PA1969

PSMC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA1969-Each-of-1 In Stock ₹ 49,624.80

PA1969 - Each of 1

₹ 49,624.80

In Stock

Quantity

1

Base Price: ₹ 49,624.80

GST (18%): ₹ 8,932.464

Total Price: ₹ 58,557.264

Antigen

PSMC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PSMC2

Gene Alias

26S protease regulatory subunit 7; 26S proteasome AAA-ATPase subunit RPT1; 26S proteasome regulatory subunit 7; mammalian suppressor of sgv-1 of yeast; MGC3004; MSS1; Nbla10058; protease 26S subunit 7; proteasome (prosome, macropain) 26S subunit, ATPase 2; proteasome (prosome, macropain) 26S subunit, ATPase, 2; proteasome 26S subunit ATPase 2; proteasome 26S subunit, ATPase 2; proteasome 26S subunit, ATPase, 2; Protein MSS1; PSMC2; putative protein product of Nbla10058; S7; testis secretory sperm-binding protein Li 197a

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

5701

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

Conc. Not Determined

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P35998

Gene Symbols

PSMC2

Immunogen

Human recombinant proteasome 19S subunit S7.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-969 detects proteasome 19S subunit S7 from human cells
  • PA1-969 has been successfully used in Western blot and immunoprecipitation procedures
  • By Western blot, this antibody detects a 47 kDa protein representing proteasome 19S subunit S7 from HeLa cell lysate
  • PA1-969 antigen is recombinant human proteasome 19S subunit S7
  • Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors
  • The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus
  • Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum
  • The 26S proteasome is an ATP-dependent, multisubunit (∽31), barrel-shaped molecular machine with an apparent molecular weight of ∽2.5 MDa
  • It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes
  • The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit
  • An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation
  • Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway
  • Some examples of affected proteins include those linked to cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.

Compare Similar Items

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Thermo Scientific

PA1969

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Antigen:
PSMC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSMC2

Gene Alias:
26S protease regulatory subunit 7; 26S proteasome AAA-ATPase subunit RPT1; 26S proteasome regulatory subunit 7; mammalian suppressor of sgv-1 of yeast; MGC3004; MSS1; Nbla10058; protease 26S subunit 7; proteasome (prosome, macropain) 26S subunit, ATPase 2; proteasome (prosome, macropain) 26S subunit, ATPase, 2; proteasome 26S subunit ATPase 2; proteasome 26S subunit, ATPase 2; proteasome 26S subunit, ATPase, 2; Protein MSS1; PSMC2; putative protein product of Nbla10058; S7; testis secretory sperm-binding protein Li 197a

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
5701

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P35998

Gene Symbols:
PSMC2

Immunogen:
Human recombinant proteasome 19S subunit S7.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA1972

--


Antigen:
PSMB8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Psmb8

Gene Alias:
ALDD; D6S216; D6S216E; DAAP-57C1.3; JMP; large multifunctional protease 7; Lmp7; Lmp-7; low molecular mass polypeptide 7; low molecular mass protein 7; low molecular weight protein 7; macropain subunit C13; Mc13; MC13 (LMP7); MGC1491; multicatalytic endopeptidase complex subunit C13; NKJO; OTTHUMP00000029420; OTTHUMP00000029421; OTTHUMP00000062981; protease component C13; proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); proteasome (prosome, macropain) subunit, beta type, 8; proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7); proteasome catalytic subunit 3i; proteasome component C13; proteasome subunit beta 5i; proteasome subunit beta 8; proteasome subunit beta type 8; proteasome subunit beta type-8; Proteasome subunit beta-5i; proteasome subunit MC13; proteasome subunit Y2; proteasome-related gene 7; proteosome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); proteosome beta 8 subunit; PSMB5i; Psmb8; Really interesting new gene 10 protein; Ring10; Y2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5696

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P28062

Gene Symbols:
Psmb8

Immunogen:
Synthetic Peptide: C V(259) E S T D V S D L L H Q Y R E A(274)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA1978

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Antigen:
PSMB6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSMB6

Gene Alias:
DELTA; Lmp19; LMPY; low molecular mass protein 19; Macropain delta chain; Mpnd; multicatalytic endopeptidase complex delta chain; proteasome (prosome, macropain) subunit, beta type 6; proteasome (prosome, macropain) subunit, beta type, 6; proteasome 20S subunit beta 6; proteasome beta 6 subunit; proteasome catalytic subunit 1; proteasome chain 5; Proteasome delta chain; proteasome subunit beta 6; proteasome subunit beta type-6; proteasome subunit delta; proteasome subunit Y; Psmb6; Psmb6l; PSY large multifunctional protease Y; RP23-122P1.4; subunit 2; Y

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19175, 29666, 510069, 5694

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P28072, P28073, Q3MHN0, Q60692

Gene Symbols:
PSMB6

Immunogen:
Synthetic Peptides: C(41) R S G S A A D T Q A V/I A D A V T Y(58)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA1980A

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Antigen:
GFP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
GFP; GFP tag; GFP2; green fluorescence; green fluorescent; Turbo eGFP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Synthetic Peptide: H(26) K F S V S G E G E G D A T(39) C

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Tag

Product Type:
Antibody

Isotype:
IgG