PIMA532139

M-CSF Recombinant Rabbit Monoclonal Antibody (SU0413), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532139-Each-of-1 In Stock ₹ 44,619.54

PIMA532139 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

M-CSF

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P09603

Gene Symbols

Csf1

Immunogen

Synthetic peptide within Human MCSF aa 56-105

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

SU0413

Conjugate

Unconjugated

Gene

Csf1

Gene Alias

C87615, colony stimulating factor 1, colony stimulating factor 1 (macrophage), colony-stimulating factor-1 splice variant, CSF1, CSF-1, Csfm, H-MCSF, lanimostim, macrophage colony stimulating factor 1, macrophage colony stimulating factor alpha, macrophage colony stimulating factor beta, macrophage colony-stimulating factor, macrophage colony-stimulating factor 1, macrophage colony-stimulating factor beta, macrophage-colony stimulating factor alpha, MCSF, MCSF alpha, MCSFBETA, MGC31930, M-MCSF, op, osteopetrosis, Processed macrophage colony-stimulating factor 1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1435

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • M-CSF (Macrophage colony-stimulating factor, CSF-1) is a survival factor essential for the proliferation and development of monocytes, macrophages, and osteoclast progenitor cells
  • M-CSF also induces VEGF (vascular endothelial growth factor) secretion by macrophages, thereby mediating mobilization of endothelial progenitor cells and neovascularization
  • M-CSF is present as several bioactive isoforms that differ in potency and stability
  • The full-length protein is synthesized as a membrane-spanning protein that can be expressed on the cell surface or further cleaved and modified in the secretory vesicle
  • Further, M-CSF is a disulfide-bonded homodimer which is processed into one of two isoforms, a glycoprotein or a proteoglycan that has been modified by the addition of chondroitin sulfate to each subunit
  • Binding of M-CSF to its receptor, c-Fms (CSF-1R or CD115) induces dimerization of the receptor followed by internalization and degradation of the complex
  • Functionally, M-CSF is known to stimulate differentiation of hematopoietic stem cells to monocyte-macrophage cell populations in culture
  • M-CSF acts through the CSF receptor 1
  • Although human M-CSF shows activity on mouse cells, mouse CSF shows no activity on human cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532139

--


Antigen:
M-CSF

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P09603

Gene Symbols:
Csf1

Immunogen:
Synthetic peptide within Human MCSF aa 56-105

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
SU0413

Conjugate:
Unconjugated

Gene:
Csf1

Gene Alias:
C87615, colony stimulating factor 1, colony stimulating factor 1 (macrophage), colony-stimulating factor-1 splice variant, CSF1, CSF-1, Csfm, H-MCSF, lanimostim, macrophage colony stimulating factor 1, macrophage colony stimulating factor alpha, macrophage colony stimulating factor beta, macrophage colony-stimulating factor, macrophage colony-stimulating factor 1, macrophage colony-stimulating factor beta, macrophage-colony stimulating factor alpha, MCSF, MCSF alpha, MCSFBETA, MGC31930, M-MCSF, op, osteopetrosis, Processed macrophage colony-stimulating factor 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1435

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532140

--


Antigen:
SOX18

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P35713, P43680

Gene Symbols:
SOX18

Immunogen:
Recombinant protein within Human SOX18 aa 250-384

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ST43-02

Conjugate:
Unconjugated

Gene:
SOX18

Gene Alias:
AI385749, HLTRS, HLTS, Ra, ragged, Ragl, SOX18, Sox-18, SRY (sex determining region Y)-box 18, SRY box 18, SRY-box 18, SRY-box containing gene 18, SRY-box transcription factor 18, Sry-related HMG-box gene 18, transcription factor SOX-18

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20672, 311723, 54345

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532141

--


Antigen:
Phospho-p53 (Thr55)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P04637

Gene Symbols:
Tp53

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Thr55 of Human p53 aa 31-80

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ST0439

Conjugate:
Unconjugated

Gene:
Tp53

Gene Alias:
Antigen NY-CO-13, bbl, BCC7, bfy, bhy, cellular tumor antigen p53, Cys 51 Stop, EGK_08142, FLJ92943, HGNC11998, I79_002739, LFS1, Li-Fraumeni syndrome, mutant p53, mutant tumor protein 53, OTTMUSP00000006194, p44, p53, p53 cellular tumor antigen, p53 protein, p53 tumor suppressor, p53 tumor suppressor phosphoprotein, phosphoprotein p53, Tp53, tp53.L, transformation related protein 53, transformation-related protein 53, Trp248, Trp53, tumor protein 53, tumor protein p53, tumor protein p53 (Li-Fraumeni syndrome), tumor protein p53 L homeolog, tumor suppressor p53, tumor suppressor p53 phosphoprotein, tumor suppressor protein p53, tumor supressor p53, Tumour Protein p53, XELAEV_180196761mg, Xp53, Xrel3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532142

--


Antigen:
Phospho-p53 (Ser376)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P04637

Gene Symbols:
Tp53

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser376 of Human p53 aa 344-393

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ST0440

Conjugate:
Unconjugated

Gene:
Tp53

Gene Alias:
Antigen NY-CO-13, bbl, BCC7, bfy, bhy, cellular tumor antigen p53, Cys 51 Stop, EGK_08142, FLJ92943, HGNC11998, I79_002739, LFS1, Li-Fraumeni syndrome, mutant p53, mutant tumor protein 53, OTTMUSP00000006194, p44, p53, p53 cellular tumor antigen, p53 protein, p53 tumor suppressor, p53 tumor suppressor phosphoprotein, phosphoprotein p53, Tp53, tp53.L, transformation related protein 53, transformation-related protein 53, Trp248, Trp53, tumor protein 53, tumor protein p53, tumor protein p53 (Li-Fraumeni syndrome), tumor protein p53 L homeolog, tumor suppressor p53, tumor suppressor p53 phosphoprotein, tumor suppressor protein p53, tumor supressor p53, Tumour Protein p53, XELAEV_180196761mg, Xp53, Xrel3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid