PIMA532420

Cdc34 Recombinant Rabbit Monoclonal Antibody (JJ086-07), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532420-Each-of-1 In Stock ₹ 45,646.26

PIMA532420 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Cdc34

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P49427, Q8CFI2

Gene Symbols

CDC34

Immunogen

Recombinant protein within Human Cdc34 aa 1-236

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone

JJ086-07

Conjugate

Unconjugated

Gene

CDC34

Gene Alias

(E3-independent) E2 ubiquitin-conjugating enzyme R1, AI327276, CDC34, cell division cycle 34, cell division cycle 34 homolog, E2 ubiquitin-conjugating enzyme R1, E2-CDC34, serine protease, UBC3, UBCH3, UBE2R1, ubiquitin carrier protein, ubiquitin conjugating enzyme E2 R1, ubiquitin-conjugating enzyme Cdc34, ubiquitin-conjugating enzyme E2 R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

216150, 299602, 997

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins
  • In vitro catalyzes 'Lys-48'-linked polyubiquitination
  • Cooperates with the E2 UBCH5C and the SCF (FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation
  • Performs ubiquitin chain elongation building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin
  • UBE2D3 acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin
  • Cooperates with the SCF (SKP2) E3 ligase complex to regulate cell proliferation through ubiquitination and degradation of MYBL2 and KIP1
  • Involved in ubiquitin conjugation and degradation of CREM isoform ICERIIgamma and ATF15 resulting in abrogation of ICERIIgamma- and ATF5-mediated repression of cAMP-induced transcription during both meiotic and mitotic cell cycles
  • Involved in the regulation of the cell cycle G2/M phase through its targeting of the WEE1 kinase for ubiquitination and degradation
  • Also involved in the degradation of beta-catenin
  • Is target of human herpes virus 1 protein ICP0, leading to ICP0-dependent dynamic interaction with proteasomes.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532420

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Antigen:
Cdc34

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P49427, Q8CFI2

Gene Symbols:
CDC34

Immunogen:
Recombinant protein within Human Cdc34 aa 1-236

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone:
JJ086-07

Conjugate:
Unconjugated

Gene:
CDC34

Gene Alias:
(E3-independent) E2 ubiquitin-conjugating enzyme R1, AI327276, CDC34, cell division cycle 34, cell division cycle 34 homolog, E2 ubiquitin-conjugating enzyme R1, E2-CDC34, serine protease, UBC3, UBCH3, UBE2R1, ubiquitin carrier protein, ubiquitin conjugating enzyme E2 R1, ubiquitin-conjugating enzyme Cdc34, ubiquitin-conjugating enzyme E2 R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
216150, 299602, 997

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532421

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Antigen:
HSPB8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9EPX0, Q9JK92, Q9UJY1

Gene Symbols:
HSPB8

Immunogen:
Synthetic peptide within Human Hsp20 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JJ08-53

Conjugate:
Unconjugated

Gene:
HSPB8

Gene Alias:
Alpha-crystallin C chain, AU018630, AW413033, CMT2L, Cryac, crystallin, alpha C, D5Ucla4, DHMN 2, DHMN2, E2IG1, E2-induced gene 1 protein, H11, H11K, heat shock 22kDa protein 8, heat shock 27kDa protein 8, Heat shock protein, heat shock protein 8, heat shock protein B8, heat shock protein beta-8, heat shock protein family B (small) member 8, HMN 2, HMN2, HMN2A, HSB8, HSP, HSP20-like, Hsp22, HSPB 8, Hspb8, OTTHUMP00000239768, PP1629, Protein kinase H11, small stress protein-like protein HSP22

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
113906, 26353, 80888

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532422

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Antigen:
HDAC8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9BY41

Gene Symbols:
HDAC8

Immunogen:
Synthetic peptide within Human HDAC8 aa 51-100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JJ0845

Conjugate:
Unconjugated

Gene:
HDAC8

Gene Alias:
2610007D20Rik, CDA07, CDLS5, HD8, Hdac8, HDACL1, histone deacetylase 8, histone deacetylase-like 1, MRXS6, RGD1562895, RPD3, WTS

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55869

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532423

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Antigen:
Cytokeratin 2e

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P35908

Gene Symbols:
KRT2

Immunogen:
Recombinant protein within Human Cytokeratin 2e aa 273-442

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
JJ201-8

Conjugate:
Unconjugated

Gene:
KRT2

Gene Alias:
BB005427, CK 2e, CK-2e, Cytokeratin-2e, epithelial keratin-2e, K2e, Kb2, keratin 2, keratin 2 epidermis, keratin 2, type II, keratin 2e, keratin complex 2, basic, gene 17, keratin complex 2, gene 17, keratin, type II cytoskeletal 2 epidermal, Keratin-2 epidermis, keratin-2e, KRT2, krt2 {ECO:0000250, Krt2-17, Krt2-2, KRT2A, Krt2e, KRTE, MGC116967, MGC116968, type II keratin Kb2, type-II keratin Kb2, UniProtKB:P35908}

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3849

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid