PA1960
PSME1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1960-Each-of-1 | In Stock | ₹ 48,213.06 |
PA1960 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,213.06
GST (18%): ₹ 8,678.351
Total Price: ₹ 56,891.411
Antigen
PSME1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PSME1
Gene Alias
11S regulator complex subunit alpha; 29-kD MCP activator subunit; activator of multicatalytic protease subunit 1; AW413925; epididymis secretory sperm binding protein Li 129m; HEL-S-129m; I79_008549; IFI5111; IGUP I-5111; interferon gamma up-regulated I-5111 protein; interferon-gamma IEF SSP 5111; interferon-gamma-inducible protein 5111; MGC8628; OTTHUMP00000164702; PA28 alpha subunit; PA28a; PA28alpha; protease (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) activator subunit 1; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha); proteasome activator 28 subunit alpha; Proteasome activator complex subunit 1; proteasome activator subunit 1; Psme1; REGalpha; REG-alpha
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100761736, 19186, 29630, 480256, 5720
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P97371, Q06323, Q63797
Gene Symbols
PSME1
Immunogen
Synthetic Peptide: R(5) V Q P E A Q A K V D V F R E D L C(22)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Canine, Hamster, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-960 detects proteasome activator 11S REG alpha subunit from canine, hamster, human, mouse and rat tissues and cells
- PA1-960 has been successfully used in Western blot procedures
- By Western blot, this antibody detects a 28 kDa protein representing 11S REG alpha subunit in rat brain extract
- PA1-960 immunizing peptide corresponds to amino acid residues 5-22 of human proteasome activator 11S REG alpha
- This sequence differs from the mouse and rat 11S REG alpha protein by a single amino acid residue
- PA1-960 immunizing peptide (Cat
- # PEP-097) is available for use in neutralization and control experiments
- Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors
- The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus
- Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum
- The 26S proteasome is an ATP-dependent, multisubunit (approximately 31), barrel-shaped molecular machine with an apparent molecular weight of approximately 2.5 MDa
- It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes
- The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit
- An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation
- Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway
- Some examples of affected proteins include those linked to cystic fibrosis, Angelman's syndrome, and Liddle syndrome.
Compare Similar Items
Show Difference
Antigen: PSME1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PSME1
Gene Alias: 11S regulator complex subunit alpha; 29-kD MCP activator subunit; activator of multicatalytic protease subunit 1; AW413925; epididymis secretory sperm binding protein Li 129m; HEL-S-129m; I79_008549; IFI5111; IGUP I-5111; interferon gamma up-regulated I-5111 protein; interferon-gamma IEF SSP 5111; interferon-gamma-inducible protein 5111; MGC8628; OTTHUMP00000164702; PA28 alpha subunit; PA28a; PA28alpha; protease (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) activator subunit 1; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha); proteasome activator 28 subunit alpha; Proteasome activator complex subunit 1; proteasome activator subunit 1; Psme1; REGalpha; REG-alpha
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100761736, 19186, 29630, 480256, 5720
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P97371, Q06323, Q63797
Gene Symbols: PSME1
Immunogen: Synthetic Peptide: R(5) V Q P E A Q A K V D V F R E D L C(22)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Hamster, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PSME1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PSME1
Gene Alias:
11S regulator complex subunit alpha; 29-kD MCP activator subunit; activator of multicatalytic protease subunit 1; AW413925; epididymis secretory sperm binding protein Li 129m; HEL-S-129m; I79_008549; IFI5111; IGUP I-5111; interferon gamma up-regulated I-5111 protein; interferon-gamma IEF SSP 5111; interferon-gamma-inducible protein 5111; MGC8628; OTTHUMP00000164702; PA28 alpha subunit; PA28a; PA28alpha; protease (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) activator subunit 1; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha); proteasome activator 28 subunit alpha; Proteasome activator complex subunit 1; proteasome activator subunit 1; Psme1; REGalpha; REG-alpha
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100761736, 19186, 29630, 480256, 5720
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P97371, Q06323, Q63797
Gene Symbols:
PSME1
Immunogen:
Synthetic Peptide: R(5) V Q P E A Q A K V D V F R E D L C(22)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Hamster, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PSMD2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PSMD2
Gene Alias: 26S proteasome non-ATPase regulatory subunit 2; 26S proteasome non-ATPase regulatory subunit 2-like protein; 26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; 55.11 protein; 9430095H01Rik; AA407121; F23F1.8; I79_017809; MGC14274; P97; proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; proteasome 26S subunit, non-ATPase 2; protein 55.11; PSMD2; RPN1; S2; TEG-190; testis expressed gene 190; Tex190; TNFR-associated protein 2; TRAP2; Tumor necrosis factor type 1 receptor-associated protein 2
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 5708
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: Q13200
Gene Symbols: PSMD2
Immunogen: Human recombinant proteasome 19S subunit S2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PSMD2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PSMD2
Gene Alias:
26S proteasome non-ATPase regulatory subunit 2; 26S proteasome non-ATPase regulatory subunit 2-like protein; 26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; 55.11 protein; 9430095H01Rik; AA407121; F23F1.8; I79_017809; MGC14274; P97; proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; proteasome 26S subunit, non-ATPase 2; protein 55.11; PSMD2; RPN1; S2; TEG-190; testis expressed gene 190; Tex190; TNFR-associated protein 2; TRAP2; Tumor necrosis factor type 1 receptor-associated protein 2
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5708
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
Q13200
Gene Symbols:
PSMD2
Immunogen:
Human recombinant proteasome 19S subunit S2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PSMC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Psmc1
Gene Alias: 26S protease regulatory subunit 4; 26S proteasome AAA-ATPase subunit RPT2; 26S proteasome regulatory subunit 4; AI325227; MGC24583; MGC8541; P26s4; p56; peptidase (prosome, macropain) 26S subunit, ATPase 1; protease (prosome, macropain) 26S subunit, ATPase 1; proteasome (prosome, macropain) 26S subunit, ATPase, 1; proteasome 26S ATPase subunit 1; proteasome 26S subunit ATPase 1; proteasome 26S subunit, ATPase 1; proteasome 26S subunit, ATPase, 1; prs4; Psmc1; rpt2; Rpt2/S4; S4
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 5700
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: Conc. Not Determined
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P62191
Gene Symbols: Psmc1
Immunogen: Yeast proteasome 19S subunit S4.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PSMC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Psmc1
Gene Alias:
26S protease regulatory subunit 4; 26S proteasome AAA-ATPase subunit RPT2; 26S proteasome regulatory subunit 4; AI325227; MGC24583; MGC8541; P26s4; p56; peptidase (prosome, macropain) 26S subunit, ATPase 1; protease (prosome, macropain) 26S subunit, ATPase 1; proteasome (prosome, macropain) 26S subunit, ATPase, 1; proteasome 26S ATPase subunit 1; proteasome 26S subunit ATPase 1; proteasome 26S subunit, ATPase 1; proteasome 26S subunit, ATPase, 1; prs4; Psmc1; rpt2; Rpt2/S4; S4
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
5700
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
Conc. Not Determined
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P62191
Gene Symbols:
Psmc1
Immunogen:
Yeast proteasome 19S subunit S4.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PSMC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PSMC2
Gene Alias: 26S protease regulatory subunit 7; 26S proteasome AAA-ATPase subunit RPT1; 26S proteasome regulatory subunit 7; mammalian suppressor of sgv-1 of yeast; MGC3004; MSS1; Nbla10058; protease 26S subunit 7; proteasome (prosome, macropain) 26S subunit, ATPase 2; proteasome (prosome, macropain) 26S subunit, ATPase, 2; proteasome 26S subunit ATPase 2; proteasome 26S subunit, ATPase 2; proteasome 26S subunit, ATPase, 2; Protein MSS1; PSMC2; putative protein product of Nbla10058; S7; testis secretory sperm-binding protein Li 197a
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 5701
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: Conc. Not Determined
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P35998
Gene Symbols: PSMC2
Immunogen: Human recombinant proteasome 19S subunit S7.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PSMC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PSMC2
Gene Alias:
26S protease regulatory subunit 7; 26S proteasome AAA-ATPase subunit RPT1; 26S proteasome regulatory subunit 7; mammalian suppressor of sgv-1 of yeast; MGC3004; MSS1; Nbla10058; protease 26S subunit 7; proteasome (prosome, macropain) 26S subunit, ATPase 2; proteasome (prosome, macropain) 26S subunit, ATPase, 2; proteasome 26S subunit ATPase 2; proteasome 26S subunit, ATPase 2; proteasome 26S subunit, ATPase, 2; Protein MSS1; PSMC2; putative protein product of Nbla10058; S7; testis secretory sperm-binding protein Li 197a
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
5701
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
Conc. Not Determined
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P35998
Gene Symbols:
PSMC2
Immunogen:
Human recombinant proteasome 19S subunit S7.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG