PIMA532422

HDAC8 Recombinant Rabbit Monoclonal Antibody (JJ0845), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532422-Each-of-1 In Stock ₹ 45,646.26

PIMA532422 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

HDAC8

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q9BY41

Gene Symbols

HDAC8

Immunogen

Synthetic peptide within Human HDAC8 aa 51-100

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

JJ0845

Conjugate

Unconjugated

Gene

HDAC8

Gene Alias

2610007D20Rik, CDA07, CDLS5, HD8, Hdac8, HDACL1, histone deacetylase 8, histone deacetylase-like 1, MRXS6, RGD1562895, RPD3, WTS

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

55869

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin
  • The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones
  • Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA
  • Conversely, the deacetylation of histones is associated with transcriptional silencing
  • Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250
  • Mammalian HDAC8, isolated from human kidney, is a histone deacetylase that shares homology to other HDACs but has different tissue distribution
  • HDAC8 is localized to the nucleus and plays a role in the development of a broad range of tissues and in the etiology of cancer.

Compare Similar Items

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Img

Thermo Scientific

PIMA532422

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Antigen:
HDAC8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9BY41

Gene Symbols:
HDAC8

Immunogen:
Synthetic peptide within Human HDAC8 aa 51-100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JJ0845

Conjugate:
Unconjugated

Gene:
HDAC8

Gene Alias:
2610007D20Rik, CDA07, CDLS5, HD8, Hdac8, HDACL1, histone deacetylase 8, histone deacetylase-like 1, MRXS6, RGD1562895, RPD3, WTS

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55869

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532423

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Antigen:
Cytokeratin 2e

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P35908

Gene Symbols:
KRT2

Immunogen:
Recombinant protein within Human Cytokeratin 2e aa 273-442

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
JJ201-8

Conjugate:
Unconjugated

Gene:
KRT2

Gene Alias:
BB005427, CK 2e, CK-2e, Cytokeratin-2e, epithelial keratin-2e, K2e, Kb2, keratin 2, keratin 2 epidermis, keratin 2, type II, keratin 2e, keratin complex 2, basic, gene 17, keratin complex 2, gene 17, keratin, type II cytoskeletal 2 epidermal, Keratin-2 epidermis, keratin-2e, KRT2, krt2 {ECO:0000250, Krt2-17, Krt2-2, KRT2A, Krt2e, KRTE, MGC116967, MGC116968, type II keratin Kb2, type-II keratin Kb2, UniProtKB:P35908}

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3849

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532424

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Antigen:
Cdc37

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q16543, Q61081, Q63692

Gene Symbols:
CDC37

Immunogen:
Synthetic peptide within Human Cdc37 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
JJ087-06

Conjugate:
Unconjugated

Gene:
CDC37

Gene Alias:
CDC 37, CDC37, CDC37 (cell division cycle 37 S. cerevisiae homolog), CDC37 (cell division cycle 37, S. cerevisiae, homolog), CDC37 cell division cycle 37 homolog, Cdc37 homolog, CDC37 protein, CDC37A, Cdc37p, Cell division control protein 37, cell division cycle 37, cell division cycle 37 homolog, hsp90 chaperone protein kinase-targeting subunit, Hsp90 co-chaperone Cdc37, Hsp90 co-chaperone Cdc37, N-terminally processed, p50, P50CDC37, SMO1, YD9489.03, YDR168W

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11140, 114562, 12539

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532427

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Antigen:
SUMO2/SUMO3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P55854, P61956, P61957, P61959, Q5XIF4, Q9Z172

Gene Symbols:
SUMO2, Sumo3

Immunogen:
Synthetic peptide within Human Sumo 3 aa 11-60

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JJ087-04

Conjugate:
Unconjugated

Gene:
SUMO2

Gene Alias:
2810014B19Rik, D10Ertd345e, GMP1, HSMT3, I79_000932, MIF2 suppressor, Sentrin, sentrin 2, sentrin-2, small ubiquitin-like modifier 2, small ubiquitin-like modifier 3, small ubiquitin-like modifier 3 L homeolog, small ubiquitin-related modifier 2, Small ubiquitin-related modifier 3, Smt3, SMT3 (supressor of mif two, 3) homolog 1, SMT3 homolog 1, SMT3 homolog 2, SMT3 homolog 3, SMT3 suppressor of mif two 3 homolog 1, SMT3 suppressor of mif two 3 homolog 2, SMT3 suppressor of mif two 3 homolog 2 (yeast), SMT3 suppressor of mif two 3 homolog 3, SMT3 suppressor of mif two 3 homolog 3 (yeast), SMT3 supressor of mif two 3 homolog 2, SMT3A, Smt3B, SMT3C, SMT3H1, SMT3H2, SMT3H3, SUMO-1, SUMO2, SUMO-2, Sumo3, SUMO-3, sumo3.L, Ubiquitin-like protein SMT3A, ubiquitin-like protein SMT3B, UBL1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
170930, 20610, 499417, 6612, 6613, 690244

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid