PA551085

Cdc34 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA551085-Each-of-1 In Stock ₹ 44,705.10

PA551085 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Cdc34

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDC34

Gene Alias

(E3-independent) E2 ubiquitin-conjugating enzyme R1; AI327276; CDC34; cell division cycle 34; cell division cycle 34 homolog; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; serine protease; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme Cdc34; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

216150, 299602, 997

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P49427, Q8CFI2

Gene Symbols

CDC34

Immunogen

Synthesized peptide derived from the Internal region of human Cdc34.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • CDC34 Polyclonal Antibody detects endogenous levels of CDC34 protein
  • Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins
  • In vitro catalyzes 'Lys-48'-linked polyubiquitination
  • Cooperates with the E2 UBCH5C and the SCF (FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation
  • Performs ubiquitin chain elongation building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin
  • UBE2D3 acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin
  • Cooperates with the SCF (SKP2) E3 ligase complex to regulate cell proliferation through ubiquitination and degradation of MYBL2 and KIP1
  • Involved in ubiquitin conjugation and degradation of CREM isoform ICERIIgamma and ATF15 resulting in abrogation of ICERIIgamma- and ATF5-mediated repression of cAMP-induced transcription during both meiotic and mitotic cell cycles
  • Involved in the regulation of the cell cycle G2/M phase through its targeting of the WEE1 kinase for ubiquitination and degradation
  • Also involved in the degradation of beta-catenin
  • Is target of human herpes virus 1 protein ICP0, leading to ICP0-dependent dynamic interaction with proteasomes.

Compare Similar Items

Show Difference

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Thermo Scientific

PA551085

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Antigen:
Cdc34

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC34

Gene Alias:
(E3-independent) E2 ubiquitin-conjugating enzyme R1; AI327276; CDC34; cell division cycle 34; cell division cycle 34 homolog; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; serine protease; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme Cdc34; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
216150, 299602, 997

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P49427, Q8CFI2

Gene Symbols:
CDC34

Immunogen:
Synthesized peptide derived from the Internal region of human Cdc34.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA551086

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Antigen:
Calbindin D28K

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CALB1

Gene Alias:
Brain-2; CAB27; CaBP28K; Calb; CALB1; Calb-1; Calbindin; calbindin 1; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; calbindin D28; calbindin-28K; calbindin-D (28k); CalbindinD28K; CB; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; D-28K; PCD-29; RTVL-H protein; spot 35 protein; Vitamin D-dependent calcium-binding protein, avian-type

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12307, 793, 83839

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P05937, P07171, P12658

Gene Symbols:
CALB1

Immunogen:
Synthesized peptide derived from the C-terminal region of human Calbindin D28K.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA551090

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Antigen:
DPYD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DPYD

Gene Alias:
AI315208; DHP; DHPDHase; dihydropyrimidine dehydrogenase; dihydropyrimidine dehydrogenase [NADP(+)]; Dihydrothymine dehydrogenase; dihydrouracil dehydrogenase; DPD; Dpyd; E330028L06Rik

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1806, 81656, 99586

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O89000, Q12882, Q8CHR6

Gene Symbols:
DPYD

Immunogen:
Synthesized peptide derived from the Internal region of human DPYD.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA551091

--


Antigen:
SPTLC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Sptlc1

Gene Alias:
AW552086; C77762; E030036H05; fc75h04; fp41c08; hLCB1; HSAN; HSAN1; HSN1; hypothetical protein LOC553981; hypothetical protein LOC614165; LBC1; LCB 1; LCB1; long chain base biosynthesis protein 1; MGC14645; rCG_44191; RGD1306617; RP11-118F2.1; serine C-palmitoyltransferase; serine palmitoyltransferase 1; serine palmitoyltransferase long chain base subunit 1; serine palmitoyltransferase subunit 1; serine palmitoyltransferase, long chain base subunit 1; serine-palmitoyl-CoA transferase 1; SPT 1; Spt1; SPTI; sptlc1; wu:fc75h04; wu:fp41c08; zgc:112247

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10558, 268656, 361213

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O15269, O35704

Gene Symbols:
Sptlc1

Immunogen:
Synthesized peptide derived from the C-terminal region of human SPTLC1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG