PIMA532180
Chk1 Recombinant Rabbit Monoclonal Antibody (ST57-09), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532180-Each-of-1 | In Stock | ₹ 51,036.54 |
PIMA532180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,036.54
GST (18%): ₹ 9,186.577
Total Price: ₹ 60,223.117
Antigen
Chk1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O14757
Gene Symbols
Chek1
Immunogen
Synthetic peptide within Human Chk1 aa 431-476
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
ST57-09
Conjugate
Unconjugated
Gene
Chek1
Gene Alias
C85740, Cell cycle checkpoint kinase, checkpoint kinase 1, checkpoint kinase 1 homolog, checkpoint kinase-1, Checkpoint, S. pombe, homolog of, 1, CHEK1, CHK1, CHK1 checkpoint homolog, Chk1-S, homolog of Chk1-S, HRD1 Protein, rad27, rad27 homolog, serine/threonine protein kinase CHK1, serine/threonine-protein kinase Chk1, Synoviolin, YBR1742, YBR274W
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1111
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised
- CHK1 is a key mediator in the DNA damage-induced checkpoint network
- CHK1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress
- When the G2 or S checkpoint is abrogated by the inhibition of CHK1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase
- Thus, CHK1 inhibitors can preferentially potentiate the efficacy of DNA damaging agents in cancer cells, and Chk1 is an attractive therapeutic target for cancer treatment, especially since approximately 50% of all human cancers are p53-deficient.
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Antigen: Chk1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O14757
Gene Symbols: Chek1
Immunogen: Synthetic peptide within Human Chk1 aa 431-476
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: ST57-09
Conjugate: Unconjugated
Gene: Chek1
Gene Alias: C85740, Cell cycle checkpoint kinase, checkpoint kinase 1, checkpoint kinase 1 homolog, checkpoint kinase-1, Checkpoint, S. pombe, homolog of, 1, CHEK1, CHK1, CHK1 checkpoint homolog, Chk1-S, homolog of Chk1-S, HRD1 Protein, rad27, rad27 homolog, serine/threonine protein kinase CHK1, serine/threonine-protein kinase Chk1, Synoviolin, YBR1742, YBR274W
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1111
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Chk1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O14757
Gene Symbols:
Chek1
Immunogen:
Synthetic peptide within Human Chk1 aa 431-476
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
ST57-09
Conjugate:
Unconjugated
Gene:
Chek1
Gene Alias:
C85740, Cell cycle checkpoint kinase, checkpoint kinase 1, checkpoint kinase 1 homolog, checkpoint kinase-1, Checkpoint, S. pombe, homolog of, 1, CHEK1, CHK1, CHK1 checkpoint homolog, Chk1-S, homolog of Chk1-S, HRD1 Protein, rad27, rad27 homolog, serine/threonine protein kinase CHK1, serine/threonine-protein kinase Chk1, Synoviolin, YBR1742, YBR274W
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1111
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: GRK2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P25098, P26817, Q99MK8
Gene Symbols: GRK2
Immunogen: Synthetic peptide within Human GRK2 aa 640-689
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry, Western Blot
Clone: ST05-60
Conjugate: Unconjugated
Gene: GRK2
Gene Alias: ADRBK1, Adrbk-1, adrenergic beta receptor kinase 1, adrenergic receptor kinase, beta 1, adrenergic, beta, receptor kinase 1, BARK, BARK1, Bark-1, beta ARK, Beta-adrenergic receptor kinase 1, beta-adrenergic receptor kinase 1 beta ARK1, beta-AR kinase-1, betaARK1, BETA-ARK1, beta-ARK-1, EC 2.7.1.126, G protein-coupled receptor kinase 2, G-protein coupled receptor kinase 2, G-protein-coupled receptor kinase 2, grk 2, Grk2, GRK-2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 110355, 156, 25238
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
GRK2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P25098, P26817, Q99MK8
Gene Symbols:
GRK2
Immunogen:
Synthetic peptide within Human GRK2 aa 640-689
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry, Western Blot
Clone:
ST05-60
Conjugate:
Unconjugated
Gene:
GRK2
Gene Alias:
ADRBK1, Adrbk-1, adrenergic beta receptor kinase 1, adrenergic receptor kinase, beta 1, adrenergic, beta, receptor kinase 1, BARK, BARK1, Bark-1, beta ARK, Beta-adrenergic receptor kinase 1, beta-adrenergic receptor kinase 1 beta ARK1, beta-AR kinase-1, betaARK1, BETA-ARK1, beta-ARK-1, EC 2.7.1.126, G protein-coupled receptor kinase 2, G-protein coupled receptor kinase 2, G-protein-coupled receptor kinase 2, grk 2, Grk2, GRK-2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
110355, 156, 25238
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Cytokeratin 10
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P02535, P13645, Q6IFW6
Gene Symbols: KRT10
Immunogen: Synthetic peptide within Human Cytokeratin 10 aa 541-584
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: ST05-43
Conjugate: Unconjugated
Gene: KRT10
Gene Alias: 56 kDa cytokeratin, BCIE, BIE, CK10, CK-10, CK-17, cytokeratin 10, cytokeratin-10, cytokeratin-17, D130054E02Rik, EHK, epidermal keratin 10, epithelial keratin 10, intermediate filament protein, K10, K1C1, Ka10, Ker10, keratin 10, keratin 10 (epidermolytic hyperkeratosis, keratosis palmaris et plantaris), keratin 10, type I, keratin complex 1, acidic, gene 10, keratin, type I cytoskeletal 10, Keratin, type I cytoskeletal 59 kDa, keratin-10, keratin-17, KPP, Krt-1.10, KRT10, krt10 {ECO:0000250, Krt1-10, suprabasal cytokeratin 10, type I keratin KA10, UniProtKB:P13645}
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 16661, 3858, 450225
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Cytokeratin 10
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P02535, P13645, Q6IFW6
Gene Symbols:
KRT10
Immunogen:
Synthetic peptide within Human Cytokeratin 10 aa 541-584
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
ST05-43
Conjugate:
Unconjugated
Gene:
KRT10
Gene Alias:
56 kDa cytokeratin, BCIE, BIE, CK10, CK-10, CK-17, cytokeratin 10, cytokeratin-10, cytokeratin-17, D130054E02Rik, EHK, epidermal keratin 10, epithelial keratin 10, intermediate filament protein, K10, K1C1, Ka10, Ker10, keratin 10, keratin 10 (epidermolytic hyperkeratosis, keratosis palmaris et plantaris), keratin 10, type I, keratin complex 1, acidic, gene 10, keratin, type I cytoskeletal 10, Keratin, type I cytoskeletal 59 kDa, keratin-10, keratin-17, KPP, Krt-1.10, KRT10, krt10 {ECO:0000250, Krt1-10, suprabasal cytokeratin 10, type I keratin KA10, UniProtKB:P13645}
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
16661, 3858, 450225
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Sodium Potassium ATPase
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P05023, P06685, Q13733, Q64541, Q8VDN2, Q9WV27
Gene Symbols: ATP1A1, ATP1A4
Immunogen: Synthetic peptide within Human ATP1A1 aa 39-83
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot
Clone: ST0533
Conjugate: Unconjugated
Gene: ATP1A4
Gene Alias: ATP1A1, ATP1A4, ATP1AL2, Atpa-1, ATPase Na+/K+ transporting subunit alpha 1, ATPase Na+/K+ transporting subunit alpha 4, ATPase, Na+/K+ transporting, alpha 1 polypeptide, ATPase, Na+/K+ transporting, alpha 4 polypeptide, ATPase, Na+/K+ transporting, alpha polypeptide-like 2, ATPase, Na+K+ transporting, alpha 1, BC010319, Na(+)/K(+) ATPase alpha-1 subunit, Na(+)/K(+) ATPase alpha-4 subunit, Na, K-ATPase, alpha-A catalytic polypeptide, Na,K-ATPase alpha-1 subunit, Na,K-ATPase catalytic subunit alpha-A protein, Na,K-ATPase subunit alpha-C, Na+/K+ ATPase 1, Na+/K+ ATPase 4, Na+/K+ ATPase alpha 4 subunit, Na+/K+ ATPase, alpha-D polypeptide, Nkaa1b, sodium pump 4, sodium pump subunit alpha-1, Sodium pump subunit alpha-4, sodium/potassium-transporting ATPase alpha-4 chain, sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-4, sodium-potassium ATPase catalytic subunit alpha-1, sodium-potassium ATPase catalytic subunit alpha-4, sodium-potassium-ATPase, alpha 1 polypeptide
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11928, 24211, 27222, 29132, 476, 480
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Sodium Potassium ATPase
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P05023, P06685, Q13733, Q64541, Q8VDN2, Q9WV27
Gene Symbols:
ATP1A1, ATP1A4
Immunogen:
Synthetic peptide within Human ATP1A1 aa 39-83
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot
Clone:
ST0533
Conjugate:
Unconjugated
Gene:
ATP1A4
Gene Alias:
ATP1A1, ATP1A4, ATP1AL2, Atpa-1, ATPase Na+/K+ transporting subunit alpha 1, ATPase Na+/K+ transporting subunit alpha 4, ATPase, Na+/K+ transporting, alpha 1 polypeptide, ATPase, Na+/K+ transporting, alpha 4 polypeptide, ATPase, Na+/K+ transporting, alpha polypeptide-like 2, ATPase, Na+K+ transporting, alpha 1, BC010319, Na(+)/K(+) ATPase alpha-1 subunit, Na(+)/K(+) ATPase alpha-4 subunit, Na, K-ATPase, alpha-A catalytic polypeptide, Na,K-ATPase alpha-1 subunit, Na,K-ATPase catalytic subunit alpha-A protein, Na,K-ATPase subunit alpha-C, Na+/K+ ATPase 1, Na+/K+ ATPase 4, Na+/K+ ATPase alpha 4 subunit, Na+/K+ ATPase, alpha-D polypeptide, Nkaa1b, sodium pump 4, sodium pump subunit alpha-1, Sodium pump subunit alpha-4, sodium/potassium-transporting ATPase alpha-4 chain, sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-4, sodium-potassium ATPase catalytic subunit alpha-1, sodium-potassium ATPase catalytic subunit alpha-4, sodium-potassium-ATPase, alpha 1 polypeptide
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11928, 24211, 27222, 29132, 476, 480
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid