PA186558
Phospho-NMDAR2B (Tyr1472) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA186558-Each-of-1 | In Stock | ₹ 50,223.72 |
PA186558 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,223.72
GST (18%): ₹ 9,040.27
Total Price: ₹ 59,263.99
Antigen
Phospho-NMDAR2B (Tyr1472)
Classification
Polyclonal
Formulation
0.01M HEPES with 0.01% BSA, 50% glycerol and 0.09% sodium azide; pH 7.5
Gene Accession No.
Q00960
Gene Symbols
GRIN2B
Immunogen
Synthetic phosphopeptide corresponding to an amino acid sequence within the NR2B subunit of the NMDA receptor, which includes phosphorylated Tyr1472.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
GRIN2B
Gene Alias
AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
24410
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- PA1-86558 specifically recognizes the 180 kDa NR2B subunit of the NMDA (N-methyl-D-aspartate) receptor when phosphorylated at Tyr1472
- Predicted to react with bovine, chicken, dog, human, monkey, mouse and zebrafish based on sequence homology
- For the detection of phosphoproteins, tyrosine phosphatase inhibitors such as 1mM sodium orthovanadate should be added to the sample buffer
- Milk or other casein-based blocking solutions are not recommended as casein is a phosphoprotein and its use can result in high background
- In Western blot, this antibody detects a band at ∽180 kDa in rat brain hippocampal lysate
- In Western blot, this antibody also labels proteins of 65kDa and 115kDa
- NMDAR2B is a member of the N-methyl-D-aspartate (NMDA) class of ionotropic glutamate receptors
- NMDA receptors (NMDAR) have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning
- NMDAR play a role in neuronal development and has been implicated in several disorders of the central nervous system including Alzheimer’s Disease, epilepsy and ischemic neuronal cell death
- Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression
- Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity
- NMDR2B is a heterotrimer comprised of seven enetically encoded and differentially expressed subunits that include NR1, NR2 and NR3
- Diseases associated with the dysfunction of NMDAR2B include epileptic encephalopathy, autosomal dominant 6-related mental retardation.
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Antigen: Phospho-NMDAR2B (Tyr1472)
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.01% BSA, 50% glycerol and 0.09% sodium azide; pH 7.5
Gene Accession No.: Q00960
Gene Symbols: GRIN2B
Immunogen: Synthetic phosphopeptide corresponding to an amino acid sequence within the NR2B subunit of the NMDA receptor, which includes phosphorylated Tyr1472.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: GRIN2B
Gene Alias: AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 24410
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-NMDAR2B (Tyr1472)
Classification:
Polyclonal
Formulation:
0.01M HEPES with 0.01% BSA, 50% glycerol and 0.09% sodium azide; pH 7.5
Gene Accession No.:
Q00960
Gene Symbols:
GRIN2B
Immunogen:
Synthetic phosphopeptide corresponding to an amino acid sequence within the NR2B subunit of the NMDA receptor, which includes phosphorylated Tyr1472.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
GRIN2B
Gene Alias:
AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
24410
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: alpha/beta Tubulin
Classification: Polyclonal
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: A2AQ07, P02550, P07437, P68369, P68370, Q71U36, Q767L7, Q9H4B7
Gene Symbols: TUBA1A, TUBB, TUBB1
Immunogen: Purified porcine brain tubulin.
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine, Rat
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Gene: TUBB1
Gene Alias: 2810484G07Rik; Alpha-tubulin 1; Alpha-tubulin 3; Alpha-tubulin isotype M-alpha-1; B-ALPHA-1; beta 5-tubulin; beta Ib tubulin; CDCBM6; CSCSC1; Detyrosinated tubulin alpha-1A chain; FLJ30169; H2 ALPHA; hum-a-tub1; hum-a-tub2; LIS3; M(beta)1; M40; OK/SW-cl.56; Talpha1 alpha-tubulin; Tuba1; Tuba-1; TUBA1A; TUBA3; TUBB; TUBB1; TUBB2A; TUBB5; Tubulin alpha; tubulin alpha 1a; tubulin alpha 3; tubulin alpha-1 chain; Tubulin alpha-1A chain; tubulin alpha-3 chain; Tubulin B-alpha-1; tubulin beta; tubulin beta 1 class VI; tubulin beta chain; tubulin beta class I; tubulin beta-1 chain; Tubulin beta-5 chain; tubulin, alpha 1; tubulin, alpha 1A; tubulin, alpha, brain-specific; tubulin, beta 1 class VI; tubulin, beta 2A class IIa; tubulin, beta class I; tubulin, beta family 1; tubulin, beta polypeptide; a/β-tubulin
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100134983, 100135051, 203068, 22142, 545486, 64158, 679312, 733686, 7846, 81027
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
alpha/beta Tubulin
Classification:
Polyclonal
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
A2AQ07, P02550, P07437, P68369, P68370, Q71U36, Q767L7, Q9H4B7
Gene Symbols:
TUBA1A, TUBB, TUBB1
Immunogen:
Purified porcine brain tubulin.
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Gene:
TUBB1
Gene Alias:
2810484G07Rik; Alpha-tubulin 1; Alpha-tubulin 3; Alpha-tubulin isotype M-alpha-1; B-ALPHA-1; beta 5-tubulin; beta Ib tubulin; CDCBM6; CSCSC1; Detyrosinated tubulin alpha-1A chain; FLJ30169; H2 ALPHA; hum-a-tub1; hum-a-tub2; LIS3; M(beta)1; M40; OK/SW-cl.56; Talpha1 alpha-tubulin; Tuba1; Tuba-1; TUBA1A; TUBA3; TUBB; TUBB1; TUBB2A; TUBB5; Tubulin alpha; tubulin alpha 1a; tubulin alpha 3; tubulin alpha-1 chain; Tubulin alpha-1A chain; tubulin alpha-3 chain; Tubulin B-alpha-1; tubulin beta; tubulin beta 1 class VI; tubulin beta chain; tubulin beta class I; tubulin beta-1 chain; Tubulin beta-5 chain; tubulin, alpha 1; tubulin, alpha 1A; tubulin, alpha, brain-specific; tubulin, beta 1 class VI; tubulin, beta 2A class IIa; tubulin, beta class I; tubulin, beta family 1; tubulin, beta polypeptide; a/β-tubulin
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100134983, 100135051, 203068, 22142, 545486, 64158, 679312, 733686, 7846, 81027
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Rat Albumin
Classification: Polyclonal
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P02769, P02770
Gene Symbols: Alb
Immunogen: Native protein.
Quantity: 1 mg
Primary or Secondary: Primary
Target Species: Bovine, Rat
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry
Conjugate: FITC
Gene: Alb
Gene Alias: Alb; ALB protein; Alb1; albumin; Albza; Bos d 6; bovine serum albumin; BSA; Serum albumin
Host Species: Sheep
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 24186, 280717
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form: Liquid
Antigen:
Rat Albumin
Classification:
Polyclonal
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P02769, P02770
Gene Symbols:
Alb
Immunogen:
Native protein.
Quantity:
1 mg
Primary or Secondary:
Primary
Target Species:
Bovine, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry
Conjugate:
FITC
Gene:
Alb
Gene Alias:
Alb; ALB protein; Alb1; albumin; Albza; Bos d 6; bovine serum albumin; BSA; Serum albumin
Host Species:
Sheep
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
24186, 280717
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form:
Liquid
Antigen: Transferrin
Classification: Polyclonal
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P02787
Gene Symbols: Tf
Immunogen: Pure human transferrin prepared from pooled normal human serum
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry
Conjugate: FITC
Gene: Tf
Gene Alias: AI266983; beta-1 metal-binding globulin; Cd176; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; HEL-S-71p; HP; hpx; hypotransferrinemia with hemochromatosis; ICA; Inhibitor of carbonic anhydrase; lactoferrin; liver regeneration-related protein LRRG03; liver transferrin; LOC100146633; PICA; porcine inhibitor of carbonic anhydrase; porcine inhibitor of carbonic anhydrase precursor; PRO1400; PRO1557; PRO2086; Serotransferrin; siderophilin; TF; Tfn; TFQTL1; transferin; Transferrin; transferrin precursor; Trf
Host Species: Sheep
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 7018
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form: Liquid
Antigen:
Transferrin
Classification:
Polyclonal
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P02787
Gene Symbols:
Tf
Immunogen:
Pure human transferrin prepared from pooled normal human serum
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry
Conjugate:
FITC
Gene:
Tf
Gene Alias:
AI266983; beta-1 metal-binding globulin; Cd176; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; HEL-S-71p; HP; hpx; hypotransferrinemia with hemochromatosis; ICA; Inhibitor of carbonic anhydrase; lactoferrin; liver regeneration-related protein LRRG03; liver transferrin; LOC100146633; PICA; porcine inhibitor of carbonic anhydrase; porcine inhibitor of carbonic anhydrase precursor; PRO1400; PRO1557; PRO2086; Serotransferrin; siderophilin; TF; Tfn; TFQTL1; transferin; Transferrin; transferrin precursor; Trf
Host Species:
Sheep
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
7018
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form:
Liquid