PIMA532105

Phospho-HSF1 (Ser326) Recombinant Rabbit Monoclonal Antibody (SU31-03), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532105-Each-of-1 In Stock ₹ 44,619.54

PIMA532105 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

Phospho-HSF1 (Ser326)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q00613

Gene Symbols

Hsf1

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Ser326 of Human HSF1 aa 301-350

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SU31-03

Conjugate

Unconjugated

Gene

Hsf1

Gene Alias

AA960185, heat shock factor 1, heat shock factor 2, Heat shock factor protein 1, Heat shock transcription factor 1, heat shock transcription factor 1 alpha isoform, heat shock transcription factor 1 beta isoform, heat shock transcription factor 1 gammaalpha isoform, heat shock transcription factor 1 gammabeta isoform, HSF, HSF 1, Hsf1, Hsf1alpha, Hsf1beta, Hsf1gammaalpha, Hsf1gammabeta, HSTF 1, HSTF1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3297

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA533167

--

Img

Thermo Scientific

PIMA532497

--

Img

Thermo Scientific

PIMA532295

--

Img

Thermo Scientific

PIMA531982

--

Img

Thermo Scientific

PIMA531996

--

Img

Thermo Scientific

PIMA532444

--

Img

Thermo Scientific

PIMA532258

--

Img

Thermo Scientific

PIMA532101

--

Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • All organisms respond to elevated temperatures and a variety of environmental stresses by rapid synthesis of heat shock RNAs and proteins
  • The regulation of heat shock gene transcription is mediated by the transcriptional activator, heat shock factor (HSF), which binds to heat shock response elements (HSEs)
  • These HSEs are found as three repeats of a 5-nucleotide {nGAAn} module, arranged in alternating orientation and present upstream of all heat shock genes
  • The HSEs are highly conserved among species yet HSF purified from yeast, Drosophila and human have different molecular weights and the proteins do not show significant immunological cross reaction
  • Two HSFs have been identified in human cells, HSF1 and HSF2, which bind to the same HSEs and have 38% sequence identity
  • These factors are activated by distinct stimuli, HSF1 is responsive to classical stress signals such as heat, heavy metals and oxidative reagents, whereas HSF2 is activated during hemin-mediated differentiation of human erythroleukemia cells
  • HSF1 exists constitutively in the cytoplasm and the nucleus of unstressed cells as a monomer which lacks DNA binding activity
  • Through an unknown signal generated during stress, HSF1 becomes activated to a nuclear localized, trimeric state which binds to DNA
  • The phosphorylation of HSF1 is necessary for maximal transcription of heat shock genes.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532105

--


Antigen:
Phospho-HSF1 (Ser326)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q00613

Gene Symbols:
Hsf1

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser326 of Human HSF1 aa 301-350

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SU31-03

Conjugate:
Unconjugated

Gene:
Hsf1

Gene Alias:
AA960185, heat shock factor 1, heat shock factor 2, Heat shock factor protein 1, Heat shock transcription factor 1, heat shock transcription factor 1 alpha isoform, heat shock transcription factor 1 beta isoform, heat shock transcription factor 1 gammaalpha isoform, heat shock transcription factor 1 gammabeta isoform, HSF, HSF 1, Hsf1, Hsf1alpha, Hsf1beta, Hsf1gammaalpha, Hsf1gammabeta, HSTF 1, HSTF1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3297

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532106

--


Antigen:
PKC alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P05696, P17252, P20444

Gene Symbols:
PRKCA

Immunogen:
Recombinant protein within Human PKC alpha aa 560-672

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot, Western Blot

Clone:
SU31-08

Conjugate:
Unconjugated

Gene:
PRKCA

Gene Alias:
AAG6, aging-associated gene 6, AI875142, EC 2.7.11.13, FHC, FTH, FTHL6, im:7139045, kinase PKC-alpha, KPCA, MGC104426, PIG15, PKC III, Pkca, PKC-A, PKC-alpha, PKC-III, PKRCA, PLIF, PRKACA, Prkca, prkcaa, protein kinase C, protein kinase C alpha, protein kinase C alpha type, protein kinase C alpha type, protein kinase C, alpha, a, protein kinase C, alpha, protein kinase C, alpha, a, protein kinase c-alpha, si:dkey-8l19.1, Unknown (protein for IMAGE:7139045), unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18750, 24680, 5578

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532107

--


Antigen:
Caldesmon

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q05682, Q62736

Gene Symbols:
Cald1

Immunogen:
Synthetic peptide within Human Caldesmon aa 744-793

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SU03-19

Conjugate:
Unconjugated

Gene:
Cald1

Gene Alias:
4833423D12Rik, AI195384, AV071549, AW536160, C920027I18Rik, CAD, Cald1, Caldesmon, caldesmon 1, CDM, HCAD, H-CAD, h-caldesmon, LCAD, L-CAD, L-caldesmon, MGC21352, NAG22, Non-muscle caldesmon, OTTHUMP00000207950, OTTHUMP00000207953, OTTHUMP00000207954, OTTHUMP00000207955, OTTHUMP00000214473, smooth muscle caldesmon, testis secretory sperm-binding protein Li 227n

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
109624, 25687, 800

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532108

--


Antigen:
LGR5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
D4AC13, O75473, Q9Z1P4

Gene Symbols:
Lgr5

Immunogen:
Synthetic peptide within Human LGR5 aa 816-865

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
SU32-04

Conjugate:
Unconjugated

Gene:
Lgr5

Gene Alias:
Fex, follicle expressed hormone, G protein-coupled receptor 49, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, GRP49, HG38, leucine rich repeat containing G protein coupled receptor 5, leucine rich repeat containing G protein-coupled receptor 5, leucine-rich repeat containing G protein-coupled receptor 5, leucine-rich repeat-containing G protein-coupled receptor 5, leucine-rich repeat-containing G-protein coupled receptor 5, Lgr5, orphan G protein-coupled receptor HG38, orphan G-protein coupled receptor FEX

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14160, 299802, 8549

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid