PA1884

DNMT3B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA1884-Each-of-1 In Stock ₹ 45,731.82

PA1884 - Each of 1

₹ 45,731.82

In Stock

Quantity

1

Base Price: ₹ 45,731.82

GST (18%): ₹ 8,231.728

Total Price: ₹ 53,963.548

Antigen

DNMT3B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Dnmt3b

Gene Alias

DNA (cytosine-5-)-methyltransferase 3 beta; DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase 3 beta; DNA methyltransferase 3B; DNA methyltransferase HsaIIIB; DNA methyltransferase MmuIIIB; DNA MTase HsaIIIB; DNA MTase MmuIIIB; Dnmt3; DNMT3B; ICF; ICF1; M.HsaIIIB; m.MmuIIIB; MGC1090; MmuIIIB

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13436, 1789

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

O88509, Q9UBC3

Gene Symbols

Dnmt3b

Immunogen

Synthetic peptide corresponding to the residues M(1) K G D S R H L N E E E G A(14) C of mouse DNMT3b

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-884 detects DNA methyltransferase 3 from human and mouse tissues and cells as well as recombinant human Dnmt3
  • This antibody has been used to detect both recombinant and endogenous DNMT3b and recombinant DNMT3a
  • PA1-884 has been successfully used in Immunohistochemistry (paraffin) and Western blot procedures
  • By Western blot, this antibody detects DNMT3 from P19 nuclear extracts
  • The PA1-884 immunogen is a synthetic peptide corresponding to residues 1-14 of mouse DNMT3b
  • This sequence is 79% conserved between human and mouse
  • PA1-884 immunizing peptide (Cat
  • # PEP-117) is available for use in neutralization and control experiments
  • CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation
  • Studies in mice have demonstrated that DNA methylation is required for mammalian development
  • This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation
  • The protein localizes primarily to the nucleus and its expression is developmentally regulated
  • Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome
  • Six alternatively spliced transcript variants have been described
  • The full length sequences of variants 4 and 5 have not been determined.

Compare Similar Items

Show Difference

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Thermo Scientific

PA1884

--


Antigen:
DNMT3B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dnmt3b

Gene Alias:
DNA (cytosine-5-)-methyltransferase 3 beta; DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase 3 beta; DNA methyltransferase 3B; DNA methyltransferase HsaIIIB; DNA methyltransferase MmuIIIB; DNA MTase HsaIIIB; DNA MTase MmuIIIB; Dnmt3; DNMT3B; ICF; ICF1; M.HsaIIIB; m.MmuIIIB; MGC1090; MmuIIIB

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13436, 1789

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
O88509, Q9UBC3

Gene Symbols:
Dnmt3b

Immunogen:
Synthetic peptide corresponding to the residues M(1) K G D S R H L N E E E G A(14) C of mouse DNMT3b

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA1887

--


Antigen:
MECP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mecp2

Gene Alias:
1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17257, 29386, 4204

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P51608, Q00566, Q9Z2D6

Gene Symbols:
Mecp2

Immunogen:
Synthetic Peptide: M(1) V A G M L G L R E E K S E D(15) C

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA1888

--


Antigen:
MECP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mecp2

Gene Alias:
1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17257, 29386, 4204

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P51608, Q00566, Q9Z2D6

Gene Symbols:
Mecp2

Immunogen:
Synthetic Peptide: C P(469) N R E E P V D S R T P V T E R V S(486)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PA1889

--


Antigen:
MBD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MBD1

Gene Alias:
CXXC3; CXXC-type zinc finger protein 3; Mbd1; methyl-CpG binding domain protein 1; methyl-CpG binding domain protein 1 isoform PCM1; methyl-CpG-binding domain protein 1; Methyl-CpG-binding protein MBD1; PCM1; Protein containing methyl-CpG-binding domain 1; RFT; the regulator of fibroblast growth factor 2 (FGF-2) transcription

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4152

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q9UIS9

Gene Symbols:
MBD1

Immunogen:
Synthetic Peptide: C R(593) S K D L K K P G A R K Q(605)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG