PIMA532136

MYLK Recombinant Rabbit Monoclonal Antibody (SU40-06), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532136-Each-of-1 In Stock ₹ 45,646.26

PIMA532136 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

MYLK

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q15746, Q6PDN3

Gene Symbols

MYLK

Immunogen

Synthetic peptide within Human MYLK aa 1,865-1,914

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SU40-06

Conjugate

Unconjugated

Gene

MYLK

Gene Alias

155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

107589, 288057, 4638

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA532025

--

Img

Thermo Scientific

PIMA532835

--

Img

Thermo Scientific

PIMA532080

--

Img

Thermo Scientific

PIMA532237

--

Img

Thermo Scientific

PIMA532482

--

Img

Thermo Scientific

PIMA532167

--

Img

Thermo Scientific

PIMA532149

--

Img

Thermo Scientific

PIMA532180

--

Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • MYLK (MLCK) is a serine/threonine kinase that phosphorylates myosin regulatory light chains to assist in the production of contractile activity (myosin-actin interaction)
  • MLCK is responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments
  • It is a central determinant in the development of vascular permeability and tissue edema formation
  • In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells
  • MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis
  • Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific
  • Non-muscle isoform 2 is the dominant splice variant expressed in various tissues
  • The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues
  • MLCK is probably down-regulated by phosphorylation
  • The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532136

--


Antigen:
MYLK

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q15746, Q6PDN3

Gene Symbols:
MYLK

Immunogen:
Synthetic peptide within Human MYLK aa 1,865-1,914

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SU40-06

Conjugate:
Unconjugated

Gene:
MYLK

Gene Alias:
155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
107589, 288057, 4638

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532137

--


Antigen:
Caspase 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P29452, P29466, P43527

Gene Symbols:
CASP1

Immunogen:
Recombinant protein within Human Caspase-1 aa 213-404

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot, Western Blot

Clone:
SU40-07

Conjugate:
Unconjugated

Gene:
CASP1

Gene Alias:
CASP1, CASP-1, CASP1 nirs variant 1, caspase 1, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), Caspase1, caspase-1, Caspase-1 subunit p10, Caspase-1 subunit p20, ICE, IL-1 beta-converting enzyme, IL-1B converting enzyme, IL1BC, IL-1BC, IL1BCE, IL1B-convertase, interleukin 1 beta-converting enzyme, interleukin 1, beta, convertase, interleukin 1-B converting enzyme, Interleukin 1beta converting enzyme, interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12362, 25166, 834

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532138

--


Antigen:
H3K56ac

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P68431, P68433, P84228, Q71DI3

Gene Symbols:
H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7

Immunogen:
Synthetic peptide within Human Histone H3 aa 31-80

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SU30-10

Conjugate:
Unconjugated

Gene:
H3C15

Gene Alias:
Acetyl H3, Acetyl Histone H3, Acetyl-H3 K56, Acetyl-H3 Lys56, Acetyl-Histone H3 K56, Acetyl-Histone H3 Lys56, H3, H3 histone, H3 histone family, member A, H3 histone family, member I, H3 histone family, member K, H3 histone family, member L, H3 histone family, member M, H3 histone, family 2, H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B), H3 histone, family 3C, H3 K56ac, H3.1-221, H3.1-291, H3.1-I, H3.2, H3.2-221, H3.2-614, H3.2-615, H3.2-616, H3.3A, H3.3B, H3.5, H3/A, H3/b, H3/d, H3/f, H3/i, H3/j, H3/k, H3/l, H3/M, H3/n, H3/o, H3-143, H3-291, H3-3A, H3-3b, H3-53, H3-614, H3a, H3b, H3-B, H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3f, H3-F, H3F1K, H3F2, H3F3, H3F3A, H3f3b, H3F3C, H3FA, H3FB, H3FC HIST1H3C, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, H3FM, H3FN, H3g, H3h, H3i, H3K56, H3Lys56ac, Hist1, HIST1H3A, HIST1H3B, Hist1h3c, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, HIST2H3A, Hist2h3b, HIST2H3C, Hist2h3c1, Hist2h3c2, Hist2h3c2-ps, Hist2h3ca1, Hist2h3ca2, HIST2H3D, histone 1, H3a, histone 1, H3b, histone 1, H3f, histone 1, H3h, histone 2, H3a, histone 2, H3c, histone 2, H3c2, histone 2, H3ca2, Histone 3, histone cluster 1, H3a, histone cluster 1, H3b, histone cluster 1, H3f, histone cluster 1, H3h, histone cluster 2, H3a, histone cluster 2, H3c, histone cluster 2, H3c2, histone cluster 2, H3c2, pseudogene, histone gene complex 1, histone H3, histone H3.1, Histone H3.2, histone H3.3, Histone H3.3C, histone H3.5, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, histone H3/l, Histone H3/m, histone H3/o, Histone H3K56, histone variant H3.5, M32461, PP781

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
126961, 260423, 319150, 319152, 333932, 360198, 8350, 8356, 8357, 8358, 8968, 97114

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532139

--


Antigen:
M-CSF

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P09603

Gene Symbols:
Csf1

Immunogen:
Synthetic peptide within Human MCSF aa 56-105

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
SU0413

Conjugate:
Unconjugated

Gene:
Csf1

Gene Alias:
C87615, colony stimulating factor 1, colony stimulating factor 1 (macrophage), colony-stimulating factor-1 splice variant, CSF1, CSF-1, Csfm, H-MCSF, lanimostim, macrophage colony stimulating factor 1, macrophage colony stimulating factor alpha, macrophage colony stimulating factor beta, macrophage colony-stimulating factor, macrophage colony-stimulating factor 1, macrophage colony-stimulating factor beta, macrophage-colony stimulating factor alpha, MCSF, MCSF alpha, MCSFBETA, MGC31930, M-MCSF, op, osteopetrosis, Processed macrophage colony-stimulating factor 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1435

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid