PIMA532357

CDK6 Recombinant Rabbit Monoclonal Antibody (SD20-50), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532357-Each-of-1 In Stock ₹ 52,448.28

PIMA532357 - Each of 1

₹ 52,448.28

In Stock

Quantity

1

Base Price: ₹ 52,448.28

GST (18%): ₹ 9,440.69

Total Price: ₹ 61,888.97

Antigen

CDK6

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q00534

Gene Symbols

CDK6

Immunogen

Synthetic peptide within Human Cdk6 aa 277-326

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SD20-50

Conjugate

Unconjugated

Gene

CDK6

Gene Alias

5830411I20, AI504062, CDK6, CDKN6, Cell division protein kinase 6, CR2 protein kinase, Crk2, cyclin dependent kinase 6, cyclin-dependent kinase 6, MCPH12, MGC59692, PLSTIRE, Serine/threonine-protein kinase PLSTIRE

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1021

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • CDK6 functions as a cell-cycle initiator protein
  • This protein is coexpressed and copurified with CyclinD1
  • They are critical regulators of cell cycle progression
  • The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression
  • CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles
  • Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).

Compare Similar Items

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Img

Thermo Scientific

PIMA532357

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Antigen:
CDK6

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q00534

Gene Symbols:
CDK6

Immunogen:
Synthetic peptide within Human Cdk6 aa 277-326

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SD20-50

Conjugate:
Unconjugated

Gene:
CDK6

Gene Alias:
5830411I20, AI504062, CDK6, CDKN6, Cell division protein kinase 6, CR2 protein kinase, Crk2, cyclin dependent kinase 6, cyclin-dependent kinase 6, MCPH12, MGC59692, PLSTIRE, Serine/threonine-protein kinase PLSTIRE

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1021

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532358

--


Antigen:
Phospho-Cyclin E (Thr77)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P24864

Gene Symbols:
CCNE1

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Thr77 of Human Cyclin E1 aa 51-100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SD2025

Conjugate:
Unconjugated

Gene:
CCNE1

Gene Alias:
AW538188, Ccne, Ccne1, CycE1, CYCLE, cyclin E, cyclin E1, cyclin Es, cyclin Et, E-S, G1/S-specific cyclin-E1, pCCNE1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
898

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532359

--


Antigen:
Phospho-SMAD2 (Ser250)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O70436, Q15796, Q62432

Gene Symbols:
SMAD2

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser250 of Human Smad2 aa 221-270

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
SD207-1

Conjugate:
Unconjugated

Gene:
SMAD2

Gene Alias:
7120426M23Rik, EGK_09664, hMAD-2, hSMAD2, JV18, JV18-1, MAD, MAD homolog 2, Mad protein homolog, Madh2, Madr2, Mad-related protein 2, MGC22139, MGC34440, mMad2, mother against DPP homolog 2, mothers against decapentaplegic homolog 2, Mothers against decapentaplegic-like protein 2, mothers against DPP homolog 2, pSMAD2, Sma- and Mad-related protein 2, SMAD, SMAD 2, SMAD family member 2, SMAD, mothers against DPP homolog 2, Smad2, Smad-2, Smad2Deltaexon3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17126, 29357, 4087

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532360

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Antigen:
AP2M1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P84091, P84092, Q96CW1

Gene Symbols:
AP2M1

Immunogen:
Synthetic peptide within Human AP2M1 aa 351-400

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SD0746

Conjugate:
Unconjugated

Gene:
AP2M1

Gene Alias:
adapter-related protein complex 2 mu subunit, adapter-related protein complex 2 subunit mu, adaptin-mu2, Adaptor protein complex AP-2 subunit mu, adaptor related protein complex 2 mu 1 subunit, adaptor related protein complex 2 subunit mu 1, adaptor related protein complex 2, mu 1 subunit, adaptor-related protein complex 2 subunit mu, adaptor-related protein complex 2, mu 1 subunit, AP-2 complex subunit mu, AP-2 mu 2 chain, AP-2 mu chain, Ap2m1, AP50, Clapm1, clathrin adaptor complex AP2, mu subunit, Clathrin assembly protein complex 2 medium chain, clathrin assembly protein complex 2 mu medium chain, clathrin coat adaptor protein AP50, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP50, clathrin-associated/assembly/adaptor protein, medium 1, coat assembly protein complex 50 kD, HA2 50 kDA subunit, KIAA0109, mu2, Mu2-adaptin, Plasma membrane adaptor AP-2 50 kDa protein, plasma membrane adaptor AP-2 50kDA protein, QtsA-16673, unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
116563, 1173, 11773

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid