PA1711

VDR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1711-Each-of-1 In Stock ₹ 44,191.74

PA1711 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

VDR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

VDR

Gene Alias

1,25-dihydroxyvitamin D3 receptor; HGNC:12679; I79_025795; Nr1i1; Nuclear receptor subfamily 1 group I member 1; PPP1R163; protein phosphatase 1, regulatory subunit 163; vdr; vdr.S; vdr-A; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D (1,25- dihydroxyvitamin D3) receptor S homeolog; vitamin D (1,25-dihydroxyvitamin D3) receptor; vitamin D nuclear receptor variant 1; vitamin D receptor; vitamin D receptor protein; vitamin D receptor S homeolog; Vitamin D3 receptor; XELAEV_18015993mg; xVDR

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Chicken, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Gel Shift, Immunoprecipitation, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 0.05% sodium azide

Gene Accession No.

O42392, P11473, P13053, P48281

Gene Symbols

VDR

Immunogen

Synthetic Peptide: E(395) E H S K Q Y R C L S F Q P E C S M K(413)

Regulatory Status

RUO

Gene ID (Entrez)

22337, 24873, 395988, 7421

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • PA1-711 detects vitamin D receptor (VDR) from human, mouse and rat tissues
  • PA1-711 has been successfully used in Western blot, immunoprecipitation and gel shift procedures
  • By Western blot, this antibody detects an ∽53 kDa protein representing VDR in COS-7 cells transfected with the human gene
  • PA1-711 supershifts DNA fragments that contain VDR response elements (e.g., rat osteocalcin and mouse osteopontin upstream elements)
  • PA1-711 immunizing peptide corresponds to amino acid residues 395-413 from human VDR
  • Recombinant human VDR (Cat
  • # RP-710) and human RXR beta (catalog # RP-812) proteins can be purchased separately for control experiments in Western blot, immunoprecipitation and gel shift procedures
  • Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone
  • The 1,25-dihydroxy-vitamin D3 receptor (VDR) belongs to the superfamily of steroid hormone receptors which includes estrogen, progesterone, glucocorticoid, androgen, and thyroid hormone receptors
  • Vitamin D modulates calcium and phosphorus homeostasis, bone remodeling, cell growth regulation, and differentiation
  • Studies have found VDR in the intestine, bone, kidney, epidermis, and cells of the endocrine immune system
  • Repression of T-cell proliferation and interleukin-2 (IL-2) gene expression, for example, occurs when VDR binds within the IL-2 enhancer
  • Formation of VDR/retinoic X receptor (RXR) heterodimers in the presence of intracellular 1,25(OH)2D3 has been shown to interfere with assembly of nuclear factor of activated T-cells (NFATp)/Fos/Jun/DNA complex and subsequent IL-2 gene transcription
  • The corresponding gene for the vitamin D receptor is NR1I1.

Compare Similar Items

Show Difference

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Thermo Scientific

PA1711

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Antigen:
VDR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VDR

Gene Alias:
1,25-dihydroxyvitamin D3 receptor; HGNC:12679; I79_025795; Nr1i1; Nuclear receptor subfamily 1 group I member 1; PPP1R163; protein phosphatase 1, regulatory subunit 163; vdr; vdr.S; vdr-A; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D (1,25- dihydroxyvitamin D3) receptor S homeolog; vitamin D (1,25-dihydroxyvitamin D3) receptor; vitamin D nuclear receptor variant 1; vitamin D receptor; vitamin D receptor protein; vitamin D receptor S homeolog; Vitamin D3 receptor; XELAEV_18015993mg; xVDR

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Gel Shift, Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
O42392, P11473, P13053, P48281

Gene Symbols:
VDR

Immunogen:
Synthetic Peptide: E(395) E H S K Q Y R C L S F Q P E C S M K(413)

Regulatory Status:
RUO

Gene ID (Entrez):
22337, 24873, 395988, 7421

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PA17201

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Antigen:
Adenovirus

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Adeno Virus; AdV; HADV

Host Species:
Goat

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry

Concentration:
4-5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Gradient purified, disrupted Adenovirus type 5 virions.

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PA17205

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Antigen:
Campylobacter jejuni

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
C. jejuni

Host Species:
Rabbit

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Concentration:
4-5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Campylobacter jejuni whole cells

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PA172055

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Antigen:
Human Serum Albumin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALB

Gene Alias:
Alb; Alb1; Alb-1; albumin; albumin (32 AA); albumin (AA 34); albumin 1; Albza; ANALBA; cell growth inhibiting protein 42; DKFZp779N1935; FDAH; GIG20; GIG42; growth-inhibiting protein 20; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619; PRO2675; Serum albumin; UNQ696/PRO1341

Host Species:
Chicken

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgY

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.075% sodium azide; pH 7.2

Gene Accession No.:
P02768

Gene Symbols:
ALB

Immunogen:
Purified normal human serum albumin.

Regulatory Status:
RUO

Gene ID (Entrez):
213

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid