PIMA532156

beta Arrestin 1 Recombinant Rabbit Monoclonal Antibody (ST51-08), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532156-Each-of-1 In Stock ₹ 44,619.54

PIMA532156 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

beta Arrestin 1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P29066, P49407, Q8BWG8

Gene Symbols

ARRB1

Immunogen

Synthetic peptide within Human beta Arrestin 1 aa 1-50

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

ST51-08

Conjugate

Unconjugated

Gene

ARRB1

Gene Alias

1200006I17Rik, ARB1, ARR1, ARRB1, ARRB1 protein, arrdc1, arrestin, arrestin 2, arrestin beta 1, arrestin beta-1, arrestin, beta 1, arrestin-2, AW208571, BARRES, beta-arrestin, beta-arrestin1, beta-arrestin-1, G430100A01Rik, Non-visual arrestin-2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

109689, 25387, 408

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Beta Arrestin 1 is a member of a family of proteins widely expressed but especially abundant in the central nervous system
  • Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling and mediates agonist-dependent desensitization and internalization of Gprotein-coupled receptors (GPCRs, e.g., beta 2-adrenergic receptor)
  • After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G-protein receptor kinases (GRKs) on serine residues
  • Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane
  • Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532156

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Antigen:
beta Arrestin 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P29066, P49407, Q8BWG8

Gene Symbols:
ARRB1

Immunogen:
Synthetic peptide within Human beta Arrestin 1 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
ST51-08

Conjugate:
Unconjugated

Gene:
ARRB1

Gene Alias:
1200006I17Rik, ARB1, ARR1, ARRB1, ARRB1 protein, arrdc1, arrestin, arrestin 2, arrestin beta 1, arrestin beta-1, arrestin, beta 1, arrestin-2, AW208571, BARRES, beta-arrestin, beta-arrestin1, beta-arrestin-1, G430100A01Rik, Non-visual arrestin-2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
109689, 25387, 408

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532158

--


Antigen:
Phospho-PP2A alpha (Tyr307)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P63330, P63331, P67775

Gene Symbols:
PPP2CA

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr307 of Human PP2A aa 260-309

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
ST49-05

Conjugate:
Unconjugated

Gene:
PPP2CA

Gene Alias:
B55-GAMMA, hypothetical protein, IMYPNO, IMYPNO1, Methyl-PPP2CA, MGC33570, PP2A, PP2A alpha, PP2A C terminal, PP2A L9, PP2A Leucine 9, Pp2a1, PP2A-alpha, PP2Ac, PP2CA, PP2Calpha, Ppp2ca, PR52, PR55G, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform, protein phosphatase 2 catalytic subunit alpha, protein phosphatase 2, catalytic subunit, alpha isoform, protein phosphatase 2, catalytic subunit, alpha isozyme, protein phosphatase 2,catalytic subunit alpha isozyme, protein phosphatase 2A alpha subunit, protein phosphatase 2A catalytic subunit alpha isoform, protein phosphatase 2a, catalytic subunit, alpha isoform, protein phosphatase type 2A catalytic subunit, protein phosphatase-2A, protein phosphatase-2A-alpha, R75353, replication protein C, RP-C, serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19052, 24672, 5515

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532159

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Antigen:
Phospho-JNK1/JNK2/JNK3 (Thr183, Thr221)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P45983, P45984, P49185, P49186, P49187, P53779, Q61831, Q91Y86, Q9WTU6

Gene Symbols:
MAPK10, MAPK8, MAPK9

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Thr183 + Thr183 + Thr221 of Human JNK1/2/3 aa 161-204

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
ST500

Conjugate:
Unconjugated

Gene:
MAPK9

Gene Alias:
AI849689, AI851083, C230008H04Rik, c-Jun kinase 2, c-Jun N-terminal kinase 1, c-Jun N-terminal kinase 2, c-Jun N-terminal kinase 3, FLJ12099, FLJ33785, hypothetical protein LOC569698, janus kinase 1, janus kinase 2, JNK, JNK 46, JNK 55, JNK/SAPK alpha, JNK1, JNK1 beta1 protein kinase, JNK1A2, Jnk2, JNK21B1/2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, Jnk3, JNK3 alpha protein kinase, JNK3 beta1 protein kinase, JNK3 beta2 protein kinase, JNK3A, JNK3B1, JNK3B2, JNK-46, JNK-55, Jun kinase, JUN N-terminal kinase, MAP kinase 10, MAP kinase 8, MAP kinase 9, MAP kinase p49 3F12, MAPK 10, MAPK 8, MAPK 9, Mapk10, Mapk8, Mapk9, MGC137545 protein, MGC50974, Mi, mitogen activated protein kinase 10, mitogen activated protein kinase 8, mitogen activated protein kinase 9, mitogen-activated protein kinase 10, Mitogen-activated protein kinase 8, mitogen-activated protein kinase 8 isoform JNK1 alpha1, mitogen-activated protein kinase 8 isoform JNK1 beta2, mitogen-activated protein kinase 9, MK10, p493F12, p54 gamma, p54a, p54-alpha, p54aSAPK, p54-beta, p54bSAPK, Phospho-JNK, PRKM10, Prkm8, PRKM9, protein kinase mitogen-activated 8, protein kinase, mitogen-activated 9, SAPb, SAPK, SAPK gamma, SAPK(beta), SAPK/Erk/kinase 2, SAPK1, SAPK1a, SAPK1B, SAPK1c, SAPK-alpha, SAPK-beta, SAPKC, Serk2, si:ch211-247j9.2, stress activated protein kinase alpha II, Stress activated protein kinase beta, stress-activated protein kinase 1, stress-activated protein kinase 1a, Stress-activated protein kinase 1b, stress-activated protein kinase 1c, Stress-activated protein kinase JNK1, stress-activated protein kinase JNK2, Stress-activated protein kinase JNK3, zgc:123234

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532160

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Antigen:
PRMT5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O14744, Q8CIG8

Gene Symbols:
PRMT5

Immunogen:
Synthetic peptide within Human PRMT5 aa 48-91

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
ST51-06

Conjugate:
Unconjugated

Gene:
PRMT5

Gene Alias:
72 kDa ICln-binding protein, EC 2.1.1.125, histone-arginine N-methyltransferase PRMT5, HMT1 hnRNP methyltransferase-like 5, HRMT1L5, hypothetical protein, I79_013398, IBP72, Jak-binding protein 1, JBP1, PRMT5, protein arginine methyltransferase 5, protein arginine N-methyltransferase 5, Protein arginine N-methyltransferase 5, N-terminally processed, protein arginine N-methyltransferase 5-like, shk1 kinase-binding protein 1 homolog, Skb1, SKB1 homolog, SKB1Hs

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10419, 27374, 364382

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid