PIMA532161

PKC beta-2 Recombinant Rabbit Monoclonal Antibody (ST48-06), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532161-Each-of-1 In Stock ₹ 44,619.54

PIMA532161 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

PKC beta-2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P05771, P68403, P68404

Gene Symbols

PRKCB

Immunogen

Synthetic peptide within Human PKC beta 2 aa 615-660

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

ST48-06

Conjugate

Unconjugated

Gene

PRKCB

Gene Alias

A130082F03Rik, PKCB, PKC-B, PKC-beta, Prkcb, PRKCB1, Prkcb2, protein kinase C beta, protein kinase C beta I, protein kinase C beta II, protein kinase C beta type, protein kinase C beta-II, protein kinase C, beta, protein kinase C, beta 1, protein kinase C, beta 1 polypeptide

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18751, 25023, 5579

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • The PKC family of serine/threonine kinases, including PRKCB2 (PKC beta II), is activated intracellularly by signal transduction pathways
  • In humans, at least 12 different PKC polypeptides have been identified
  • These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity
  • PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent
  • Protein kinase C (PKC) can be activated by calcium and second messenger diacylglycerol
  • PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways
  • PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters
  • Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells
  • The protein encoded by this gene is one of the PKC family members
  • This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption
  • Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress
  • Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA532161

--


Antigen:
PKC beta-2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P05771, P68403, P68404

Gene Symbols:
PRKCB

Immunogen:
Synthetic peptide within Human PKC beta 2 aa 615-660

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
ST48-06

Conjugate:
Unconjugated

Gene:
PRKCB

Gene Alias:
A130082F03Rik, PKCB, PKC-B, PKC-beta, Prkcb, PRKCB1, Prkcb2, protein kinase C beta, protein kinase C beta I, protein kinase C beta II, protein kinase C beta type, protein kinase C beta-II, protein kinase C, beta, protein kinase C, beta 1, protein kinase C, beta 1 polypeptide

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18751, 25023, 5579

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532162

--


Antigen:
HSP60

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P10809, P63038, P63039

Gene Symbols:
HSPD1

Immunogen:
Synthetic peptide within Human Hsp60 aa 421-457

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
ST48-04

Conjugate:
Unconjugated

Gene:
HSPD1

Gene Alias:
60 kDa chaperonin, 60 kDa heat shock protein, 60 kDa heat shock protein, mitochondrial, 60kDa, Chaperonin 60, CPN60, GROEL, heat shock 60kD protein 1 (chaperonin), heat shock 60kDa protein 1, heat shock 60kDa protein 1 (chaperonin), Heat shock protein, heat shock protein 1 (chaperonin), heat shock protein 60, heat shock protein 60 (liver), heat shock protein 65, heat shock protein family D (Hsp60) member 1, heat shock protein, 60 kDa, HLD4, HSP, Hsp60, HSP-60, Hsp60s1, HSP65, HSP-65, Hspd1, Hspd1-30p, HuCHA60, hypothetical protein, I79_011398, mitochondrial matrix protein P1, P1 protein, P60 lymphocyte protein, RCJMB04_7g5, short heat shock protein 60 Hsp60s1, SPG13, Unknown (protein for IMAGE:7943409)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15510, 3329, 63868

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532163

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Antigen:
beta Tubulin 2,4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P04350, P68371, P68372, P85108, Q13885, Q3KRE8, Q6P9T8, Q7TMM9, Q9BVA1, Q9CWF2, Q9D6F9

Gene Symbols:
Tubb2a, Tubb2b, TUBB4A, TUBB4B

Immunogen:
Synthetic peptide within Human beta II Tubulin aa 407-445

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
ST52-04

Conjugate:
Unconjugated

Gene:
TUBB4A

Gene Alias:
2410129E14Rik, 4930542G03Rik, AI325297, bA506K6.1, Beta2, beta-5, beta-tubulin T beta15 (aa 1-445), brdp, CDCBM5, class II beta-tubulin isotype, class IIa beta-tubulin, class IIb beta-tubulin, class IVb beta tubulin, class IVb beta-tubulin, dystonia 4, torsion (autosomal dominant), DYT4, M(beta)2, M(beta)4, novel tubulin protein, PMGYSA, RGD1309427, t beta-15, TUBB, Tubb2, TUBB2A, tubb2a {ECO:0000250, Tubb2b, TUBB2C, Tubb2c1, Tubb4, Tubb4a, Tubb4b, TUBB5, Tubulin 5 beta, tubulin beta, tubulin beta 2A class IIa, tubulin beta 2B class IIb, tubulin beta 4A class IVa, tubulin beta 4B class IVb, Tubulin beta class IIa, Tubulin beta-2 chain, tubulin beta-2A chain, Tubulin beta-2B chain, tubulin beta-2C chain, Tubulin beta-4 chain, tubulin beta-4A chain, Tubulin beta-4B chain, tubulin, beta 2, tubulin, beta 2A class IIa, tubulin, beta 2B class IIb, tubulin, beta 2C, tubulin, beta 2c1, tubulin, beta 4, tubulin, beta 4 class IVa, tubulin, beta 4A class IVa, tubulin, beta 4B class IVb, tubulin, beta polypeptide, tubulin, beta polypeptide 2, tubulin, beta polypeptide paralog, tubulin, beta, 2, tubulin, beta, 5, UniProtKB:Q7TMM9}

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10382, 10383, 22151, 22153, 227613, 291081, 29213, 296554, 347733, 498736, 7280, 73710

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532165

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Antigen:
Phospho-MEK1 (Ser218, Ser222)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q02750

Gene Symbols:
Map2k1

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser218 and 222 of Human MEK1 aa 200-249

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
ST0490

Conjugate:
Unconjugated

Gene:
Map2k1

Gene Alias:
CFC3, dual specificity mitogen activated protein kinase kinase 1, dual specificity mitogen-activated protein kinase kinase 1, EC 2.7.12.2, ERK activator kinase 1, kinase MEK1, MAP kinase kinase 1, MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2), MAP kinase/Erk kinase 1, Map2k1, map2k1.L, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, Mek1, MEK2, mek-2, MEKK1, mitogen activated protein kinase kinase 1, mitogen-activated protein kinase kinase 1, mitogen-activated protein kinase kinase 1 L homeolog, MKK (Thr292), MKK (Thr386), MKK1, MKK2, MP2K1, Prkmk1, PRKMK2, protein kinase, mitogen activated, kinase 1, p45, protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1), XELAEV_18018447mg

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5604

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid