PIMA532733

Thymidylate Synthase Recombinant Rabbit Monoclonal Antibody (JM33-20), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532733-Each-of-1 In Stock ₹ 45,646.26

PIMA532733 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Thymidylate Synthase

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P04818, P07607, P45352

Gene Symbols

TYMS

Immunogen

Synthetic peptide within Human Thymidylate Synthase aa 264-313

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunohistochemistry, Western Blot

Clone

JM33-20

Conjugate

Unconjugated

Gene

TYMS

Gene Alias

HST422, MGC88736, OK/SW-cl.29, Thymidylate synthase, thymidylate synthetase, TMS, TS, Tsase, Tyms, tysy

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

22171, 29261, 7298

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Thymidylate Synthase (TS) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis
  • TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors
  • Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate
  • Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Compare Similar Items

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Thermo Scientific

PIMA532733

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Antigen:
Thymidylate Synthase

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P04818, P07607, P45352

Gene Symbols:
TYMS

Immunogen:
Synthetic peptide within Human Thymidylate Synthase aa 264-313

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
JM33-20

Conjugate:
Unconjugated

Gene:
TYMS

Gene Alias:
HST422, MGC88736, OK/SW-cl.29, Thymidylate synthase, thymidylate synthetase, TMS, TS, Tsase, Tyms, tysy

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
22171, 29261, 7298

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532734

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Antigen:
MYST2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O95251, Q5SVQ0, Q810T5

Gene Symbols:
Kat7

Immunogen:
Recombinant protein within Human KAT7 aa 1-240

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
JM32-39

Conjugate:
Unconjugated

Gene:
Kat7

Gene Alias:
EC 2.3.1.48, HBO1, HBOa, histone acetyltransferase binding to ORC1, Histone acetyltransferase KAT7, histone acetyltransferase MYST2, K (lysine) acetyltransferase 7, K(lysine) acetyltransferase 7, Kat7, Lysine acetyltransferase 7, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, MYST histone acetyltransferase 2, MYST protein 2, MYST2, MYST-2, ZC2HC7

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11143, 217127, 303470

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532735

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Antigen:
CYP2D6

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P10635

Gene Symbols:
CYP2D6

Immunogen:
Recombinant protein within Human Cytochrome P450 2D6 aa 301-497

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JM44-23

Conjugate:
Unconjugated

Gene:
CYP2D6

Gene Alias:
AI303445, Cholesterol 25-hydroxylase, CPD6, CYP2D, Cyp2d10, Cyp2d-10, Cyp2d13, Cyp2d18, Cyp2d-18, Cyp2d22, Cyp2d3, Cyp2d-3, Cyp2d4, Cyp2d-4, Cyp2d4v1, Cyp2d4v2, Cyp2d6, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID10, CYPIID18, CYPIID3, CYPIID4, CYPIID6, Cytochrome P450 2D10, cytochrome P450 2d18, Cytochrome P450 2D-29, Cytochrome P450 2D3, cytochrome P450 2D-35, cytochrome P450 2D4, Cytochrome P450 2D6, cytochrome P450 family 2 subfamily D member 6, cytochrome P450, 2d10, cytochrome P450, family 2, subfamily d, polypeptide 10, cytochrome P450, family 2, subfamily d, polypeptide 13, cytochrome P450, family 2, subfamily d, polypeptide 22, cytochrome P450, family 2, subfamily d, polypeptide 3, cytochrome P450, family 2, subfamily d, polypeptide 4, cytochrome P450, family 2, subfamily d, polypeptide 6, cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2, cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2, cytochrome P450, subfamily 2D, polypeptide 6, cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1, cytochrome P450, subfamily IID, polypeptide 6, Cytochrome P450, subfamily IID3, Cytochrome P450, subfamily IID4, cytochrome P450-16-alpha, Cytochrome P450CB, Cytochrome P450-CMF3, cytochrome P450-DB1, Cytochrome P450-DB3, cytochrome P450-DB4, debrisoquine 4-hydroxylase, flavoprotein-linked monooxygenase, microsomal monooxygenase, nonfunctional cytochrome P450 2D6, P450 2D-29/2D-35, P450-2D, P450C2D, P450-CMF3, P450DB1, P450-DB1, P450-DB3, P450-DB4, testosterone 16-alpha hydroxylase, xenobiotic monooxygenase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1565

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532737

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Antigen:
Protein C

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P04070

Gene Symbols:
PROC

Immunogen:
Recombinant protein within Human Protein C aa 290-380

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JM93-61

Conjugate:
Unconjugated

Gene:
PROC

Gene Alias:
Activation peptide, Anticoagulant protein C, APC, autoprothrombin IIA, Blood coagulation factor XIV, EDQVDPRLIDGK, inactivator of coagulation factors Va, VIII, PC, prepro-protein C, Proc, PROC1, protein C, protein C (inactivator of coagulation factors Va and VIIIa), protein C prepropeptide, protein C, inactivator of coagulation factors Va and VIIIa, THPH3, THPH4, type I protein C, vitamin K-dependent protein C, Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5624

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid