PIMA532181
GRK2 Recombinant Rabbit Monoclonal Antibody (ST05-60), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532181-Each-of-1 | In Stock | ₹ 56,897.40 |
PIMA532181 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,897.40
GST (18%): ₹ 10,241.532
Total Price: ₹ 67,138.932
Antigen
GRK2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P25098, P26817, Q99MK8
Gene Symbols
GRK2
Immunogen
Synthetic peptide within Human GRK2 aa 640-689
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Clone
ST05-60
Conjugate
Unconjugated
Gene
GRK2
Gene Alias
ADRBK1, Adrbk-1, adrenergic beta receptor kinase 1, adrenergic receptor kinase, beta 1, adrenergic, beta, receptor kinase 1, BARK, BARK1, Bark-1, beta ARK, Beta-adrenergic receptor kinase 1, beta-adrenergic receptor kinase 1 beta ARK1, beta-AR kinase-1, betaARK1, BETA-ARK1, beta-ARK-1, EC 2.7.1.126, G protein-coupled receptor kinase 2, G-protein coupled receptor kinase 2, G-protein-coupled receptor kinase 2, grk 2, Grk2, GRK-2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
110355, 156, 25238
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- ADRBK1 (GRK2) is a serine/threonine kinase
- Many of the G protein-coupled receptors are known to be phosphorylated by G protein-dependent receptor kinases (GRKs)
- G protein-coupled receptor kinases (GRKs) are important regulators of G protein-coupled receptors(GPCRs)
- GRK2 (83 kDa), one of six members of this family that have been identified, is ubiquitously expressed in mammals
- After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs (e.g., a2-adrenergic receptor) are phosphorylated by GRKs
- Internalization of the GPCRs, regulated by beta-arrestin-1, leads to activation of the Ras - Raf - ERK1&2 signaling pathway
- GRK2 activity is tightly controlled by different mechanisms including phosphorylation by kinases such as PKC, Src and ERK1&2, as well as interaction with various proteins
- ERK phosphorylates and thus inactivates GRK2 on serine 670 in a negative feedback mechanism.
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Antigen: GRK2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P25098, P26817, Q99MK8
Gene Symbols: GRK2
Immunogen: Synthetic peptide within Human GRK2 aa 640-689
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry, Western Blot
Clone: ST05-60
Conjugate: Unconjugated
Gene: GRK2
Gene Alias: ADRBK1, Adrbk-1, adrenergic beta receptor kinase 1, adrenergic receptor kinase, beta 1, adrenergic, beta, receptor kinase 1, BARK, BARK1, Bark-1, beta ARK, Beta-adrenergic receptor kinase 1, beta-adrenergic receptor kinase 1 beta ARK1, beta-AR kinase-1, betaARK1, BETA-ARK1, beta-ARK-1, EC 2.7.1.126, G protein-coupled receptor kinase 2, G-protein coupled receptor kinase 2, G-protein-coupled receptor kinase 2, grk 2, Grk2, GRK-2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 110355, 156, 25238
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
GRK2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P25098, P26817, Q99MK8
Gene Symbols:
GRK2
Immunogen:
Synthetic peptide within Human GRK2 aa 640-689
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry, Western Blot
Clone:
ST05-60
Conjugate:
Unconjugated
Gene:
GRK2
Gene Alias:
ADRBK1, Adrbk-1, adrenergic beta receptor kinase 1, adrenergic receptor kinase, beta 1, adrenergic, beta, receptor kinase 1, BARK, BARK1, Bark-1, beta ARK, Beta-adrenergic receptor kinase 1, beta-adrenergic receptor kinase 1 beta ARK1, beta-AR kinase-1, betaARK1, BETA-ARK1, beta-ARK-1, EC 2.7.1.126, G protein-coupled receptor kinase 2, G-protein coupled receptor kinase 2, G-protein-coupled receptor kinase 2, grk 2, Grk2, GRK-2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
110355, 156, 25238
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Cytokeratin 10
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P02535, P13645, Q6IFW6
Gene Symbols: KRT10
Immunogen: Synthetic peptide within Human Cytokeratin 10 aa 541-584
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: ST05-43
Conjugate: Unconjugated
Gene: KRT10
Gene Alias: 56 kDa cytokeratin, BCIE, BIE, CK10, CK-10, CK-17, cytokeratin 10, cytokeratin-10, cytokeratin-17, D130054E02Rik, EHK, epidermal keratin 10, epithelial keratin 10, intermediate filament protein, K10, K1C1, Ka10, Ker10, keratin 10, keratin 10 (epidermolytic hyperkeratosis, keratosis palmaris et plantaris), keratin 10, type I, keratin complex 1, acidic, gene 10, keratin, type I cytoskeletal 10, Keratin, type I cytoskeletal 59 kDa, keratin-10, keratin-17, KPP, Krt-1.10, KRT10, krt10 {ECO:0000250, Krt1-10, suprabasal cytokeratin 10, type I keratin KA10, UniProtKB:P13645}
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 16661, 3858, 450225
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Cytokeratin 10
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P02535, P13645, Q6IFW6
Gene Symbols:
KRT10
Immunogen:
Synthetic peptide within Human Cytokeratin 10 aa 541-584
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
ST05-43
Conjugate:
Unconjugated
Gene:
KRT10
Gene Alias:
56 kDa cytokeratin, BCIE, BIE, CK10, CK-10, CK-17, cytokeratin 10, cytokeratin-10, cytokeratin-17, D130054E02Rik, EHK, epidermal keratin 10, epithelial keratin 10, intermediate filament protein, K10, K1C1, Ka10, Ker10, keratin 10, keratin 10 (epidermolytic hyperkeratosis, keratosis palmaris et plantaris), keratin 10, type I, keratin complex 1, acidic, gene 10, keratin, type I cytoskeletal 10, Keratin, type I cytoskeletal 59 kDa, keratin-10, keratin-17, KPP, Krt-1.10, KRT10, krt10 {ECO:0000250, Krt1-10, suprabasal cytokeratin 10, type I keratin KA10, UniProtKB:P13645}
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
16661, 3858, 450225
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Sodium Potassium ATPase
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P05023, P06685, Q13733, Q64541, Q8VDN2, Q9WV27
Gene Symbols: ATP1A1, ATP1A4
Immunogen: Synthetic peptide within Human ATP1A1 aa 39-83
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot
Clone: ST0533
Conjugate: Unconjugated
Gene: ATP1A4
Gene Alias: ATP1A1, ATP1A4, ATP1AL2, Atpa-1, ATPase Na+/K+ transporting subunit alpha 1, ATPase Na+/K+ transporting subunit alpha 4, ATPase, Na+/K+ transporting, alpha 1 polypeptide, ATPase, Na+/K+ transporting, alpha 4 polypeptide, ATPase, Na+/K+ transporting, alpha polypeptide-like 2, ATPase, Na+K+ transporting, alpha 1, BC010319, Na(+)/K(+) ATPase alpha-1 subunit, Na(+)/K(+) ATPase alpha-4 subunit, Na, K-ATPase, alpha-A catalytic polypeptide, Na,K-ATPase alpha-1 subunit, Na,K-ATPase catalytic subunit alpha-A protein, Na,K-ATPase subunit alpha-C, Na+/K+ ATPase 1, Na+/K+ ATPase 4, Na+/K+ ATPase alpha 4 subunit, Na+/K+ ATPase, alpha-D polypeptide, Nkaa1b, sodium pump 4, sodium pump subunit alpha-1, Sodium pump subunit alpha-4, sodium/potassium-transporting ATPase alpha-4 chain, sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-4, sodium-potassium ATPase catalytic subunit alpha-1, sodium-potassium ATPase catalytic subunit alpha-4, sodium-potassium-ATPase, alpha 1 polypeptide
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11928, 24211, 27222, 29132, 476, 480
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Sodium Potassium ATPase
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P05023, P06685, Q13733, Q64541, Q8VDN2, Q9WV27
Gene Symbols:
ATP1A1, ATP1A4
Immunogen:
Synthetic peptide within Human ATP1A1 aa 39-83
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot
Clone:
ST0533
Conjugate:
Unconjugated
Gene:
ATP1A4
Gene Alias:
ATP1A1, ATP1A4, ATP1AL2, Atpa-1, ATPase Na+/K+ transporting subunit alpha 1, ATPase Na+/K+ transporting subunit alpha 4, ATPase, Na+/K+ transporting, alpha 1 polypeptide, ATPase, Na+/K+ transporting, alpha 4 polypeptide, ATPase, Na+/K+ transporting, alpha polypeptide-like 2, ATPase, Na+K+ transporting, alpha 1, BC010319, Na(+)/K(+) ATPase alpha-1 subunit, Na(+)/K(+) ATPase alpha-4 subunit, Na, K-ATPase, alpha-A catalytic polypeptide, Na,K-ATPase alpha-1 subunit, Na,K-ATPase catalytic subunit alpha-A protein, Na,K-ATPase subunit alpha-C, Na+/K+ ATPase 1, Na+/K+ ATPase 4, Na+/K+ ATPase alpha 4 subunit, Na+/K+ ATPase, alpha-D polypeptide, Nkaa1b, sodium pump 4, sodium pump subunit alpha-1, Sodium pump subunit alpha-4, sodium/potassium-transporting ATPase alpha-4 chain, sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-4, sodium-potassium ATPase catalytic subunit alpha-1, sodium-potassium ATPase catalytic subunit alpha-4, sodium-potassium-ATPase, alpha 1 polypeptide
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11928, 24211, 27222, 29132, 476, 480
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: p73
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O15350, Q9JJP2
Gene Symbols: TP73, Trp73
Immunogen: Recombinant protein within Human P73 aa 6-118
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: ST05-76
Conjugate: Unconjugated
Gene: TP73
Gene Alias: deltaNp73, OTTHUMP00000003479, OTTHUMP00000003480, p53-like transcription factor, p53-related protein, P73, RP23-254N4.10, TAp73, Tp73, transformation related protein 73, Trp73, Tumor protein p73
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 22062, 7161
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
p73
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O15350, Q9JJP2
Gene Symbols:
TP73, Trp73
Immunogen:
Recombinant protein within Human P73 aa 6-118
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
ST05-76
Conjugate:
Unconjugated
Gene:
TP73
Gene Alias:
deltaNp73, OTTHUMP00000003479, OTTHUMP00000003480, p53-like transcription factor, p53-related protein, P73, RP23-254N4.10, TAp73, Tp73, transformation related protein 73, Trp73, Tumor protein p73
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
22062, 7161
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid