PIMA532780

JAK1 Recombinant Rabbit Monoclonal Antibody (JM75-03), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532780-Each-of-1 In Stock ₹ 49,838.70

PIMA532780 - Each of 1

₹ 49,838.70

In Stock

Quantity

1

Base Price: ₹ 49,838.70

GST (18%): ₹ 8,970.966

Total Price: ₹ 58,809.666

Antigen

JAK1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P23458, P52332

Gene Symbols

JAK1

Immunogen

Synthetic peptide within Human JAK1 aa 621-670

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunohistochemistry, Western Blot

Clone

JM75-03

Conjugate

Unconjugated

Gene

JAK1

Gene Alias

AA960307, BAP004, C130039L05Rik, EC 2.7.10.2, Jak1, JAK-1, JAK1A, JAK1B, Janus kinase 1, Janus protein tyrosine kinase 1, JTK3, kinase Jak1, Tyrosine-protein kinase JAK1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16451, 3716, 84598

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha/beta and -gamma signal transduction pathways
  • Immunological stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK1
  • JAK1 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription
  • Upon ligand binding, JAK1 undergoes tyrosine phosphorylation and catalytic activation in an interdependent manner
  • Phosphorylation of tyrosine residues at positions 1022 and 1023 is believed to function in the activation of catalytic events.

Compare Similar Items

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Img

Thermo Scientific

PIMA532780

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Antigen:
JAK1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P23458, P52332

Gene Symbols:
JAK1

Immunogen:
Synthetic peptide within Human JAK1 aa 621-670

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
JM75-03

Conjugate:
Unconjugated

Gene:
JAK1

Gene Alias:
AA960307, BAP004, C130039L05Rik, EC 2.7.10.2, Jak1, JAK-1, JAK1A, JAK1B, Janus kinase 1, Janus protein tyrosine kinase 1, JTK3, kinase Jak1, Tyrosine-protein kinase JAK1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16451, 3716, 84598

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532783

--


Antigen:
GCLM

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O09172, P48507, P48508

Gene Symbols:
Gclm

Immunogen:
Recombinant protein within Human GCLM aa 225-274

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JM39-61

Conjugate:
Unconjugated

Gene:
Gclm

Gene Alias:
AI649393, gamma glutamylcysteine synthetase, gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, Gclm, Gcmc, GCS light chain, Glclr, glutamate cysteine ligase (gamma-glutamylcysteine synthetase), regulatory, glutamate cysteine ligase, modifier subunit, glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD), glutamate-cysteine ligase modifier subunit, glutamate--cysteine ligase modifier subunit, glutamate-cysteine ligase modifier subunit delta2 alternative splicing, glutamate-cysteine ligase regulatory protein, Glutamate--cysteine ligase regulatory subunit, glutamate-cysteine ligase, modifier subunit, GSC light chain, null

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14630, 2730, 29739

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532785

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Antigen:
FTO

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9C0B1

Gene Symbols:
Fto

Immunogen:
Synthetic peptide within Human FTO aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
JM98-30

Conjugate:
Unconjugated

Gene:
Fto

Gene Alias:
AlkB homolog 9, ALKBH9, alpha-ketoglutarate-dependent dioxygenase FTO, AW743446, BMIQ14, fat mass and obesity associated, fat mass and obesity-associated protein, fatso, FTO, GDFD, KIAA1752, m6A(m)-demethylase FTO, MGC5149, mKIAA1752, mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO, mRNA N(6)-methyladenosine demethylase FTO, Protein fatso, protein fto, RGD1305121, tRNA N1-methyl adenine demethylase FTO, U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO, U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
79068

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532788

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Antigen:
SATB2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q8VI24, Q9UPW6

Gene Symbols:
SATB2

Immunogen:
Synthetic peptide within Human SATB2 238-287

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JM52-44

Conjugate:
Unconjugated

Gene:
SATB2

Gene Alias:
DNA-binding protein SATB2, FLJ21474, FLJ32076, GLSS, KIAA1034, KIAA1034-like DNA binding protein, MGC119474, MGC119477, mKIAA1034, RGD1562369, SATB family member 2, SATB homeobox 2, SATB2, special AT-rich sequence binding protein 2, special AT-rich sequence-binding protein 2, two cut domains-containing homeodomain protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
212712, 23314, 501145

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid