PIMA532220

CHK2 Recombinant Rabbit Monoclonal Antibody (SC604), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532220-Each-of-1 In Stock ₹ 45,646.26

PIMA532220 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

CHK2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

O96017

Gene Symbols

Chek2

Immunogen

Recombinant protein within Human Chk2 aa 10-200

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SC604

Conjugate

Unconjugated

Gene

Chek2

Gene Alias

CDS1, cds1 homolog, Checkpoint kinase 2, Checkpoint like protein CHK2, checkpoint-like protein CHK2, Chek2, Chk2, Chk2 (phospho T68), Chk2 (pThr68), CHK2 checkpoint homolog, CHK2 checkpoint homolog (S. pombe), Chk2 phospho, Chk2 phospho T68, del9, EC 2.7.11.1, hCds1, HuCds 1, HuCds1, kinase Chk2, LFS2, OTTHUMP00000199044, OTTHUMP00000199045, OTTHUMP00000199064, OTTHUMP00000199115, OTTHUMP00000199116, phospho Chk2 (T68), phospho Thr68 Chk2, PP1425, protein kinase Chk2, Rad53, Rad53 homolog, RP11-436C9.1, Serine/threonine protein kinase Chk2, serine/threonine-protein kinase Chk2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

11200

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • CHEK2 (CHK2) is a serine/threonine kinase and a component of the DNA damage checkpoint pathway
  • A mutation in CHK2 has been linked to cancer
  • CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in CHK2 are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

Compare Similar Items

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Thermo Scientific

PIMA532220

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Antigen:
CHK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O96017

Gene Symbols:
Chek2

Immunogen:
Recombinant protein within Human Chk2 aa 10-200

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC604

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1, cds1 homolog, Checkpoint kinase 2, Checkpoint like protein CHK2, checkpoint-like protein CHK2, Chek2, Chk2, Chk2 (phospho T68), Chk2 (pThr68), CHK2 checkpoint homolog, CHK2 checkpoint homolog (S. pombe), Chk2 phospho, Chk2 phospho T68, del9, EC 2.7.11.1, hCds1, HuCds 1, HuCds1, kinase Chk2, LFS2, OTTHUMP00000199044, OTTHUMP00000199045, OTTHUMP00000199064, OTTHUMP00000199115, OTTHUMP00000199116, phospho Chk2 (T68), phospho Thr68 Chk2, PP1425, protein kinase Chk2, Rad53, Rad53 homolog, RP11-436C9.1, Serine/threonine protein kinase Chk2, serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11200

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

PIMA532222

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Antigen:
PRP19

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q99KP6, Q9JMJ4, Q9UMS4

Gene Symbols:
Prpf19

Immunogen:
recombinant protein within Human PRP19 aa 380-524

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC06-53

Conjugate:
Unconjugated

Gene:
Prpf19

Gene Alias:
AA617263, AL024362, D19Wsu55e, hPSO4, Neuronal differentiation-related gene protein, NMP200, Nuclear matrix protein 200, nuclear matrix protein NMP200 related to splicing factor PRP19, nuclear matrix protein SNEV, pre-mRNA processing factor 19, pre-mRNA-processing factor 19, PRP19, prp19 beta, PRP19/PSO4 homolog, PRP19/PSO4 pre-mRNA processing factor 19 homolog, PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae), PRPF19, PSO4, psoralen 4, RING-type E3 ubiquitin transferase PRP19, Senescence evasion factor, SNEV, UBOX4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
246216, 27339, 28000

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

PIMA532223

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Antigen:
Phospho-SMC1 (Ser957)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q14683, Q8NDV3

Gene Symbols:
SMC1A, SMC1B

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser957 of Human SMC1 aa 945-980

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC65-03

Conjugate:
Unconjugated

Gene:
SMC1A

Gene Alias:
14S cohesin SMC1 subunit, 5830426I24Rik, CDLS2, chromosome segregation protein SmcB, DKFZp686L19178, DXhXs423e, DXS423E, KIAA0178, MGC138332, mitosis-specific chromosome segregation protein like protein beta, mKIAA0178, RP6-29D12.1, Sb1.8, segregation of mitotic chromosomes 1, segregation of mitotic chromosomes b, segregation of mitotic chromosomes-like 1, SM1A, SMC, SMC (segregation of mitotic chromosomes 1)-like 1, SMC protein, SMC protein 1A, SMC protein 1B, SMC1, SMC1 (structural maintenance of chromosomes 1, yeast)-like 1, SMC1 protein, SMC1 protein cohesin subunit, SMC1 structural maintenance of chromosomes 1-like 1, SMC1 structural maintenance of chromosomes 1-like 2, Smc1a, SMC-1A, smc1a.L, smc1aa, Smc1alpha, SMC-1-alpha, SMC1alpha protein, Smc1b, SMC-1B, SMC1BETA, SMC-1-beta, SMC1L1, Smc1l2, Smcb, SMC-like 1, SMC-protein, structural maintenace of chromosomes 1B, structural maintenance of chromosomes 1, structural maintenance of chromosomes 1 like 1, structural maintenance of c

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
27127, 8243

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532224

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Antigen:
Myoglobin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P02144, P04247, Q9QZ76

Gene Symbols:
MB

Immunogen:
Synthetic peptide within Human Myoglobin aa 121-154

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC06-38

Conjugate:
Unconjugated

Gene:
MB

Gene Alias:
AI325109, Human myoglobin, Mb, MGC13548, myoglobgin, myoglobin, OTTHUMP00000197936, PVALB

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17189, 4151, 59108

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid