PA548695

MAP4K3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA548695-Each-of-1 In Stock ₹ 44,277.30

PA548695 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

MAP4K3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP4K3

Gene Alias

4833416M01Rik; 4833416M07Rik; 9530052P13Rik; germinal center kinase-like kinase; germinal center kinase-related protein kinase; GLK; MAP4K3; MAPK/ERK kinase kinase kinase 3; MAPKKKK3; MEK kinase kinase 3; MEKKK 3; MEKKK3; mitogen activated protein kinase kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase kinase 3; RAB8IPL1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

225028, 8491

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q8IVH8, Q99JP0

Gene Symbols

MAP4K3

Immunogen

KLH conjugated synthetic peptide between 501-529 amino acids from the Central region of mouse Map4k3.

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Predicted to react with rat based on sequence homology
  • MAP4K3 (also known as GLK) is a member of the STE20 family of serine/threonine protein kinases and contains N-terminal catalytic domain and C-terminal regulatory domain
  • MAP4K3 is upstream of the MEKK1 target and is stimulated by UV radiation and TNF-alpha and can lead to the activation of the JNK signaling pathway
  • MAP4K3 can directly activate PKC-T, during TCR signaling and people with systemic lupus erythematosus show considerable enhanced MAP4K3 expression and activation of PKC-T, and the kinase IKK in T cells
  • MAP4K3 can act as a pro-apoptotic kinase which orchestrates activation of BAX via the concerted posttranscriptional modulation of PUMA, BAD, and BIM
  • The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha
  • The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway
  • Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase 1 (MEKK1)
  • MAP4K3 previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase 3 (MAP4K3).

Compare Similar Items

Show Difference

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Thermo Scientific

PA548695

--


Antigen:
MAP4K3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP4K3

Gene Alias:
4833416M01Rik; 4833416M07Rik; 9530052P13Rik; germinal center kinase-like kinase; germinal center kinase-related protein kinase; GLK; MAP4K3; MAPK/ERK kinase kinase kinase 3; MAPKKKK3; MEK kinase kinase 3; MEKKK 3; MEKKK3; mitogen activated protein kinase kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase kinase 3; RAB8IPL1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
225028, 8491

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8IVH8, Q99JP0

Gene Symbols:
MAP4K3

Immunogen:
KLH conjugated synthetic peptide between 501-529 amino acids from the Central region of mouse Map4k3.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA548701

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Antigen:
ADCK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADCK2

Gene Alias:
AA408112; AARF; aarF domain containing kinase 2; Adck2; BB006057; MGC20727; putative ubiquinone biosynthesis protein AarF; uncharacterized aarF domain-containing protein kinase 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
57869

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q6NSR3

Gene Symbols:
ADCK2

Immunogen:
KLH conjugated synthetic peptide between 232-259 amino acids from the Central region of mouse Adck2.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PA548731

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Antigen:
OR5H2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OR5H2

Gene Alias:
Olfactory receptor 5H2; olfactory receptor family 5 subfamily H member 2; olfactory receptor OR3-10; olfactory receptor, family 5, subfamily H, member 2; OR3-10; OR5H2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
79310

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8NGV7

Gene Symbols:
OR5H2

Immunogen:
KLH conjugated synthetic peptide between 283-312 amino acids from the C-terminal region of human OR5H2.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA548740

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Antigen:
CRYGB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRYGB

Gene Alias:
Cryg2; Cryg-3; CRY-gamma-B; Crygb; crystallin gamma B; crystallin, gamma 1-2; crystallin, gamma B; crystallin, gamma polypeptide 2; CTRCT39; DGcry-3; Gamma-B-crystallin; gammaB-crystallin; gamma-crystallin 1-2; Gamma-crystallin 3; gamma-crystallin B; Len; Nop; nuclear opacity

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1419

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P07316

Gene Symbols:
CRYGB

Immunogen:
KLH conjugated synthetic peptide between 68-97 amino acids from the Central region of human CRYGB.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG