
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P42771
Gene Symbols: CDKN2A
Immunogen: Synthetic peptide within Human p16INK4A aa 107-156
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SU0702
Conjugate: Unconjugated
Gene: CDKN2A
Gene Alias: Alternative reading frame, Arf, ARF-INK4a, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, Cdkn2a, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, Cyclin dependent kinase 4 inhibitor A, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, HGNC:1787, inhibits CDK4, INK4, INK4A, Ink4a/Arf, INK4a-ARF, isoforms 1/2/3, Melanoma p16 inhibits CDK4, mitochondrial smARF, MLM, MTS1, MTS-1, Multiple tumor suppressor 1, P14, P14 P16, P14ARF, p16, p16(INK4a), p16Cdkn2a, P16INK4, p16-INK4, p16INK4a, p16-INK4a, P19, P19 TP16, p19<ARF>, P19ARF, Pctr1, RGD:2323}, TP16, Tumor suppressor ARF
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1029
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
p16INK4a
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P42771
Gene Symbols:
CDKN2A
Immunogen:
Synthetic peptide within Human p16INK4A aa 107-156
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SU0702
Conjugate:
Unconjugated
Gene:
CDKN2A
Gene Alias:
Alternative reading frame, Arf, ARF-INK4a, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, Cdkn2a, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, Cyclin dependent kinase 4 inhibitor A, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, HGNC:1787, inhibits CDK4, INK4, INK4A, Ink4a/Arf, INK4a-ARF, isoforms 1/2/3, Melanoma p16 inhibits CDK4, mitochondrial smARF, MLM, MTS1, MTS-1, Multiple tumor suppressor 1, P14, P14 P16, P14ARF, p16, p16(INK4a), p16Cdkn2a, P16INK4, p16-INK4, p16INK4a, p16-INK4a, P19, P19 TP16, p19<ARF>, P19ARF, Pctr1, RGD:2323}, TP16, Tumor suppressor ARF
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1029
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MYLK
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q15746, Q6PDN3
Gene Symbols: MYLK
Immunogen: Synthetic peptide within Human MYLK aa 1,865-1,914
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SU40-06
Conjugate: Unconjugated
Gene: MYLK
Gene Alias: 155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 107589, 288057, 4638
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MYLK
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q15746, Q6PDN3
Gene Symbols:
MYLK
Immunogen:
Synthetic peptide within Human MYLK aa 1,865-1,914
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SU40-06
Conjugate:
Unconjugated
Gene:
MYLK
Gene Alias:
155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
107589, 288057, 4638
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Caspase 1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P29452, P29466, P43527
Gene Symbols: CASP1
Immunogen: Recombinant protein within Human Caspase-1 aa 213-404
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Western Blot, Western Blot
Clone: SU40-07
Conjugate: Unconjugated
Gene: CASP1
Gene Alias: CASP1, CASP-1, CASP1 nirs variant 1, caspase 1, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), Caspase1, caspase-1, Caspase-1 subunit p10, Caspase-1 subunit p20, ICE, IL-1 beta-converting enzyme, IL-1B converting enzyme, IL1BC, IL-1BC, IL1BCE, IL1B-convertase, interleukin 1 beta-converting enzyme, interleukin 1, beta, convertase, interleukin 1-B converting enzyme, Interleukin 1beta converting enzyme, interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12362, 25166, 834
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Caspase 1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P29452, P29466, P43527
Gene Symbols:
CASP1
Immunogen:
Recombinant protein within Human Caspase-1 aa 213-404
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Western Blot, Western Blot
Clone:
SU40-07
Conjugate:
Unconjugated
Gene:
CASP1
Gene Alias:
CASP1, CASP-1, CASP1 nirs variant 1, caspase 1, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), Caspase1, caspase-1, Caspase-1 subunit p10, Caspase-1 subunit p20, ICE, IL-1 beta-converting enzyme, IL-1B converting enzyme, IL1BC, IL-1BC, IL1BCE, IL1B-convertase, interleukin 1 beta-converting enzyme, interleukin 1, beta, convertase, interleukin 1-B converting enzyme, Interleukin 1beta converting enzyme, interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12362, 25166, 834
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: H3K56ac
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P68431, P68433, P84228, Q71DI3
Gene Symbols: H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7
Immunogen: Synthetic peptide within Human Histone H3 aa 31-80
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SU30-10
Conjugate: Unconjugated
Gene: H3C15
Gene Alias: Acetyl H3, Acetyl Histone H3, Acetyl-H3 K56, Acetyl-H3 Lys56, Acetyl-Histone H3 K56, Acetyl-Histone H3 Lys56, H3, H3 histone, H3 histone family, member A, H3 histone family, member I, H3 histone family, member K, H3 histone family, member L, H3 histone family, member M, H3 histone, family 2, H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B), H3 histone, family 3C, H3 K56ac, H3.1-221, H3.1-291, H3.1-I, H3.2, H3.2-221, H3.2-614, H3.2-615, H3.2-616, H3.3A, H3.3B, H3.5, H3/A, H3/b, H3/d, H3/f, H3/i, H3/j, H3/k, H3/l, H3/M, H3/n, H3/o, H3-143, H3-291, H3-3A, H3-3b, H3-53, H3-614, H3a, H3b, H3-B, H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3f, H3-F, H3F1K, H3F2, H3F3, H3F3A, H3f3b, H3F3C, H3FA, H3FB, H3FC HIST1H3C, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, H3FM, H3FN, H3g, H3h, H3i, H3K56, H3Lys56ac, Hist1, HIST1H3A, HIST1H3B, Hist1h3c, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, HIST2H3A, Hist2h3b, HIST2H3C, Hist2h3c1, Hist2h3c2, Hist2h3c2-ps, Hist2h3ca1, Hist2h3ca2, HIST2H3D, histone 1, H3a, histone 1, H3b, histone 1, H3f, histone 1, H3h, histone 2, H3a, histone 2, H3c, histone 2, H3c2, histone 2, H3ca2, Histone 3, histone cluster 1, H3a, histone cluster 1, H3b, histone cluster 1, H3f, histone cluster 1, H3h, histone cluster 2, H3a, histone cluster 2, H3c, histone cluster 2, H3c2, histone cluster 2, H3c2, pseudogene, histone gene complex 1, histone H3, histone H3.1, Histone H3.2, histone H3.3, Histone H3.3C, histone H3.5, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, histone H3/l, Histone H3/m, histone H3/o, Histone H3K56, histone variant H3.5, M32461, PP781
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 126961, 260423, 319150, 319152, 333932, 360198, 8350, 8356, 8357, 8358, 8968, 97114
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
H3K56ac
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P68431, P68433, P84228, Q71DI3
Gene Symbols:
H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7
Immunogen:
Synthetic peptide within Human Histone H3 aa 31-80
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SU30-10
Conjugate:
Unconjugated
Gene:
H3C15
Gene Alias:
Acetyl H3, Acetyl Histone H3, Acetyl-H3 K56, Acetyl-H3 Lys56, Acetyl-Histone H3 K56, Acetyl-Histone H3 Lys56, H3, H3 histone, H3 histone family, member A, H3 histone family, member I, H3 histone family, member K, H3 histone family, member L, H3 histone family, member M, H3 histone, family 2, H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B), H3 histone, family 3C, H3 K56ac, H3.1-221, H3.1-291, H3.1-I, H3.2, H3.2-221, H3.2-614, H3.2-615, H3.2-616, H3.3A, H3.3B, H3.5, H3/A, H3/b, H3/d, H3/f, H3/i, H3/j, H3/k, H3/l, H3/M, H3/n, H3/o, H3-143, H3-291, H3-3A, H3-3b, H3-53, H3-614, H3a, H3b, H3-B, H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3f, H3-F, H3F1K, H3F2, H3F3, H3F3A, H3f3b, H3F3C, H3FA, H3FB, H3FC HIST1H3C, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, H3FM, H3FN, H3g, H3h, H3i, H3K56, H3Lys56ac, Hist1, HIST1H3A, HIST1H3B, Hist1h3c, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, HIST2H3A, Hist2h3b, HIST2H3C, Hist2h3c1, Hist2h3c2, Hist2h3c2-ps, Hist2h3ca1, Hist2h3ca2, HIST2H3D, histone 1, H3a, histone 1, H3b, histone 1, H3f, histone 1, H3h, histone 2, H3a, histone 2, H3c, histone 2, H3c2, histone 2, H3ca2, Histone 3, histone cluster 1, H3a, histone cluster 1, H3b, histone cluster 1, H3f, histone cluster 1, H3h, histone cluster 2, H3a, histone cluster 2, H3c, histone cluster 2, H3c2, histone cluster 2, H3c2, pseudogene, histone gene complex 1, histone H3, histone H3.1, Histone H3.2, histone H3.3, Histone H3.3C, histone H3.5, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, histone H3/l, Histone H3/m, histone H3/o, Histone H3K56, histone variant H3.5, M32461, PP781
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
126961, 260423, 319150, 319152, 333932, 360198, 8350, 8356, 8357, 8358, 8968, 97114
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid