PIMA532359
Phospho-SMAD2 (Ser250) Recombinant Rabbit Monoclonal Antibody (SD207-1), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532359-Each-of-1 | In Stock | ₹ 44,619.54 |
PIMA532359 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,619.54
GST (18%): ₹ 8,031.517
Total Price: ₹ 52,651.057
Antigen
Phospho-SMAD2 (Ser250)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O70436, Q15796, Q62432
Gene Symbols
SMAD2
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser250 of Human Smad2 aa 221-270
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Western Blot
Clone
SD207-1
Conjugate
Unconjugated
Gene
SMAD2
Gene Alias
7120426M23Rik, EGK_09664, hMAD-2, hSMAD2, JV18, JV18-1, MAD, MAD homolog 2, Mad protein homolog, Madh2, Madr2, Mad-related protein 2, MGC22139, MGC34440, mMad2, mother against DPP homolog 2, mothers against decapentaplegic homolog 2, Mothers against decapentaplegic-like protein 2, mothers against DPP homolog 2, pSMAD2, Sma- and Mad-related protein 2, SMAD, SMAD 2, SMAD family member 2, SMAD, mothers against DPP homolog 2, Smad2, Smad-2, Smad2Deltaexon3
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
17126, 29357, 4087
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
- SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
- Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
- In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
- The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
- The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
- SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
- Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.
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Antigen: Phospho-SMAD2 (Ser250)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O70436, Q15796, Q62432
Gene Symbols: SMAD2
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser250 of Human Smad2 aa 221-270
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Western Blot
Clone: SD207-1
Conjugate: Unconjugated
Gene: SMAD2
Gene Alias: 7120426M23Rik, EGK_09664, hMAD-2, hSMAD2, JV18, JV18-1, MAD, MAD homolog 2, Mad protein homolog, Madh2, Madr2, Mad-related protein 2, MGC22139, MGC34440, mMad2, mother against DPP homolog 2, mothers against decapentaplegic homolog 2, Mothers against decapentaplegic-like protein 2, mothers against DPP homolog 2, pSMAD2, Sma- and Mad-related protein 2, SMAD, SMAD 2, SMAD family member 2, SMAD, mothers against DPP homolog 2, Smad2, Smad-2, Smad2Deltaexon3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17126, 29357, 4087
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-SMAD2 (Ser250)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O70436, Q15796, Q62432
Gene Symbols:
SMAD2
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser250 of Human Smad2 aa 221-270
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Western Blot
Clone:
SD207-1
Conjugate:
Unconjugated
Gene:
SMAD2
Gene Alias:
7120426M23Rik, EGK_09664, hMAD-2, hSMAD2, JV18, JV18-1, MAD, MAD homolog 2, Mad protein homolog, Madh2, Madr2, Mad-related protein 2, MGC22139, MGC34440, mMad2, mother against DPP homolog 2, mothers against decapentaplegic homolog 2, Mothers against decapentaplegic-like protein 2, mothers against DPP homolog 2, pSMAD2, Sma- and Mad-related protein 2, SMAD, SMAD 2, SMAD family member 2, SMAD, mothers against DPP homolog 2, Smad2, Smad-2, Smad2Deltaexon3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17126, 29357, 4087
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: AP2M1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P84091, P84092, Q96CW1
Gene Symbols: AP2M1
Immunogen: Synthetic peptide within Human AP2M1 aa 351-400
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SD0746
Conjugate: Unconjugated
Gene: AP2M1
Gene Alias: adapter-related protein complex 2 mu subunit, adapter-related protein complex 2 subunit mu, adaptin-mu2, Adaptor protein complex AP-2 subunit mu, adaptor related protein complex 2 mu 1 subunit, adaptor related protein complex 2 subunit mu 1, adaptor related protein complex 2, mu 1 subunit, adaptor-related protein complex 2 subunit mu, adaptor-related protein complex 2, mu 1 subunit, AP-2 complex subunit mu, AP-2 mu 2 chain, AP-2 mu chain, Ap2m1, AP50, Clapm1, clathrin adaptor complex AP2, mu subunit, Clathrin assembly protein complex 2 medium chain, clathrin assembly protein complex 2 mu medium chain, clathrin coat adaptor protein AP50, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP50, clathrin-associated/assembly/adaptor protein, medium 1, coat assembly protein complex 50 kD, HA2 50 kDA subunit, KIAA0109, mu2, Mu2-adaptin, Plasma membrane adaptor AP-2 50 kDa protein, plasma membrane adaptor AP-2 50kDA protein, QtsA-16673, unnamed protein product
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 116563, 1173, 11773
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
AP2M1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P84091, P84092, Q96CW1
Gene Symbols:
AP2M1
Immunogen:
Synthetic peptide within Human AP2M1 aa 351-400
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SD0746
Conjugate:
Unconjugated
Gene:
AP2M1
Gene Alias:
adapter-related protein complex 2 mu subunit, adapter-related protein complex 2 subunit mu, adaptin-mu2, Adaptor protein complex AP-2 subunit mu, adaptor related protein complex 2 mu 1 subunit, adaptor related protein complex 2 subunit mu 1, adaptor related protein complex 2, mu 1 subunit, adaptor-related protein complex 2 subunit mu, adaptor-related protein complex 2, mu 1 subunit, AP-2 complex subunit mu, AP-2 mu 2 chain, AP-2 mu chain, Ap2m1, AP50, Clapm1, clathrin adaptor complex AP2, mu subunit, Clathrin assembly protein complex 2 medium chain, clathrin assembly protein complex 2 mu medium chain, clathrin coat adaptor protein AP50, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP50, clathrin-associated/assembly/adaptor protein, medium 1, coat assembly protein complex 50 kD, HA2 50 kDA subunit, KIAA0109, mu2, Mu2-adaptin, Plasma membrane adaptor AP-2 50 kDa protein, plasma membrane adaptor AP-2 50kDA protein, QtsA-16673, unnamed protein product
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
116563, 1173, 11773
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MKK7
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O14733, Q4KSH7, Q8CE90
Gene Symbols: MAP2K7
Immunogen: Synthetic peptide within Human MEK7 aa 370-419
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SD20-87
Conjugate: Unconjugated
Gene: MAP2K7
Gene Alias: 2, 5930412N11Rik, c-Jun N-terminal kinase kinase 2, Dual specificity mitogen-activated protein kinase kinase 7, EMBL:AAX61178.1}, JN, JNK kinase 2, JNK-activating kinase 2, JNKK, JNKK 2, Jnkk2, MAP kinase kinase 7, MAP2K4, map2k7, map2k7 {ECO:0000312, MAPK/ERK kinase 4, MAPK/ERK kinase 7, MAPKK 4, MAPKK 7, MAPKK7, MEK, MEK 4, MEK 7, Mek7, mitogen activated protein kinase kinase 7, mitogen-activated protein kinase kinase 7, Mkk7, PRKMK7, protein kinase, mitogen activated, kinase 7, SAPK kinase 1, SAPK kinase 4, SAPK/ERK kinase 1, SAPKK1, SAPKK-1, SAPKK4, SAPKK-4, SEK1, sek2, SKK4, Stress-activated protein kinase kinase 4
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 26400, 363855, 5609
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MKK7
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O14733, Q4KSH7, Q8CE90
Gene Symbols:
MAP2K7
Immunogen:
Synthetic peptide within Human MEK7 aa 370-419
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SD20-87
Conjugate:
Unconjugated
Gene:
MAP2K7
Gene Alias:
2, 5930412N11Rik, c-Jun N-terminal kinase kinase 2, Dual specificity mitogen-activated protein kinase kinase 7, EMBL:AAX61178.1}, JN, JNK kinase 2, JNK-activating kinase 2, JNKK, JNKK 2, Jnkk2, MAP kinase kinase 7, MAP2K4, map2k7, map2k7 {ECO:0000312, MAPK/ERK kinase 4, MAPK/ERK kinase 7, MAPKK 4, MAPKK 7, MAPKK7, MEK, MEK 4, MEK 7, Mek7, mitogen activated protein kinase kinase 7, mitogen-activated protein kinase kinase 7, Mkk7, PRKMK7, protein kinase, mitogen activated, kinase 7, SAPK kinase 1, SAPK kinase 4, SAPK/ERK kinase 1, SAPKK1, SAPKK-1, SAPKK4, SAPKK-4, SEK1, sek2, SKK4, Stress-activated protein kinase kinase 4
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
26400, 363855, 5609
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: IRF6
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O14896, P97431
Gene Symbols: Irf6
Immunogen: Recombinant protein Human IRF6 aa 364-467
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SD202-6
Conjugate: Unconjugated
Gene: Irf6
Gene Alias: AI876454, E230028I05Rik, interferon regulatory factor 6, IRF6, IRF-6, irf6 protein, IRF-6, transcription factor, LPS, mirf6, OFC6, PIT, PPS, PPS1, transcriptional factor, VWS, VWS1, zgc:63500
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 364081, 3664, 54139
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IRF6
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O14896, P97431
Gene Symbols:
Irf6
Immunogen:
Recombinant protein Human IRF6 aa 364-467
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SD202-6
Conjugate:
Unconjugated
Gene:
Irf6
Gene Alias:
AI876454, E230028I05Rik, interferon regulatory factor 6, IRF6, IRF-6, irf6 protein, IRF-6, transcription factor, LPS, mirf6, OFC6, PIT, PPS, PPS1, transcriptional factor, VWS, VWS1, zgc:63500
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
364081, 3664, 54139
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid