PA550385

CPSF4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550385-Each-of-1 In Stock ₹ 45,218.46

PA550385 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

CPSF4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CPSF4

Gene Alias

30kDa; C79664; cleavage and polyadenylation specific factor 4; cleavage and polyadenylation specific factor 4, 30kD subunit; cleavage and polyadenylation specific factor 4, 30kDa; cleavage and polyadenylation specificity factor 30 kDa subunit; Cleavage and polyadenylation specificity factor subunit 4; clipper homolog; Clipper/CPSF 30K; CPSF 30 kDa subunit; Cpsf30; CPSF4; musculus clipper/cleavage and polyadenylation specificity factor 30 kDa subunit; NAR; NEB1; NEB-1; no; no arches homolog; no arches-like zinc finger protein; NS1 effector domain-binding protein 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10898

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1.5 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

O95639

Gene Symbols

CPSF4

Immunogen

Full length fusion protein of Human CPSF4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total CPSF4 protein
  • Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain
  • The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs
  • In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit
  • Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs
  • Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs
  • Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Compare Similar Items

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Img

Thermo Scientific

PA550385

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Antigen:
CPSF4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CPSF4

Gene Alias:
30kDa; C79664; cleavage and polyadenylation specific factor 4; cleavage and polyadenylation specific factor 4, 30kD subunit; cleavage and polyadenylation specific factor 4, 30kDa; cleavage and polyadenylation specificity factor 30 kDa subunit; Cleavage and polyadenylation specificity factor subunit 4; clipper homolog; Clipper/CPSF 30K; CPSF 30 kDa subunit; Cpsf30; CPSF4; musculus clipper/cleavage and polyadenylation specificity factor 30 kDa subunit; NAR; NEB1; NEB-1; no; no arches homolog; no arches-like zinc finger protein; NS1 effector domain-binding protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10898

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1.5 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O95639

Gene Symbols:
CPSF4

Immunogen:
Full length fusion protein of Human CPSF4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550386

--


Antigen:
CRELD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRELD2

Gene Alias:
5730592L21Rik; C85758; CREL2; CRELD2; cysteine rich with EGF like domains 2; cysteine rich with EGF-like domains 2; cysteine-rich with EGF-like domain protein 2; cysteine-rich with EGF-like domains 2; DKFZp667O055; MGC11256; Protein disulfide isomerase CRELD2; RGD1310614; UNQ185/PRO211

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79174

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q6UXH1

Gene Symbols:
CRELD2

Immunogen:
Fusion protein corresponding to residues near the C terminal of human cysteine-rich with EGF-like domains 2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550387

--


Antigen:
ICAT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTNNBIP1

Gene Alias:
1110008O09Rik; 2310001I19Rik; AW457332; beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; catenin; catenin beta interacting protein 1; catenin, beta interacting protein 1; catenin, beta-interacting protein 1; Catnbip1; Ctnnbip1; ICAT; inhibitor of beta-catenin and Tcf-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56998

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
2.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9NSA3

Gene Symbols:
CTNNBIP1

Immunogen:
Full length fusion protein of Human CTNNBIP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550388

--


Antigen:
CYFIP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYFIP2

Gene Alias:
1500004I01Rik; 6430511D02Rik; AA930218; AU022376; cyfip2; cytoplasmic FMR1 interacting protein 2; cytoplasmic FMR1-interacting protein 2; Kiaa1168; mKIAA1168; p53-inducible protein 121; PIR121

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26999, 76884

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q5SQX6, Q96F07

Gene Symbols:
CYFIP2

Immunogen:
Fusion protein corresponding to residues near the C terminal of human cytoplasmic FMR1 interacting protein 2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG