PA3843
E6AP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA3843-Each-of-1 | In Stock | ₹ 46,074.06 |
PA3843 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,074.06
GST (18%): ₹ 8,293.331
Total Price: ₹ 54,367.391
Antigen
E6AP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
UBE3A
Gene Alias
4732496B02; 5830462N02Rik; A130086L21Rik; ANCR; AS; CTCL tumor antigen se37-2; E6AP; E6-AP; E6-AP ubiquitin protein ligase; E6AP ubiquitin-protein ligase; EPVE6AP; FLJ26981; HECT-type ubiquitin transferase E3A; HPVE6A; human papilloma virus E6-associated protein; human papillomavirus E6-associated protein; mKIAA4216; oncogenic protein-associated protein E6-AP; Renal carcinoma antigen NY-REN-54; UBE3A; ubiquitin conjugating enzyme E3A; ubiquitin protein ligase E3A; ubiquitin-protein ligase E3A
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunoprecipitation, Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum diluted in PBS with 0.05% sodium azide
Gene Accession No.
Q05086
Gene Symbols
UBE3A
Immunogen
Full-length human E6-AP:GST fusion protein.
Regulatory Status
RUO
Gene ID (Entrez)
7337
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- PA3-843 detects Angelman Syndrome-Associated protein (E6-AP) from human tissues
- PA3-843 has been successfully used in Western blot and immunoprecipitation procedures
- By Western blot, this antibody detects a single ∽100 kDa protein representing E6-AP from HeLa cell lysate
- IMPORTANT: E6-AP is a very labile protein
- Freeze/thaw cycling of samples results in E6-AP degradation which is observed as a prominent 50 kDa band seen in Western blots
- PA3-843 antigen is bacterially expressed, full-length human E6-AP
- UBE3A (ubiquitin-protein ligase E3A, AKA E6AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates
- Several substrates have been identified including the ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B
- Additionally, UBE3A may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins
- UBE3A also plays an important role in the regulation of the circadian clock
- Defects in UBE3A are a cause of Angelman syndrome (AS).
Compare Similar Items
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Antigen: E6AP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: UBE3A
Gene Alias: 4732496B02; 5830462N02Rik; A130086L21Rik; ANCR; AS; CTCL tumor antigen se37-2; E6AP; E6-AP; E6-AP ubiquitin protein ligase; E6AP ubiquitin-protein ligase; EPVE6AP; FLJ26981; HECT-type ubiquitin transferase E3A; HPVE6A; human papilloma virus E6-associated protein; human papillomavirus E6-associated protein; mKIAA4216; oncogenic protein-associated protein E6-AP; Renal carcinoma antigen NY-REN-54; UBE3A; ubiquitin conjugating enzyme E3A; ubiquitin protein ligase E3A; ubiquitin-protein ligase E3A
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum diluted in PBS with 0.05% sodium azide
Gene Accession No.: Q05086
Gene Symbols: UBE3A
Immunogen: Full-length human E6-AP:GST fusion protein.
Regulatory Status: RUO
Gene ID (Entrez): 7337
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
E6AP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
UBE3A
Gene Alias:
4732496B02; 5830462N02Rik; A130086L21Rik; ANCR; AS; CTCL tumor antigen se37-2; E6AP; E6-AP; E6-AP ubiquitin protein ligase; E6AP ubiquitin-protein ligase; EPVE6AP; FLJ26981; HECT-type ubiquitin transferase E3A; HPVE6A; human papilloma virus E6-associated protein; human papillomavirus E6-associated protein; mKIAA4216; oncogenic protein-associated protein E6-AP; Renal carcinoma antigen NY-REN-54; UBE3A; ubiquitin conjugating enzyme E3A; ubiquitin protein ligase E3A; ubiquitin-protein ligase E3A
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum diluted in PBS with 0.05% sodium azide
Gene Accession No.:
Q05086
Gene Symbols:
UBE3A
Immunogen:
Full-length human E6-AP:GST fusion protein.
Regulatory Status:
RUO
Gene ID (Entrez):
7337
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: IFIT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IFIT1
Gene Alias: C56; G10P1; Garg16; GARG-16; glucocorticoid-attenuated response gene 16 product; glucocorticoid-attenuated response gene 16 protein; Ifi56; IFI-56; IFI-56K; IFIT1; IFIT-1; IFNAI1; interferon induced protein with tetratricopeptide repeats 1; interferon, alpha-inducible protein (MW 56kD); interferon-induced 56 kDa protein; Interferon-induced protein with tetratricopeptide repeats 1; interferon-induced protein with tetratricopeptide repeats 1-like protein; interferon-inducible mRNA 561; Isg56; P56; RNM561
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with 0.05% sodium azide
Gene Accession No.: Q64282
Gene Symbols: IFIT1
Immunogen: aa 217-233 of mouse IFIT1
Regulatory Status: RUO
Gene ID (Entrez): 15957
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
IFIT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IFIT1
Gene Alias:
C56; G10P1; Garg16; GARG-16; glucocorticoid-attenuated response gene 16 product; glucocorticoid-attenuated response gene 16 protein; Ifi56; IFI-56; IFI-56K; IFIT1; IFIT-1; IFNAI1; interferon induced protein with tetratricopeptide repeats 1; interferon, alpha-inducible protein (MW 56kD); interferon-induced 56 kDa protein; Interferon-induced protein with tetratricopeptide repeats 1; interferon-induced protein with tetratricopeptide repeats 1-like protein; interferon-inducible mRNA 561; Isg56; P56; RNM561
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum with 0.05% sodium azide
Gene Accession No.:
Q64282
Gene Symbols:
IFIT1
Immunogen:
aa 217-233 of mouse IFIT1
Regulatory Status:
RUO
Gene ID (Entrez):
15957
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: IGF2R
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IGF2R
Gene Alias: 300 kDa mannose 6-phosphate receptor; AI661837; cation-independent mannose 6-phosphate receptor; cation-independent mannose 6-phosphate receptor protein; cation-independent mannose-6-phosphate receptor; cation-independent MPR; CD222; CI Man-6-P receptor; CI-M6PR; CIMPR; CI-MPR; Igf2r; IGF-II receptor; IGF-II/CI-MPR; Igfr2; insulin like growth factor 2 receptor; insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; insulin-like growth factor receptor type 2; M6P; M6P/IGF2 receptor; M6P/IGF2R; M6PR; M6P-R; mannose-6-phosphate receptor, cation independent; mannose-6-phosphate/insulin-like growth factor II receptor; MPR 300; MPR1; MPR300; MPRI; similar to mannose-6-phosphate/insulin-like growth factor II receptor
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG
Applications: Dot Blot, Immunocytochemistry, Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with 0.05% sodium azide
Gene Accession No.: P08169, P11717, Q07113
Gene Symbols: IGF2R
Immunogen: 300 kDa cation-independent receptor purified from adult bovine liver tissue.
Regulatory Status: RUO
Gene ID (Entrez): 16004, 281849, 3482
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
IGF2R
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IGF2R
Gene Alias:
300 kDa mannose 6-phosphate receptor; AI661837; cation-independent mannose 6-phosphate receptor; cation-independent mannose 6-phosphate receptor protein; cation-independent mannose-6-phosphate receptor; cation-independent MPR; CD222; CI Man-6-P receptor; CI-M6PR; CIMPR; CI-MPR; Igf2r; IGF-II receptor; IGF-II/CI-MPR; Igfr2; insulin like growth factor 2 receptor; insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; insulin-like growth factor receptor type 2; M6P; M6P/IGF2 receptor; M6P/IGF2R; M6PR; M6P-R; mannose-6-phosphate receptor, cation independent; mannose-6-phosphate/insulin-like growth factor II receptor; MPR 300; MPR1; MPR300; MPRI; similar to mannose-6-phosphate/insulin-like growth factor II receptor
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Applications:
Dot Blot, Immunocytochemistry, Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum with 0.05% sodium azide
Gene Accession No.:
P08169, P11717, Q07113
Gene Symbols:
IGF2R
Immunogen:
300 kDa cation-independent receptor purified from adult bovine liver tissue.
Regulatory Status:
RUO
Gene ID (Entrez):
16004, 281849, 3482
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Calreticulin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CALR
Gene Alias: Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Non-human Primate, Rabbit, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with 0.05% sodium azide
Gene Accession No.: P14211, P15253, P18418, P27797, P28490
Gene Symbols: CALR
Immunogen: Recombinant, human calreticulin protein.
Regulatory Status: RUO
Gene ID (Entrez): 100009050, 100350417, 12317, 476694, 64202, 811
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Calreticulin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CALR
Gene Alias:
Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Non-human Primate, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum with 0.05% sodium azide
Gene Accession No.:
P14211, P15253, P18418, P27797, P28490
Gene Symbols:
CALR
Immunogen:
Recombinant, human calreticulin protein.
Regulatory Status:
RUO
Gene ID (Entrez):
100009050, 100350417, 12317, 476694, 64202, 811
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid