PIMA532358
Phospho-Cyclin E (Thr77) Recombinant Rabbit Monoclonal Antibody (SD2025), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532358-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA532358 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
Phospho-Cyclin E (Thr77)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P24864
Gene Symbols
CCNE1
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Thr77 of Human Cyclin E1 aa 51-100
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SD2025
Conjugate
Unconjugated
Gene
CCNE1
Gene Alias
AW538188, Ccne, Ccne1, CycE1, CYCLE, cyclin E, cyclin E1, cyclin Es, cyclin Et, E-S, G1/S-specific cyclin-E1, pCCNE1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
898
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Cyclin E belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle
- Cyclins function as regulators of CDK kinases
- Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event
- Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition
- This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase
- Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis
- This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB
- Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described
- Two additional splice variants were reported but detailed nucleotide sequence information is not yet available.
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Antigen: Phospho-Cyclin E (Thr77)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P24864
Gene Symbols: CCNE1
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Thr77 of Human Cyclin E1 aa 51-100
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SD2025
Conjugate: Unconjugated
Gene: CCNE1
Gene Alias: AW538188, Ccne, Ccne1, CycE1, CYCLE, cyclin E, cyclin E1, cyclin Es, cyclin Et, E-S, G1/S-specific cyclin-E1, pCCNE1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 898
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-Cyclin E (Thr77)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P24864
Gene Symbols:
CCNE1
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Thr77 of Human Cyclin E1 aa 51-100
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SD2025
Conjugate:
Unconjugated
Gene:
CCNE1
Gene Alias:
AW538188, Ccne, Ccne1, CycE1, CYCLE, cyclin E, cyclin E1, cyclin Es, cyclin Et, E-S, G1/S-specific cyclin-E1, pCCNE1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
898
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-SMAD2 (Ser250)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O70436, Q15796, Q62432
Gene Symbols: SMAD2
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser250 of Human Smad2 aa 221-270
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Western Blot
Clone: SD207-1
Conjugate: Unconjugated
Gene: SMAD2
Gene Alias: 7120426M23Rik, EGK_09664, hMAD-2, hSMAD2, JV18, JV18-1, MAD, MAD homolog 2, Mad protein homolog, Madh2, Madr2, Mad-related protein 2, MGC22139, MGC34440, mMad2, mother against DPP homolog 2, mothers against decapentaplegic homolog 2, Mothers against decapentaplegic-like protein 2, mothers against DPP homolog 2, pSMAD2, Sma- and Mad-related protein 2, SMAD, SMAD 2, SMAD family member 2, SMAD, mothers against DPP homolog 2, Smad2, Smad-2, Smad2Deltaexon3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17126, 29357, 4087
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-SMAD2 (Ser250)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O70436, Q15796, Q62432
Gene Symbols:
SMAD2
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser250 of Human Smad2 aa 221-270
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Western Blot
Clone:
SD207-1
Conjugate:
Unconjugated
Gene:
SMAD2
Gene Alias:
7120426M23Rik, EGK_09664, hMAD-2, hSMAD2, JV18, JV18-1, MAD, MAD homolog 2, Mad protein homolog, Madh2, Madr2, Mad-related protein 2, MGC22139, MGC34440, mMad2, mother against DPP homolog 2, mothers against decapentaplegic homolog 2, Mothers against decapentaplegic-like protein 2, mothers against DPP homolog 2, pSMAD2, Sma- and Mad-related protein 2, SMAD, SMAD 2, SMAD family member 2, SMAD, mothers against DPP homolog 2, Smad2, Smad-2, Smad2Deltaexon3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17126, 29357, 4087
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: AP2M1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P84091, P84092, Q96CW1
Gene Symbols: AP2M1
Immunogen: Synthetic peptide within Human AP2M1 aa 351-400
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SD0746
Conjugate: Unconjugated
Gene: AP2M1
Gene Alias: adapter-related protein complex 2 mu subunit, adapter-related protein complex 2 subunit mu, adaptin-mu2, Adaptor protein complex AP-2 subunit mu, adaptor related protein complex 2 mu 1 subunit, adaptor related protein complex 2 subunit mu 1, adaptor related protein complex 2, mu 1 subunit, adaptor-related protein complex 2 subunit mu, adaptor-related protein complex 2, mu 1 subunit, AP-2 complex subunit mu, AP-2 mu 2 chain, AP-2 mu chain, Ap2m1, AP50, Clapm1, clathrin adaptor complex AP2, mu subunit, Clathrin assembly protein complex 2 medium chain, clathrin assembly protein complex 2 mu medium chain, clathrin coat adaptor protein AP50, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP50, clathrin-associated/assembly/adaptor protein, medium 1, coat assembly protein complex 50 kD, HA2 50 kDA subunit, KIAA0109, mu2, Mu2-adaptin, Plasma membrane adaptor AP-2 50 kDa protein, plasma membrane adaptor AP-2 50kDA protein, QtsA-16673, unnamed protein product
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 116563, 1173, 11773
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
AP2M1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P84091, P84092, Q96CW1
Gene Symbols:
AP2M1
Immunogen:
Synthetic peptide within Human AP2M1 aa 351-400
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SD0746
Conjugate:
Unconjugated
Gene:
AP2M1
Gene Alias:
adapter-related protein complex 2 mu subunit, adapter-related protein complex 2 subunit mu, adaptin-mu2, Adaptor protein complex AP-2 subunit mu, adaptor related protein complex 2 mu 1 subunit, adaptor related protein complex 2 subunit mu 1, adaptor related protein complex 2, mu 1 subunit, adaptor-related protein complex 2 subunit mu, adaptor-related protein complex 2, mu 1 subunit, AP-2 complex subunit mu, AP-2 mu 2 chain, AP-2 mu chain, Ap2m1, AP50, Clapm1, clathrin adaptor complex AP2, mu subunit, Clathrin assembly protein complex 2 medium chain, clathrin assembly protein complex 2 mu medium chain, clathrin coat adaptor protein AP50, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP50, clathrin-associated/assembly/adaptor protein, medium 1, coat assembly protein complex 50 kD, HA2 50 kDA subunit, KIAA0109, mu2, Mu2-adaptin, Plasma membrane adaptor AP-2 50 kDa protein, plasma membrane adaptor AP-2 50kDA protein, QtsA-16673, unnamed protein product
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
116563, 1173, 11773
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MKK7
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O14733, Q4KSH7, Q8CE90
Gene Symbols: MAP2K7
Immunogen: Synthetic peptide within Human MEK7 aa 370-419
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SD20-87
Conjugate: Unconjugated
Gene: MAP2K7
Gene Alias: 2, 5930412N11Rik, c-Jun N-terminal kinase kinase 2, Dual specificity mitogen-activated protein kinase kinase 7, EMBL:AAX61178.1}, JN, JNK kinase 2, JNK-activating kinase 2, JNKK, JNKK 2, Jnkk2, MAP kinase kinase 7, MAP2K4, map2k7, map2k7 {ECO:0000312, MAPK/ERK kinase 4, MAPK/ERK kinase 7, MAPKK 4, MAPKK 7, MAPKK7, MEK, MEK 4, MEK 7, Mek7, mitogen activated protein kinase kinase 7, mitogen-activated protein kinase kinase 7, Mkk7, PRKMK7, protein kinase, mitogen activated, kinase 7, SAPK kinase 1, SAPK kinase 4, SAPK/ERK kinase 1, SAPKK1, SAPKK-1, SAPKK4, SAPKK-4, SEK1, sek2, SKK4, Stress-activated protein kinase kinase 4
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 26400, 363855, 5609
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MKK7
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O14733, Q4KSH7, Q8CE90
Gene Symbols:
MAP2K7
Immunogen:
Synthetic peptide within Human MEK7 aa 370-419
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SD20-87
Conjugate:
Unconjugated
Gene:
MAP2K7
Gene Alias:
2, 5930412N11Rik, c-Jun N-terminal kinase kinase 2, Dual specificity mitogen-activated protein kinase kinase 7, EMBL:AAX61178.1}, JN, JNK kinase 2, JNK-activating kinase 2, JNKK, JNKK 2, Jnkk2, MAP kinase kinase 7, MAP2K4, map2k7, map2k7 {ECO:0000312, MAPK/ERK kinase 4, MAPK/ERK kinase 7, MAPKK 4, MAPKK 7, MAPKK7, MEK, MEK 4, MEK 7, Mek7, mitogen activated protein kinase kinase 7, mitogen-activated protein kinase kinase 7, Mkk7, PRKMK7, protein kinase, mitogen activated, kinase 7, SAPK kinase 1, SAPK kinase 4, SAPK/ERK kinase 1, SAPKK1, SAPKK-1, SAPKK4, SAPKK-4, SEK1, sek2, SKK4, Stress-activated protein kinase kinase 4
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
26400, 363855, 5609
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid