PA550671
HCAR2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550671-Each-of-1 | In Stock | ₹ 45,646.26 |
PA550671 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
HCAR2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HCAR2
Gene Alias
G protein-coupled receptor 109A; G protein-coupled receptor 109B; G protein-coupled receptor HM74a; Gpr109; Gpr109a; Gpr109b; G-protein coupled receptor 109; G-protein coupled receptor 109A; G-protein coupled receptor HM74; G-protein coupled receptor HM74A; HCA2; Hcar2; HM74; HM74a; HM74b; hydroxycarboxylic acid receptor 2; hydroxy-carboxylic acid receptor 2; interferon-gamma inducible gene, Puma-g; mHM74b; Niacin receptor 1; Niacr1; Nicotinic acid receptor; Protein PUMA-G; PUMAG; PUMA-G; PUMA-G. GPR109; putative seven transmembrane spanning receptor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
338442, 369160, 80885
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
0.6 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q80Z39, Q8TDS4, Q9EP66
Gene Symbols
HCAR2
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human hydroxycarboxylic acid receptor 2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total PUMA gamma protein
- GPR109A (also known as HCA2, HM74a, and NIACR1) is a 42kDa G-protein coupled receptor that belongs to a family of three hydroxyl-carboxylic acid receptors, which also include GPR109B and GPR81
- GPR109A has two known ligands: niacin and butyrate (or its derivative 3-hydroxybutyrate)
- The endogenous ligands for GPR109B and GPR81 are 3-hydroxyl-octanoic acid and 2-hydroxy-propanoate (lactate), respectively
- GPR109A is expressed on adipocytes, neutrophils, Langerhans cells, keratinocytes, intestinal epithelial cells, and intestinal colonic macrophages
- Niacin, also known as nicotinic acid or vitamin B3, is known to improve cholesterol metabolism (LDL/HDL ratio) and reduce inflammation
- It has been demonstrated that this effect is mediated through GPR109A
- Notably, GPR109A also has an essential role in suppressing inflammation and cancer in the colon
- Both GPR109A ligands are produced by colonic commensal bacteria
- In mice, GPR109A expression on intestinal epithelial cells and DCs/macrophages contributes to the suppression of colitis and colon cancer
- In humans, GPR109A is silenced in colon carcinoma cells by DNA methylation, which increases inflammation in the intestinal tract.
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Antigen: HCAR2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HCAR2
Gene Alias: G protein-coupled receptor 109A; G protein-coupled receptor 109B; G protein-coupled receptor HM74a; Gpr109; Gpr109a; Gpr109b; G-protein coupled receptor 109; G-protein coupled receptor 109A; G-protein coupled receptor HM74; G-protein coupled receptor HM74A; HCA2; Hcar2; HM74; HM74a; HM74b; hydroxycarboxylic acid receptor 2; hydroxy-carboxylic acid receptor 2; interferon-gamma inducible gene, Puma-g; mHM74b; Niacin receptor 1; Niacr1; Nicotinic acid receptor; Protein PUMA-G; PUMAG; PUMA-G; PUMA-G. GPR109; putative seven transmembrane spanning receptor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 338442, 369160, 80885
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 0.6 mg/mL
Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q80Z39, Q8TDS4, Q9EP66
Gene Symbols: HCAR2
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human hydroxycarboxylic acid receptor 2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HCAR2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HCAR2
Gene Alias:
G protein-coupled receptor 109A; G protein-coupled receptor 109B; G protein-coupled receptor HM74a; Gpr109; Gpr109a; Gpr109b; G-protein coupled receptor 109; G-protein coupled receptor 109A; G-protein coupled receptor HM74; G-protein coupled receptor HM74A; HCA2; Hcar2; HM74; HM74a; HM74b; hydroxycarboxylic acid receptor 2; hydroxy-carboxylic acid receptor 2; interferon-gamma inducible gene, Puma-g; mHM74b; Niacin receptor 1; Niacr1; Nicotinic acid receptor; Protein PUMA-G; PUMAG; PUMA-G; PUMA-G. GPR109; putative seven transmembrane spanning receptor
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
338442, 369160, 80885
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
0.6 mg/mL
Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q80Z39, Q8TDS4, Q9EP66
Gene Symbols:
HCAR2
Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human hydroxycarboxylic acid receptor 2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TEM5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADGRA2
Gene Alias: 8430414O08Rik; 9530074E10Rik; Adgra2; Adgra3; Adhesion G protein-coupled receptor A2; adhesion G protein-coupled receptor A3; DKFZp434C211; DKFZp434J0911; FLJ14390; G protein-coupled receptor 124; Gpr124; G-protein coupled receptor 124; KIAA1531; LOC100363275; mKIAA1531; Tem5; Tumor endothelial marker 5
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 25960, 78560
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.2 mg/mL
Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q91ZV8, Q96PE1
Gene Symbols: ADGRA2
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human G protein-coupled receptor 124
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TEM5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADGRA2
Gene Alias:
8430414O08Rik; 9530074E10Rik; Adgra2; Adgra3; Adhesion G protein-coupled receptor A2; adhesion G protein-coupled receptor A3; DKFZp434C211; DKFZp434J0911; FLJ14390; G protein-coupled receptor 124; Gpr124; G-protein coupled receptor 124; KIAA1531; LOC100363275; mKIAA1531; Tem5; Tumor endothelial marker 5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
25960, 78560
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q91ZV8, Q96PE1
Gene Symbols:
ADGRA2
Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human G protein-coupled receptor 124
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: GREB1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GREB1
Gene Alias: 5730583K22Rik; 9130004E13; AF180470; AU023194; gene regulated by estrogen in breast cancer; gene regulated by estrogen in breast cancer protein; gene regulated in breast cancer 1 protein; GREB1; growth regulating estrogen receptor binding 1; growth regulating estrogen receptor binding 1; protein GREB1; growth regulation by estrogen in breast cancer 1; id:ibd5087; id:ibd5087 protein; im:7140582; Kiaa0575; mKIAA0575; protein GREB1; protein GREB1-like; RGD1564091; si:ch211-175f11.3; zgc:158681
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9687
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 2.8 mg/mL
Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q4ZG55
Gene Symbols: GREB1
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human growth regulation by estrogen in breast cancer 1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GREB1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GREB1
Gene Alias:
5730583K22Rik; 9130004E13; AF180470; AU023194; gene regulated by estrogen in breast cancer; gene regulated by estrogen in breast cancer protein; gene regulated in breast cancer 1 protein; GREB1; growth regulating estrogen receptor binding 1; growth regulating estrogen receptor binding 1; protein GREB1; growth regulation by estrogen in breast cancer 1; id:ibd5087; id:ibd5087 protein; im:7140582; Kiaa0575; mKIAA0575; protein GREB1; protein GREB1-like; RGD1564091; si:ch211-175f11.3; zgc:158681
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9687
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
2.8 mg/mL
Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q4ZG55
Gene Symbols:
GREB1
Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human growth regulation by estrogen in breast cancer 1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HAS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Has1
Gene Alias: HA synthase 1; HAS; Has1; huHAS1; Hyaluronan synthase 1; hyaluronan synthase1; hyaluronate synthase 1; Hyaluronic acid synthase 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15116, 3036
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.2 mg/mL
Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q61647, Q92839
Gene Symbols: Has1
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human hyaluronan synthase 1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
HAS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Has1
Gene Alias:
HA synthase 1; HAS; Has1; huHAS1; Hyaluronan synthase 1; hyaluronan synthase1; hyaluronate synthase 1; Hyaluronic acid synthase 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15116, 3036
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q61647, Q92839
Gene Symbols:
Has1
Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human hyaluronan synthase 1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG