PIMA532418

MEKK3 Recombinant Rabbit Monoclonal Antibody (SD0839), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532418-Each-of-1 In Stock ₹ 45,646.26

PIMA532418 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

MEKK3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q61084, Q99759

Gene Symbols

Map3k3

Immunogen

Synthetic peptide within Human MEKK3 aa 1-50

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SD0839

Conjugate

Unconjugated

Gene

Map3k3

Gene Alias

AW548911, MAP/ERK kinase kinase 3, MAP3K3, MAPK/ERK kinase kinase 3, MAPKKK3, MEK kinase 3, MEKK 3, Mekk3, mitogen activated protein kinase kinase kinase 3, mitogen-activated protein kinase kinase kinase 3, mKIAA4031

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

26406, 303604, 4215

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • MAP3K3 (MEKK3) directly regulates MAPK8 and extracellular signal-regulated protein kinase (ERK) pathways by phosphorylating multiple MAP2Ks
  • Northern blot analysis revealed a 4
  • 6-kb transcript that appears to be ubiquitously expressed
  • This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway
  • In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway
  • Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532418

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Antigen:
MEKK3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q61084, Q99759

Gene Symbols:
Map3k3

Immunogen:
Synthetic peptide within Human MEKK3 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SD0839

Conjugate:
Unconjugated

Gene:
Map3k3

Gene Alias:
AW548911, MAP/ERK kinase kinase 3, MAP3K3, MAPK/ERK kinase kinase 3, MAPKKK3, MEK kinase 3, MEKK 3, Mekk3, mitogen activated protein kinase kinase kinase 3, mitogen-activated protein kinase kinase kinase 3, mKIAA4031

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
26406, 303604, 4215

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532420

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Antigen:
Cdc34

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P49427, Q8CFI2

Gene Symbols:
CDC34

Immunogen:
Recombinant protein within Human Cdc34 aa 1-236

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone:
JJ086-07

Conjugate:
Unconjugated

Gene:
CDC34

Gene Alias:
(E3-independent) E2 ubiquitin-conjugating enzyme R1, AI327276, CDC34, cell division cycle 34, cell division cycle 34 homolog, E2 ubiquitin-conjugating enzyme R1, E2-CDC34, serine protease, UBC3, UBCH3, UBE2R1, ubiquitin carrier protein, ubiquitin conjugating enzyme E2 R1, ubiquitin-conjugating enzyme Cdc34, ubiquitin-conjugating enzyme E2 R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
216150, 299602, 997

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532421

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Antigen:
HSPB8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9EPX0, Q9JK92, Q9UJY1

Gene Symbols:
HSPB8

Immunogen:
Synthetic peptide within Human Hsp20 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JJ08-53

Conjugate:
Unconjugated

Gene:
HSPB8

Gene Alias:
Alpha-crystallin C chain, AU018630, AW413033, CMT2L, Cryac, crystallin, alpha C, D5Ucla4, DHMN 2, DHMN2, E2IG1, E2-induced gene 1 protein, H11, H11K, heat shock 22kDa protein 8, heat shock 27kDa protein 8, Heat shock protein, heat shock protein 8, heat shock protein B8, heat shock protein beta-8, heat shock protein family B (small) member 8, HMN 2, HMN2, HMN2A, HSB8, HSP, HSP20-like, Hsp22, HSPB 8, Hspb8, OTTHUMP00000239768, PP1629, Protein kinase H11, small stress protein-like protein HSP22

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
113906, 26353, 80888

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532422

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Antigen:
HDAC8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9BY41

Gene Symbols:
HDAC8

Immunogen:
Synthetic peptide within Human HDAC8 aa 51-100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JJ0845

Conjugate:
Unconjugated

Gene:
HDAC8

Gene Alias:
2610007D20Rik, CDA07, CDLS5, HD8, Hdac8, HDACL1, histone deacetylase 8, histone deacetylase-like 1, MRXS6, RGD1562895, RPD3, WTS

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55869

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid