PA540304

Phospho-beta Catenin (Ser552) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA540304-Each-of-1 In Stock ₹ 44,876.22

PA540304 - Each of 1

₹ 44,876.22

In Stock

Quantity

1

Base Price: ₹ 44,876.22

GST (18%): ₹ 8,077.72

Total Price: ₹ 52,953.94

Antigen

Phospho-beta Catenin (Ser552)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CTNNB1

Gene Alias

armadillo; armadillo homolog; Bcatenin; b-catenin; beta 1 88kDa; beta catenin; Betacatenin; beta-catenin; beta-catenin 1; Bfc; C20orf33; Cadherin associated protein; catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein) beta 1; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; catenin beta 1; catenin beta 1 L homeolog; Catenin beta1; Catenin beta-1; Catenin β 1; Catenin β1; Catnb; CHBCAT; CTNB1; CTNNB; ctnnb1; ctnnb1.L; ctnnb1-a; ctnnb1-b; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; id:ibd2058; Mesc; MRD19; NAP; NYD-SP19; OK/SW-cl.35; OTTHUMP00000209289; P14L; PP8304; PRO2286; RP5-1118M15.1; wu:fb73e10; wu:fi81c06; wu:fk25h01; XELAEV_18031149mg; β catenin; βcatenin

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12387, 1499, 84353

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P35222, Q02248, Q9WU82

Gene Symbols

CTNNB1

Immunogen

Synthesized peptide derived from human Catenin-beta around the phosphorylation site of S552.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with human and rat based on sequence homology
  • Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures
  • AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells
  • Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton
  • Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless
  • The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis
  • Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats
  • A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development
  • In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation
  • The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.

Compare Similar Items

Show Difference

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PA540304

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Antigen:
Phospho-beta Catenin (Ser552)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTNNB1

Gene Alias:
armadillo; armadillo homolog; Bcatenin; b-catenin; beta 1 88kDa; beta catenin; Betacatenin; beta-catenin; beta-catenin 1; Bfc; C20orf33; Cadherin associated protein; catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein) beta 1; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; catenin beta 1; catenin beta 1 L homeolog; Catenin beta1; Catenin beta-1; Catenin β 1; Catenin β1; Catnb; CHBCAT; CTNB1; CTNNB; ctnnb1; ctnnb1.L; ctnnb1-a; ctnnb1-b; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; id:ibd2058; Mesc; MRD19; NAP; NYD-SP19; OK/SW-cl.35; OTTHUMP00000209289; P14L; PP8304; PRO2286; RP5-1118M15.1; wu:fb73e10; wu:fi81c06; wu:fk25h01; XELAEV_18031149mg; β catenin; βcatenin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12387, 1499, 84353

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P35222, Q02248, Q9WU82

Gene Symbols:
CTNNB1

Immunogen:
Synthesized peptide derived from human Catenin-beta around the phosphorylation site of S552.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA548115

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Antigen:
ZNF492

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF492

Gene Alias:
KIAA1473; Zinc finger protein 115; zinc finger protein 115 (Y20); zinc finger protein 492; ZNF115; ZNF492

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
57615

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9P255

Gene Symbols:
ZNF492

Immunogen:
KLH conjugated synthetic peptide between 480-509 amino acids from the C-terminal region of human ZNF492.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA548117

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Antigen:
WDR21B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCAF4L1

Gene Alias:
DCAF4L1; DDB1 and CUL4 associated factor 4 like 1; DDB1 and CUL4 associated factor 4-like 1; DDB1- and CUL4-associated factor 4-like protein 1; WD repeat domain 21B; WD repeat-containing protein 21B; WDR21B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
285429

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.45 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q3SXM0

Gene Symbols:
DCAF4L1

Immunogen:
KLH conjugated synthetic peptide between 241-270 amino acids from the C-terminal region of human WDR21B.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA548132

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Antigen:
PLA2G2D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pla2g2d

Gene Alias:
GIID sPLA2; Group IID secretory phospholipase A2; mGIID; phosphatidylcholine 2-acylhydrolase 2D; phospholipase A2 group IID; phospholipase A2, group IID; Pla2a2; PLA2G2D; PLA2IID; secretory phospholipase A2s; secretory-type PLA, stroma-associated homolog; sPLA2-IID; sPLA2S; SPLASH

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
26279

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9UNK4

Gene Symbols:
Pla2g2d

Immunogen:
KLH conjugated synthetic peptide between 105-131 amino acids from the C-terminal region of human PLA2G2D.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG