PIMA532411

HDAC8 Recombinant Rabbit Monoclonal Antibody (SD082-07), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532411-Each-of-1 In Stock ₹ 45,646.26

PIMA532411 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

HDAC8

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

B1WC68, Q8VH37, Q9BY41

Gene Symbols

HDAC8

Immunogen

Synthetic peptide within Human HDAC8 aa 61-110

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Western Blot

Clone

SD082-07

Conjugate

Unconjugated

Gene

HDAC8

Gene Alias

2610007D20Rik, CDA07, CDLS5, HD8, Hdac8, HDACL1, histone deacetylase 8, histone deacetylase-like 1, MRXS6, RGD1562895, RPD3, WTS

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

363481, 55869, 70315

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin
  • The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones
  • Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA
  • Conversely, the deacetylation of histones is associated with transcriptional silencing
  • Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250
  • Mammalian HDAC8, isolated from human kidney, is a histone deacetylase that shares homology to other HDACs but has different tissue distribution
  • HDAC8 is localized to the nucleus and plays a role in the development of a broad range of tissues and in the etiology of cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532411

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Antigen:
HDAC8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
B1WC68, Q8VH37, Q9BY41

Gene Symbols:
HDAC8

Immunogen:
Synthetic peptide within Human HDAC8 aa 61-110

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
SD082-07

Conjugate:
Unconjugated

Gene:
HDAC8

Gene Alias:
2610007D20Rik, CDA07, CDLS5, HD8, Hdac8, HDACL1, histone deacetylase 8, histone deacetylase-like 1, MRXS6, RGD1562895, RPD3, WTS

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
363481, 55869, 70315

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532412

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Antigen:
Collagen VI

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P12109, Q04857

Gene Symbols:
COL6A1

Immunogen:
Recombinant protein within Human Collagen VI aa 17-255

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SD83-03

Conjugate:
Unconjugated

Gene:
COL6A1

Gene Alias:
AI747156, alpha 1 (VI) chain (61 AA), BTHLM1, Col6a1, Col6a-1, Col6a2, Col6a-2, Collagen alpha-1(VI) chain, collagen alpha-2(VI) chain, collagen type VI alpha 1, collagen type VI alpha 2, collagen VI, alpha-1 polypeptide, collagen VI, alpha-2 polypeptide, collagen, type VI, alpha 1, collagen, type VI, alpha 2, human mRNA for collagen VI alpha-2 C-terminal globular domain, OPLL, PP3610, procollagen, type VI, alpha 1, procollagen, type VI, alpha 2, RGD1565398, UCHMD1, UCMD1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12833, 1291, 294337

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532416

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Antigen:
Phospho-Cdc6 (Ser54)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q99741

Gene Symbols:
CDC6

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser54 of Human Cdc6 aa 41-90

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
SD08-47

Conjugate:
Unconjugated

Gene:
CDC6

Gene Alias:
CDC18(S.pombe), CDC18L, cdc18-related protein, CDC6, CDC6 cell division cycle 6 homolog, CDC6-related protein, Cell division control protein 6 homolog, cell division cycle 6, cell division cycle 6 homolog, HsCDC18, HsCDC6, p62(cdc6)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
990

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532418

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Antigen:
MEKK3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q61084, Q99759

Gene Symbols:
Map3k3

Immunogen:
Synthetic peptide within Human MEKK3 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SD0839

Conjugate:
Unconjugated

Gene:
Map3k3

Gene Alias:
AW548911, MAP/ERK kinase kinase 3, MAP3K3, MAPK/ERK kinase kinase 3, MAPKKK3, MEK kinase 3, MEKK 3, Mekk3, mitogen activated protein kinase kinase kinase 3, mitogen-activated protein kinase kinase kinase 3, mKIAA4031

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
26406, 303604, 4215

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid