PIMA532108

LGR5 Recombinant Rabbit Monoclonal Antibody (SU32-04), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532108-Each-of-1 In Stock ₹ 46,245.18

PIMA532108 - Each of 1

₹ 46,245.18

In Stock

Quantity

1

Base Price: ₹ 46,245.18

GST (18%): ₹ 8,324.132

Total Price: ₹ 54,569.312

Antigen

LGR5

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

D4AC13, O75473, Q9Z1P4

Gene Symbols

Lgr5

Immunogen

Synthetic peptide within Human LGR5 aa 816-865

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Western Blot

Clone

SU32-04

Conjugate

Unconjugated

Gene

Lgr5

Gene Alias

Fex, follicle expressed hormone, G protein-coupled receptor 49, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, GRP49, HG38, leucine rich repeat containing G protein coupled receptor 5, leucine rich repeat containing G protein-coupled receptor 5, leucine-rich repeat containing G protein-coupled receptor 5, leucine-rich repeat-containing G protein-coupled receptor 5, leucine-rich repeat-containing G-protein coupled receptor 5, Lgr5, orphan G protein-coupled receptor HG38, orphan G-protein coupled receptor FEX

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

14160, 299802, 8549

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • G protein-coupled receptor GPR49 has been reported to be expressed in brain, skeletal muscle, placenta, and spinal cord
  • ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries and from human germ cell, uterus, and brain libraries
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This &quoteturn-off&quote activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532108

--


Antigen:
LGR5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
D4AC13, O75473, Q9Z1P4

Gene Symbols:
Lgr5

Immunogen:
Synthetic peptide within Human LGR5 aa 816-865

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
SU32-04

Conjugate:
Unconjugated

Gene:
Lgr5

Gene Alias:
Fex, follicle expressed hormone, G protein-coupled receptor 49, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, GRP49, HG38, leucine rich repeat containing G protein coupled receptor 5, leucine rich repeat containing G protein-coupled receptor 5, leucine-rich repeat containing G protein-coupled receptor 5, leucine-rich repeat-containing G protein-coupled receptor 5, leucine-rich repeat-containing G-protein coupled receptor 5, Lgr5, orphan G protein-coupled receptor HG38, orphan G-protein coupled receptor FEX

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14160, 299802, 8549

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532109

--


Antigen:
ELK1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
A4GTP4, P19419, P41969

Gene Symbols:
ELK1

Immunogen:
Synthetic peptide within Human ELK1 aa 378-428

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
SU32-05

Conjugate:
Unconjugated

Gene:
ELK1

Gene Alias:
ELK 1, ELK1, Elk-1, ELK1, ETS transcription factor, ELK1, member of ETS oncogene family, ETS domain-containing protein Elk-1, ETS transcription factor ELK1, ETS-like gene 1, Oncogene Elk1, tyrosine kinase (ELK1) oncogene

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13712, 2002, 314436

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532111

--


Antigen:
BAK

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q16611

Gene Symbols:
BAK1

Immunogen:
Synthetic peptide within Human Bak aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SU32-07

Conjugate:
Unconjugated

Gene:
BAK1

Gene Alias:
Apoptosis regulator BAK, BAK, Bak1, BAK-LIKE, BCL2 antagonist/killer 1, Bcl2 homologous antagonist/killer, Bcl-2 homologous antagonist/killer, BCL2-antagonist/killer 1, BCL2L7, bcl2-L-7, BCL2-like 7 protein, BCL2-like 7protein, bcl-2-like protein 7, Bcl-2-likeous antagonist/killer, CDN1, MGC117255, MGC3887, N-Bak, N-BAK1, pro-apoptotic protein BAK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
578

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532113

--


Antigen:
DARPP-32

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q60829, Q6J4I0, Q9UD71

Gene Symbols:
Ppp1r1b

Immunogen:
Recombinant protein within Human DARPP32 aa 1-94

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Immunohistochemistry, Western Blot

Clone:
SU0329

Conjugate:
Unconjugated

Gene:
Ppp1r1b

Gene Alias:
AU040756, DARPP32, DARPP-32, dopamine- and cAMP-regulated neuronal phosphoprotein, dopamine and cAMP-regulated neuronal phosphoprotein 32, dopamine- and cAMP-regulated phosphoprotein DARPP-32, FLJ20940, IPPD, neuronal phosphoprotein DARPP-32, OTTHUMP00000164275, OTTHUMP00000164276, Ppp1r1b, PPR1B, protein pho, protein phosphatase 1 regulatory inhibitor subunit 1B, protein phosphatase 1 regulatory subunit 1B, protein phosphatase 1, regulatory (inhibitor) subunit 1B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19049, 360616, 84152

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid