PA3105

Phospho-NMDAR2B (Tyr1336) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA3105-Each-of-1 In Stock ₹ 44,533.98

PA3105 - Each of 1

₹ 44,533.98

In Stock

Quantity

1

Base Price: ₹ 44,533.98

GST (18%): ₹ 8,016.116

Total Price: ₹ 52,550.096

Antigen

Phospho-NMDAR2B (Tyr1336)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GRIN2B

Gene Alias

AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3

Host Species

Rabbit

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 0.05% sodium azide

Gene Accession No.

Q00960, Q01097, Q13224

Gene Symbols

GRIN2B

Immunogen

Synthetic phosphopeptide corresponding to residues C G(1328) R F M D G S P Y(p) H(1337) of rat NMDA receptor 2B.

Regulatory Status

RUO

Gene ID (Entrez)

14812, 24410, 2904

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • PA3-105 detects Phospho-N-methyl-D-aspartate (NMDA) receptor type 2B
  • PA3-105 has been used successfully in Western blot, ELISA, immunoprecipitation, immunohistochemistry, and immunocytochemistry procedures
  • In Western blot analysis of rat brain synaptic membranes this antibody detects a ∽180 kDa protein representing NMDA receptor type 2B
  • The PA3-105 immunogen is a synthetic phosphopeptide corresponding to residues (C) G(1328) R F M D G S P Y(p) H(1337) of rat NMDA receptor 2B
  • NMDAR2B is a member of the N-methyl-D-aspartate (NMDA) class of ionotropic glutamate receptors
  • NMDA receptors (NMDAR) have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning
  • NMDAR play a role in neuronal development and has been implicated in several disorders of the central nervous system including Alzheimer’s Disease, epilepsy and ischemic neuronal cell death
  • Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression
  • Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity
  • NMDR2B is a heterotrimer comprised of seven enetically encoded and differentially expressed subunits that include NR1, NR2 and NR3
  • Diseases associated with the dysfunction of NMDAR2B include epileptic encephalopathy, autosomal dominant 6-related mental retardation.

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PA3105

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Antigen:
Phospho-NMDAR2B (Tyr1336)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRIN2B

Gene Alias:
AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q00960, Q01097, Q13224

Gene Symbols:
GRIN2B

Immunogen:
Synthetic phosphopeptide corresponding to residues C G(1328) R F M D G S P Y(p) H(1337) of rat NMDA receptor 2B.

Regulatory Status:
RUO

Gene ID (Entrez):
14812, 24410, 2904

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PA3111

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Antigen:
SSTR4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SSTR4

Gene Alias:
G-protein coupled receptor; Smstr4; somatostatin receptor; somatostatin receptor 4; Somatostatin receptor subtype 4 Rattus norvegicus Sprague-Dawley major hippocampal somatostatin receptor (SSTR4) mRNA; somatostatin receptor type 4; SS4R; SS-4-R; SS4-R; sst4; Sstr4

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
P31391, P49660

Gene Symbols:
SSTR4

Immunogen:
Synthetic peptide corresponding to residues C(366) Q Q E A L Q P E P G R K R I P L T R T T T F(388) of human SSTR4.

Regulatory Status:
RUO

Gene ID (Entrez):
20608, 6754

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PA3115

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Antigen:
DUSP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DUSP2

Gene Alias:
dual specificity phosphatase 2; dual specificity protein phosphatase 2; Dual specificity protein phosphatase PAC-1; dual-specificity phosphatase 2; Dusp2; PAC1; Pac-1; serine/threonine specific protein phosphatase

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q05922, Q05923

Gene Symbols:
DUSP2

Immunogen:
Synthetic peptide, KLH conjugated, corresponding to the residues L(506) S K S S S Q I R M S G L P A D N L A T(525) of human PAC1.

Regulatory Status:
RUO

Gene ID (Entrez):
13537, 1844

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PA3117

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Antigen:
GHRHR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ghrhr

Gene Alias:
GHRFR; GHRH receptor; GHRHR; Ghrh-r; GHRHREC; GHRHRpsv; GRF receptor; GRFR; Growth hormone - releasing receptor; growth hormone releasing hormone receptor; growth hormone-releasing factor receptor; Growth hormone-releasing hormone receptor; IGHD1B; lit; little

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q02643

Gene Symbols:
Ghrhr

Immunogen:
Synthetic peptide, KLH conjugated, corresponding to residues R(403) T R A K W T T P S R S A A K V L T S M(422) of human GHRH-R.

Regulatory Status:
RUO

Gene ID (Entrez):
2692

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid