PA540222

Phospho-Caspase 9 (Ser196) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA540222-Each-of-1 In Stock ₹ 44,705.10

PA540222 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-Caspase 9 (Ser196)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CASP9

Gene Alias

25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

842

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P55211

Gene Symbols

CASP9

Immunogen

Synthesized peptide derived from human Caspase-9 around the phosphorylation site of S196.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PA540260

--

Img

Thermo Scientific

FERMA548403

--

Img

Thermo Scientific

PA540200

--

Img

Thermo Scientific

PA14650

--

Img

Thermo Scientific

PA540250

--

Img

Thermo Scientific

PA540294

--

Img

Thermo Scientific

PA540244

--

Img

Thermo Scientific

PA540214

--

Description

  • Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain
  • Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
  • Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria
  • Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6
  • Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution
  • Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3
  • Caspase 9 promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, and proteolytically cleaves poly(ADP- ribose) polymerase (PARP)
  • Caspase 9 is expressed in variety of human tissues
  • An isoform of rat Caspase-9 has been identified in which the C terminus of full-length Caspase-9 is replaced with an alternative peptide sequence
  • Mutations in Caspase 9 affect brain development
  • In mice, insufficient Caspase 9 have resulted in abnormal cerebrum development and neuron development
  • In humans, dysfunctional Caspase 9 expression vary from tissue to tissue
  • Low levels of Caspase 9 may play a role in cancer development and neurodegenerative diseases such as Alzheimer’s Disease (AD).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PA540222

--


Antigen:
Phospho-Caspase 9 (Ser196)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CASP9

Gene Alias:
25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
842

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P55211

Gene Symbols:
CASP9

Immunogen:
Synthesized peptide derived from human Caspase-9 around the phosphorylation site of S196.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA540225

--


Antigen:
Phospho-CD40 (Thr254)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21939, 958

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P25942, P27512

Gene Symbols:
CD40

Immunogen:
Synthesized peptide derived from human CD40 around the phosphorylation site of T254.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA540226

--


Antigen:
Phospho-CK2 alpha-1 (Tyr255)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CSNK2A1

Gene Alias:
casein kinase 2 alpha; casein kinase 2 alpha'; casein kinase 2 alpha 1; casein kinase 2 alpha 2; casein kinase 2, alpha 1 polypeptide; casein kinase 2, alpha prime polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; casein kinase II subunit alpha; Casein kinase II subunit alpha'; casein kinase II, alpha 1 polypeptide; casein kinase II, alpha 1 related sequence 4; CK II alpha; CK II alpha'; CK II alpha 3; CK2 catalytic subunit alpha; CK2A1; CK2A2; CK2alpha'; CKII; Ckiia; CSNK2A1; Csnk2a1-rs4; CSNK2A2; CSNK2A3; protein kinase CK2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116549, 12995, 1457

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P19139, P68400, Q60737

Gene Symbols:
CSNK2A1

Immunogen:
Synthesized peptide derived from human Casein Kinase IIalpha around the phosphorylation site of Y255.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA540227

--


Antigen:
Phospho-CK1 alpha (Tyr321)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CSNK1A1

Gene Alias:
2610208K14Rik; 4632404G05Rik; 5430427P18Rik; casein kinase 1 alpha 1; casein kinase 1 alpha 1 like; casein kinase 1 alpha 1 S homeolog; casein kinase 1 alpha 1 S homeolog; casein kinase 1, alpha 1; casein kinase 1 alpha isoform; casein kinase 1, alpha 1; casein kinase 1alpha S; casein kinase 1-alphaL; casein kinase 1-alphaLS; casein kinase I; casein kinase I alpha; casein kinase I alpha L isoform; casein kinase I alpha LS; casein kinase I alpha S; Casein kinase I isoform alpha; casein kinase I isoform alpha; casein kinase I; casein kinase I-alpha; CHUNP6894; CK I alpha; CK1; ck1 alpha; CK1a; ck1alpha; CK1alphaS; CKI alpha; CK-I alpha; CKIa; CKI-alpha; clock regulator kinase; Csnk1a; csnk1a1; CSNK1A1 protein; csnk1a1.S; CSNK1A1/CK1; CSNK1A1L; down-regulated in lung cancer; epididymis secretory sperm binding protein Li 77p; HEL-S-77p; HLCDGP1; OTTHUMP00000224000; OTTHUMP00000224001; OTTHUMP00000224003; PRO2975; protein kinase; sb:eu866; wu:fb65a02; wu:fi30h04; wu:fj19c11; XELAEV_18021437mg; YIL035C; zgc:92158

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
113927, 1452, 93687

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P48729, P97633, Q8BK63

Gene Symbols:
CSNK1A1

Immunogen:
Synthesized peptide derived from human Casein Kinase Ialpha around the phosphorylation site of Y321.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG